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Article
Open AccessAsymmetric total synthesis of polycyclic xanthenes and discovery of a WalK activator active against MRSA
The development of new antibiotics continues to pose challenges, particularly considering the growing threat of multidrug-resistant Staphylococcus aureus. Structurally diverse natural products provide a promising...
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Article
Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses
Major depressive disorder, a prevalent and severe psychiatric condition, necessitates development of new and fast-acting antidepressants. Genetic suppression of astrocytic inwardly rectifying potassium channel...
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Article
Open AccessMeasurements of electroweak W±Z boson pair production in association with two jets in pp collisions at \( \sqrt{s} \) = 13 TeV with the ATLAS detector
Measurements of integrated and differential cross-sections for electroweak W±Z production in association with two jets (W±Zjj) in proton-proton collisions are presented. The data collected by the ATLAS detector a...
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Article
Open AccessDeep learning model for the prediction of all-cause mortality among long term care people in China: a prospective cohort study
This study aimed to develop a deep learning model to predict the risk stratification of all-cause death for older people with disability, providing guidance for long-term care plans. Based on the government-le...
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Article
Multidisciplinary and multiscale nanoscience research roadmap based on large scientific facilities
With the advancement of modern science and technology, large scientific facilities are increasingly oriented toward demand and application, and can be used for basic research as well as serving multiple discip...
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Article
Open AccessThe single-cell opioid responses in the context of HIV (SCORCH) consortium
Substance use disorders (SUD) and drug addiction are major threats to public health, impacting not only the millions of individuals struggling with SUD, but also surrounding families and communities. One of th...
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Article
Chinese Medicine Prolongs Overall Survival of Chinese Patients with Advanced Gastric Cancer: Treatment Pattern and Survival Analysis of a 20-Year Real-World Study
To describe the treatment patterns and survival status of advanced gastric cancer (AGC) in China in the past two decades, and objectively evaluate the impact of standardized Chinese medicine (CM) treatment on ...
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Article
Open AccessTargeting pro-inflammatory T cells as a novel therapeutic approach to potentially resolve atherosclerosis in humans
Atherosclerosis (AS), a leading cause of cardio-cerebrovascular disease worldwide, is driven by the accumulation of lipid contents and chronic inflammation. Traditional strategies primarily focus on lipid redu...
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Article
Review of 2D Bi2X3 (X = S, Se, Te): from preparation to photodetector
Detector has become an indispensable part of human beings. The increasing demand for photodetectors with high performance has promoted the research of novel materials. At the same time, with the development of...
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Article
Open AccessTwo-dimensional materials for future information technology: status and prospects
Over the past 70 years, the semiconductor industry has undergone transformative changes, largely driven by the miniaturization of devices and the integration of innovative structures and materials. Two-dimensi...
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Article
Open AccessMeasurement of t-channel production of single top quarks and antiquarks in pp collisions at 13 TeV using the full ATLAS Run 2 data sample
The production of single top quarks and top antiquarks via the t-channel exchange of a virtual W boson is measured in proton-proton collisions at a centre-of-mass energy of 13 TeV at the LHC using 140 fb−1 of ATL...
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Article
Open AccessSearch for new particles in final states with a boosted top quark and missing transverse momentum in proton-proton collisions at \( \sqrt{s} \) = 13 TeV with the ATLAS detector
A search for events with one top quark and missing transverse momentum in the final state is presented. The fully hadronic decay of the top quark is explored by selecting events with a reconstructed boosted to...
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Article
Open AccessP. gingivalis in oral-prostate axis exacerbates benign prostatic hyperplasia via IL-6/IL-6R pathway
Benign prostatic hyperplasia (BPH) is the most common disease in elderly men. There is increasing evidence that periodontitis increases the risk of BPH, but the specific mechanism remains unclear. This study a...
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Article
Open AccessElectron and photon efficiencies in LHC Run 2 with the ATLAS experiment
Precision measurements of electron reconstruction, identification, and isolation efficiencies and photon identification efficiencies are presented. They use the full Run 2 data sample collected by the ATLAS ex...
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Article
Open AccessSearch for electroweak production of supersymmetric particles in final states with two τ-leptons in \( \sqrt{s} \) = 13 TeV pp collisions with the ATLAS detector
Three searches for the direct production of τ-sleptons or charginos and neutralinos in final states with at least two hadronically decaying τ-leptons are presented. For chargino and neutralino production, decays ...
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Article
Open AccessMeasurement of the total and differential cross-sections of \( t\overline{t}W \) production in pp collisions at \( \sqrt{s} \) = 13 TeV with the ATLAS detector
Measurements of inclusive and differential production cross-sections of a top-quark-top-antiquark pair in association with a W boson ( ...
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Article
Open AccessATLAS Run 2 searches for electroweak production of supersymmetric particles interpreted within the pMSSM
A summary of the constraints from searches performed by the ATLAS collaboration for the electroweak production of charginos and neutralinos is presented. Results from eight separate ATLAS searches are consider...
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Article
Open AccessTest of CP-invariance of the Higgs boson in vector-boson fusion production and in its decay into four leptons
A search for CP violation in the decay kinematics and vector-boson fusion production of the Higgs boson is performed in the H → ZZ* → 4ℓ (ℓ = e, μ) decay channel. The results are based on proton-proton collision ...
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Article
Open AccessSpecific convulsions and brain damage in children hospitalized for Omicron BA.5 infection: an observational study using two cohorts
SARS-CoV-2 continues to mutate over time, and reports on children infected with Omicron BA.5 are limited. We aimed to analyze the specific symptoms of Omicron-infected children and to improve patient care.
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Article
Exfoliation Corrosion of As-Extruded Mg–1Li–1Ca: the Influence of the Superficial Layer
Exfoliation corrosion (EFC) has rarely been reported for wrought magnesium alloys. Enhanced EFC of the as-extruded Mg–1Li–1Ca alloy was observed after the removal of outermost fine-grained skins. The microstru...
