18 Result(s)

Article

Long-term outcome of children with acute promyelocytic leukemia: a randomized study of oral versus intravenous arsenic by SCCLG-APL group

Realgar-Indigo naturalis formula (RIF), an oral traditional Chinese medicine mainly containing Realgar (As₄S₄), is highly effective in treating adult acute promyelocytic leukemia (APL). However, the treatment eff...

Dan-** Huang, Liang-Chun Yang, Yi-Qiao Chen, Wu-Qing Wan… in Blood Cancer Journal (2023)

Article

Metatranscriptome of human lung microbial communities in a cohort of mechanically ventilated COVID-19 Omicron patients

The Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) infected a substantial proportion of Chinese population, and understanding the factors underlying the severity of the dis...

Lin Wang, Jia-Bao Cao, Bin-Bin **a, Yue-Juan Li… in Signal Transduction and Targeted Therapy (2023)

Article

Transarterial chemoembolization with PD-(L)1 inhibitors plus molecular targeted therapies for hepatocellular carcinoma (CHANCE001)

There is considerable potential for integrating transarterial chemoembolization (TACE), programmed death-(ligand)1 (PD-[L]1) inhibitors, and molecular targeted treatments (MTT) in hepatocellular carcinoma (HCC...

Hai-Dong Zhu, Hai-Liang Li, Ming-Sheng Huang… in Signal Transduction and Targeted Therapy (2023)

Article

Combined angiogenesis and PD-1 inhibition for immunomodulatory TNBC: concept exploration and biomarker analysis in the FUTURE-C-Plus trial

Immune checkpoint inhibitors had a great effect in triple-negative breast cancer (TNBC); however, they benefited only a subset of patients, underscoring the need to co-target alternative pathways and select op...

Song-Yang Wu, Ying Xu, Li Chen, Lei Fan, **ao-Yan Ma, Shen Zhao… in Molecular Cancer (2022)

Article

Evaluation of the Safety and Immune Efficacy of Recombinant Human Respiratory Syncytial Virus Strain Long Live Attenuated Vaccine Candidates

Human respiratory syncytial virus (RSV) infection is the leading cause of lower respiratory tract illness (LRTI), and no vaccine against LRTI has proven to be safe and effective in infants. Our study assessed ...

Li-Nan Wang, **ang-Lei Peng, Min Xu, Yuan-Bo Zheng, Yue-Ying Jiao… in Virologica Sinica (2021)

Article

The effect of the underlying malignancy on short- and medium-term survival of critically ill patients admitted to the intensive care unit: a retrospective analysis based on propensity score matching

Advances in oncology led to a substantial increase in the number of patients requiring admission to the ICU. It is significant to confirm which cancer critical patients can benefit from the ICU care like nonca...

Zhen-nan Yuan, Hai-jun Wang, Yong Gao, Shi-ning Qu, Chu-lin Huang, Hao Wang… in BMC Cancer (2021)

Article

CircLONP2 enhances colorectal carcinoma invasion and metastasis through modulating the maturation and exosomal dissemination of microRNA-17

Metastasis causes the vast majority of colorectal carcinoma (CRC)-related deaths. However, little is known about the specific traits and underlying mechanisms of metastasis-initiating cells in primary CRC. And...

Kai Han, Feng-Wei Wang, Chen-Hui Cao, Han Ling, Jie-Wei Chen… in Molecular Cancer (2020)

Article

A nomogram predicting the recurrence of hepatocellular carcinoma in patients after laparoscopic hepatectomy

Patients with hepatocellular carcinoma (HCC) undergoing surgical resection still have a high 5-year recurrence rate (~ 60%). With the development of laparoscopic hepatectomy (LH), few studies have compared the...

Yang-Xun Pan, Jian-Cong Chen, Ai-** Fang, **ao-Hui Wang… in Cancer Communications (2019)

Article

Role of TGFβ3-Smads-Sp1 axis in DcR3-mediated immune escape of hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a leading cause of tumour-associated mortality worldwide, but no significant improvement in treating HCC has been reported with currently available systemic therapies. Immunot...

Hui-fang Zhu, Yan-** Liu, Ding-li Liu, Yi-dan Ma, Zhi-yan Hu… in Oncogenesis (2019)

Article

Diagnostic value of multislice spiral computed tomography (CT) combined with CT angiography for intra-abdominal undescended testis secondary seminomas

To discuss the diagnostic value of multislice spiral tomography (CT) combined with CT angiography (CTA) technology in intra-abdominal undescended testis secondary seminoma cases.

Si-qi Wang, Fang-yuan Ren, Jian-hua Wang, Zhi-hao Ren, Zhong-gao **… in Cancer Imaging (2019)

Article

Effect of induction chemotherapy with cisplatin, fluorouracil, with or without taxane on locoregionally advanced nasopharyngeal carcinoma: a retrospective, propensity score-matched analysis

Available data in the literature comparing different induction chemotherapy (IC) regimens on locoregionally advanced nasopharyngeal carcinoma (NPC) are scarce. The purpose of the present study was to evaluate ...

Guo-Ying Liu, **ng Lv, Yi-Shan Wu, Min-Jie Mao, Yan-Fang Ye… in Cancer Communications (2018)

Article

Concurrent chemoradiotherapy combined with enteral nutrition support: a radical treatment strategy for esophageal squamous cell carcinoma patients with malignant fistulae

Concurrent chemoradiotherapy (CCRT) significantly increases the survival rate of esophageal squamous cell carcinoma (ESCC) patients with malignant fistulae. Recent clinical evidence has shown the benefits of e...

Li Ma, Guang-Yu Luo, Yu-Feng Ren, Bo Qiu, Hong Yang… in Chinese Journal of Cancer (2017)

Article

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

Andreas Lundqvist, Vincent van Hoef, **aonan Zhang… in Journal for ImmunoTherapy of Cancer (2016)

Article

A new prognostic histopathologic classification of nasopharyngeal carcinoma

The current World Health Organization (WHO) classification of nasopharyngeal carcinoma (NPC) conveys little prognostic information. This study aimed to propose an NPC histopathologic classification that can po...

Hai-Yun Wang, Yih-Leong Chang, Ka-Fai To… in Chinese Journal of Cancer (2016)

Article

Preoperative neutrophil-to-lymphocyte ratio is an independent prognostic marker in patients with laryngeal squamous cell carcinoma

Neutrophil-lymphocyte ratio (NLR) has been shown to be associated with prognosis in various solid tumors. This study aimed to evaluate the prognostic role of NLR in patients with laryngeal squamous cell carcin...

**u-** Tu, Qian-Hui Qiu, Liang-Si Chen, **ao-Ning Luo, Zhong-Ming Lu… in BMC Cancer (2015)

Article

Changes in postmastectomy radiotherapy targets in breast cancer in China between 1999 and 2008: an epidemiological study

To provide evidence that could improve management of breast cancer, we conducted a multi-center retrospective epidemiological study to investigate the status of and changes in postmastectomy radiotherapy (PMRT...

Shu-Lian Wang, Ye-**ong Li, Bao-Ning Zhang, Qing-Kun Song… in Journal of Radiation Oncology (2013)

Article

Breast cancer stage at diagnosis and area-based socioeconomic status: a multicenter 10-year retrospective clinical epidemiological study in China

Although socioeconomic status (SES) has been focused on as a key determinant of cancer stage at diagosis in western countries, there has been no systemic study on the relationship of SES and breast cancer stag...

Qiong Wang, **g Li, Shan Zheng, Jia-Yuan Li, Yi Pang, Rong Huang… in BMC Cancer (2012)

Article

Aurora-A down-regulates IkappaBα via Akt activation and interacts with insulin-like growth factor-1 induced phosphatidylinositol 3-kinase pathway for cancer cell survival

The mitotic Aurora-A kinase exerts crucial functions in maintaining mitotic fidelity. As a bona fide oncoprotein, Aurora-A aberrant overexpression leads to oncogenic transformation. Yet, the mechanisms by whic...

**-e Yao, Min Yan, Zhong Guan, Chao-bin Pan, … in Molecular Cancer (2009)