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1,723 Result(s)
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Article
Restraining growth of Zn dendrites by poly dimethyl diallyl ammonium cations in aqueous electrolytes
Metallic zinc is an excellent anode material for Zn-ion batteries, but the growth of Zn dendrite severely hinders its practical application. Herein, an efficient and economical cationic additive, poly dimethyl...
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Open AccessThe evolving landscape of IL-10, IL-22 and IL-26 in pleurisy especially in tuberculous pleurisy
Pleurisy can be categorized as primary or secondary, arising from immunological, tumorous, or microbial conditions. It often results in lung structure damage and the development of various respiratory issues. ...
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Open AccessThe Role of the Intestinal Flora and Its Derivatives in Neurocognitive Disorders: A Narrative Review from Surgical Perspective
Perioperative neurocognitive dysfunction is a significant concern for population health, impacting postoperative recovery and increasing the financial burden on patients. With an increasing number of surgical ...
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Open AccessCorrection: Unveiling the role of HP1α-HDAC1-STAT1 axis as a therapeutic target for HP1α-positive intrahepatic cholangiocarcinoma
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Open AccessAtmospheric oxidation drove climate change on Noachian Mars
Modern Mars is bipolar, cold, and oxidizing, while early Mars was characterized by icy highlands, episodic warmth and reducing atmosphere. The timing and association of the climate and redox transitions remain...
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Benefits of Hepatitis C Viral Eradication: A Real-World Nationwide Cohort Study in Taiwan
Chronic hepatitis C (CHC) increases the risk of liver cirrhosis (LC) and hepatocellular carcinoma (HCC). This nationwide cohort study assessed the effectiveness of viral eradication of CHC.
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Design parameter optimization method for a prestressed steel structure driven by multi-factor coupling
To achieve efficient structural design, it is crucial to reduce the cost of materials while ensuring structural safety. This study proposes an optimization method for design parameters (DPs) in a prestressed s...
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Open AccessA Phase 3, Randomized, Controlled Trial Evaluating the Efficacy and Safety of Ropeginterferon Alfa-2b in Patients with Moderate COVID-19
Ropeginterferon alfa-2b is a novel mono-pegylated proline-interferon. This clinical study aimed to evaluate its antiviral efficacy of ropeginterferon alfa-2b against SARS-CoV-2 infection.
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Observation on the Analgesic Effect of Different Doses of a Combination of Esketamine and Dexmedetomidine Administered for Percutaneous Endoscopic Transforaminal Discectomy: A Randomized, Double-Blind Controlled Trial
Percutaneous endoscopic transforaminal discectomy (PETD) is an effective method for treating lumbar disc herniation, and is typically performed under local anesthesia. However, inadequate analgesia during the ...
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Article
Molecular docking-aided AIEgen design: concept, synthesis and applications
Aggregate-induced emission luminogens (AIEgens) have been widely used in biological imaging, chemical sensing, and disease treatments. The rational design and construction of AIEgens have received considerable...
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Open AccessNab-paclitaxel plus platinum versus paclitaxel plus platinum as first-line therapy in patients with metastatic or recurrent cervical cancer
This study aimed to assess the efficacy and safety of nanoparticle albumin-bound paclitaxel (nab-paclitaxel) plus platinum versus paclitaxel plus platinum as first-line therapy in patients with metastatic or r...
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TshFNA-Examiner: A Nuclei Segmentation and Cancer Assessment Framework for Thyroid Cytology Image
Examining thyroid fine-needle aspiration (FNA) can grade cancer risks, derive prognostic information, and guide follow-up care or surgery. The digitization of biopsy and deep learning techniques has recently e...
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Open AccessA cocktail nanovaccine targeting key entry glycoproteins elicits high neutralizing antibody levels against EBV infection
Epstein-Barr virus (EBV) infects more than 95% of adults worldwide and is closely associated with various malignancies. Considering the complex life cycle of EBV, develo** vaccines targeting key entry glycop...
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Open AccessSonodynamic and sonomechanical effect on cellular stemness and extracellular physicochemical environment to potentiate chemotherapy
Hypoxia-activated prodrug (HAP) is a promising candidate for highly tumor-specific chemotherapy. However, the oxygenation heterogeneity and dense extracellular matrix (ECM) of tumor, as well as the potential r...
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Open AccessExpression and functional implications of YME1L in nasopharyngeal carcinoma
Mitochondria play a crucial role in the progression of nasopharyngeal carcinoma (NPC). YME1L, a member of the AAA ATPase family, is a key regulator of mitochondrial function and has been implicated in various ...
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Open AccessIdentification and bioinformatics analysis of genes associated with pyroptosis in spinal cord injury of rat and mouse
The mechanism of spinal cord injury (SCI) is highly complex, and an increasing number of studies have indicated the involvement of pyroptosis in the physiological and pathological processes of secondary SCI. H...
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Open AccessLandform and lithospheric development contribute to the assembly of mountain floras in China
Although it is well documented that mountains tend to exhibit high biodiversity, how geological processes affect the assemblage of montane floras is a matter of ongoing research. Here, we explore landform-spec...
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Preparation of nanofibers with Cu/TiO2/rice husk ash photocatalyst and their degradation of methylene blue under visible light
Using the sol–gel method and solid state dispersion, Cu/TiO2 and Cu/TiO2/Rice Husk Ash, are prepared. Moreover, Cu/TiO2/Rice Husk Ash are attached to nylon nanofibers by electrospinning to form nanofibers with Cu...
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Effects of Kv1.3 knockout on pyramidal neuron excitability and synaptic plasticity in piriform cortex of mice
Kv1.3 belongs to the voltage-gated potassium (Kv) channel family, which is widely expressed in the central nervous system and associated with a variety of neuropsychiatric disorders. Kv1.3 is highly expressed ...
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T cell-redirecting antibody for treatment of solid tumors via targeting mesothelin
T cell engaging bispecific antibodies (TCBs) have recently become significant in cancer treatment. In this study we developed MSLN490, a novel TCB designed to target mesothelin (MSLN), a glycosylphosphatidylin...