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Article
First international conference of China on anatomical sciences
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Article
Is a type of low frequency ULF magnetic disturbance a kind of earthquake precursors?
A type of relatively low frequency ULF magnetic disturbance has been generally observed by the magnetic induction-meter since it’s operation at Baijiatuan observatory in Bei**g. As the amplitudes and frequenc...
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Article
Open AccessUnique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing
Leptospirosis is a widely spread disease of global concern. Infection causes flu-like episodes with frequent severe renal and hepatic damage, such as haemorrhage and jaundice. In more severe cases, massive pul...
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Article
Distribution and structural characteristics of the **’an Section of the Weihe Fault
The results of seismic deep reflection, high resolution refraction and shallow artificial seismic exploration indicate that the fault on the northern bank of the Weihe river is composed of two faults, one is t...
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Article
Chosen ciphertext secure fuzzy identity based encryption without ROM
Two new constructions of chosen-ciphertext secure fuzzy identity-based encryption (fuzzy-IBE) schemes without random oracle are proposed. The first scheme combines the modification of chosen-plaintext secure S...
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Article
Synthesis, crystal structures, and catalytic hydrolysis activities of four dinuclear complexes with 1,4,7,10-tetraazacyclododecane and succinate ligands
Four new dinuclear complexes of the type [M2(cyclen)2(suc)]Cl2 · nH2O (M = Co2+, Ni2+, Cu2+, Zn2+, cyclen = 1,4,7,10-tetraazacyclododecane, suc = succinate) have been obtained by the reaction of cyclen and succin...
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Article
Clinical evaluation of oral levofloxacin 500 mg once-daily dosage for treatment of lower respiratory tract infections and urinary tract infections: a prospective multicenter study in China
Levofloxacin (LVFX), a fluoroquinolone agent, has a broad spectrum that covers Gram-positive and -negative bacteria and atypical pathogens. It demonstrates good clinical efficacy in the treatment of various in...
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Article
Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies a susceptibility locus at PLCE1
Li Dong Wang and colleagues report a genome wide association study for esophageal squamous cell carcinoma in the Chinese population. They identify two risk loci at PLCE1 and C20orf54.
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Article
Genome-wide association identifies a susceptibility locus for coronary artery disease in the Chinese Han population
Qing Wang and colleagues report a genome-wide association study for coronary artery disease (CAD) in a Chinese Han population. They identify a locus on chromosome 6p24.1 newly associated with CAD.
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Article
Neutrino Oscillations in the de Sitter and the Anti-de Sitter Space-Time
General expressions of the neutrino oscillation phase in the generally static space-time with spherical symmetry are given. The effect of the gravitational field on the oscillation length is embodied in the gr...
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Article
Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2
Dai Zhang and colleagues report a genome-wide association study for schizophrenia in the Han Chinese population. They identify a new susceptibility locus at 11p11.2 and also identify a locus at 6p21-22.1 in th...
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Article
Effect of Trehalose on PC12 Cells Overexpressing Wild-Type or A53T Mutant α-synuclein
Accumulation of α-synuclein (α-Syn) is a common pathology for both familiar and sporadic Parkinson’s disease (PD), enhancing its clearance might be a promising strategy for treating PD. To assess the potential...
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Article
Population pharmacokinetics of clozapine and its primary metabolite norclozapine in Chinese patients with schizophrenia
To develop a combined population pharmacokinetic model (PPK) to assess the magnitude and variability of exposure to both clozapine and its primary metabolite norclozapine in Chinese patients with refractory sc...
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Article
Bortezomib regulates the chemotactic characteristics of T cells through downregulation of CXCR3/CXCL9 expression and induction of apoptosis
The chemotactic movement of T lymphocytes mediated by chemokines and their receptors plays an important role in the pathogenesis of graft-versus-host disease (GVHD) post-allogeneic hematopoietic stem cell tran...
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Article
Direct and full-scale experimental verifications towards ground–satellite quantum key distribution
Quantum key distribution (QKD) provides the only intrinsically unconditional secure method for communication based on the principle of quantum mechanics. Compared with fibre-based demonstrations, free-space li...
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Article
Re-Examination of the Genotoxic Activity of Water Taken From the Songhua River in P. R. China
The Songhua River, in northeast China, has heavy organic contamination due to domestic sewage and industrial wastewater. Thus, it is important to further determine its genotoxic activity, which is a potential ...
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Chapter and Conference Paper
An Inter-Projection Interpolation (IPI) Approach with Geometric Model Restriction to Reduce Image Dose in Cone Beam CT (CBCT)
Cone beam computed tomography (CBCT) imaging is a key step in image guided radiation therapy (IGRT) to improve tumor targeting. The quality and imaging dose of CBCT are two important factors. However, X-ray sc...
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Article
Open AccessOverexpression of CIP2A is an independent prognostic indicator in nasopharyngeal carcinoma and its depletion suppresses cell proliferation and tumor growth
Cancerous inhibitor of protein phosphatase 2A (CIP2A) is an oncoprotein that acts as a prognostic marker for several human malignancies. In this study, we investigated the clinical significance of CIP2A and it...
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Article
Corrigendum: Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54
Nat. Genet. 42, 759–763 (2010); published online 22 August 2010; corrected after print 27 August 2014 In contrast to the version of this article initially published, the authors now find no evidence to support...
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Article
Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations
Dongxin Lin, Philip Taylor, Li-Dong Wang and colleagues have now pooled three genome-wide association analyses of esophageal squamous cell carcinoma, finding two new risk loci at genome-wide significance and a...
