18,168 Result(s)
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Expression of Concern to: RAGE-binding S100A8/A9 promotes the migration and invasion of human breast cancer cells through actin polymerization and epithelial–mesenchymal transition
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Correction to: Gas6 Promotes Microglia Efferocytosis and Suppresses Inflammation Through Activating Axl/Rac1 Signaling in Subarachnoid Hemorrhage Mice
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Open AccessThe association of SOD and HsCRP with the efficacy of sulforaphane in schizophrenia patients with residual negative symptoms
Emerging evidence indicates a connection between oxidative stress, immune-inflammatory processes, and the negative symptoms of schizophrenia. In addition to possessing potent antioxidant and anti-inflammatory ...
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Open AccessDNA methylation age acceleration contributes to the development and prediction of non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) is prevalent in the aging society. Despite body weight reduction, the prevalence of NAFLD has been increasing with aging for unknown reasons. Here, we investigate the ...
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Open AccessSystematic Mendelian Randomization Exploring Druggable Genes for Hemorrhagic Strokes
Patients with hemorrhagic stroke have high rates of morbidity and mortality, and drugs for prevention are very limited. Mendelian randomization (MR) analysis can increase the success rate of drug development b...
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Open AccessExtending the detection limit: innovations in infrared quantum dot photodetectors reaching up to 18 μm
A regrowth method was used to synthesize large-sized colloidal quantum dots (CQDs). With the assistance of do** engineering, the synthesized CQD detectors demonstrate exceptional long-wavelength infrared det...
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Open AccessA case of Ph+ acute lymphoblastic leukemia and EGFR mutant lung adenocarcinoma synchronous overlap: may one TKI drug solve two diseases?
Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia (ALL) refers to ALL patients with t(9;22) cytogenetic abnormalities, accounting for about 25% of ALL. Lung adenocarcinoma (LUAD) is the most com...
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Open AccessEffect of transcranial direct current stimulation with concurrent cognitive performance targeting posterior parietal cortex vs prefrontal cortex on working memory in schizophrenia: a randomized clinical trial
Working memory deficits are linked to irregularities in the dorsolateral prefrontal cortex (DLPFC) and the posterior parietal cortex (PPC) in schizophrenia, effective intervention strategies are lacking. We ev...
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Open AccessMetagenomic comparison of intestinal microbiota between normal and liver fibrotic rhesus macaques (Macaca mulatta)
Liver fibrosis is an important pathological process in chronic liver disease and cirrhosis. Recent studies have found a close association between intestinal microbiota and the development of liver fibrosis. To...
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Open AccessRecent advances in 3D Gaussian splatting
The emergence of 3D Gaussian splatting (3DGS) has greatly accelerated rendering in novel view synthesis. Unlike neural implicit representations like neural radiance fields (NeRFs) that represent a 3D scene wit...
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Open AccessEffectiveness and pregnancy outcomes of ultrasound-indicated and physical examination-indicated cervical cerclage: a retrospective study from a single centre
Preterm birth (PTB) is the leading cause of neonatal morbidity and mortality worldwide, and cervical incompetence (CIC) is a significant contribution. Cervical cerclage (CC) is an effective obstetric intervent...
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Open AccessRelationships between nine neuropsychiatric disorders and cervical cancer: insights from genetics, causality and shared gene expression patterns
Neuropsychiatric disorders and cervical cancer exert substantial influences on women’s health. Furthermore, neuropsychiatric disorders frequently manifest as common symptoms in cancer patients, potentially inc...
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Open AccessYTHDC1 aggravates high glucose-induced retinal vascular endothelial cell injury via m6A modification of CDK6
Retinal vascular endothelial cell (RVECs) injury is a major cause of morbidity and mortality among the patients with diabetes. RVECs dysfunction is the predominant pathological manifestation of vascular compli...
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Open AccessThe association between heparin sensitivity index and postoperative blood loss in Chinese patients undergoing elective off-pump coronary artery bypass grafting: a single center retrospective study
The heparin sensitivity index (HSI) is closely associated with perioperative ischemic events and increased blood loss in cardiac surgery. Previous studies have produced conflicting results. Therefore, this stu...
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Open AccessPrevention of bone dehiscence associated with orthodontic tooth movement by prophylactic injection of bone anabolic agents in mice
Although bone dehiscence may occur during orthodontic tooth movement into the narrow alveolar ridge, a non-invasive prevention method is yet to be fully established. We show for the first time prevention of bo...
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Open AccessReal-time scheduling of power grid digital twin tasks in cloud via deep reinforcement learning
As energy demand continues to grow, it is crucial to integrate advanced technologies into power grids for better reliability and efficiency. Digital Twin (DT) technology plays a key role in this by using data ...
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Open AccessUnconventional posttranslational modification in innate immunity
Pattern recognition receptors (PRRs) play a crucial role in innate immunity, and a complex network tightly controls their signaling cascades to maintain immune homeostasis. Within the modification network, pos...
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Open AccessAI models predicting breast cancer distant metastasis using LightGBM with clinical blood markers and ultrasound maximum diameter
Breast cancer metastasis significantly impacts women's health globally. This study aimed to construct predictive models using clinical blood markers and ultrasound data to predict distant metastasis in breast ...
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Open AccessPlasma alpha B crystallin as potential biomarker for predicting pre-operative seizures in glioma
Glioma-associated epilepsy affects a significant proportion of glioma patients, contributing to disease progression and diminished survival rates. However, the lack of a reliable preoperative seizure predictor...
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Open AccessNicotinamide mitigates visceral leishmaniasis by regulating inflammatory response and enhancing lipid metabolism
Currently, treatment regimens for visceral leishmaniasis (VL) are limited because of the presence of numerous adverse effects. Nicotinamide, a readily available and cost-effective vitamin, has been widely ackn...
