102 Result(s)
within
**a Guoqing
Cancer Research
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Article
The Significance of the Expression of CyclinD1 and Ki67 Antigen in Nasopharyngeal Carcinoma
This study was conducted to detect the expression of cyclinD1 and Ki67 in nasopharyngeal carcinoma (NPC) and their correlation with the biological and prognosis. 56 cases of biopsy specimens of NPC which had ...
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Article
Comparing Gross Tumor Volume of Delineation between CT and MRI for Nasopharyngeal Carcinoma
Objective: To study the accuracy between CT and MRI in delineating gross tumor volume (GTV) of nasopharyngeal carcinoma (NPC) in making radiotherapy plan. Methods: The clinical data of 39 cases pathologically ...
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Article
Public Screening for Early Carcinoma of Gastric Cardia: Rule of Carcinogenetic Development Observed by Endoscopy
Objective: To study the rule of development of early cancer of gastric cardia in vivo in public screening. Methods: A prospective cohort study on gastric cardiac cancer was performed in the high incidence area...
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Expression of Cyclooxygenase-2 in Nasopharyngeal Carcinoma and Its Relation to Angiogenesis and Prognosis
Objective: The purpose of this study was to evaluate cyclooxygenase-2 (COX-2) expression in nasopharyngeal carcinoma (NPC) and its correlation with clinicopathologic features, angiogenesis, and prognosis. Meth...
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Article
Hypothalamic huntingtin-associated protein 1 as a mediator of feeding behavior
The hypothalamus responds to circulating leptin and insulin in the control of food intake and body weight. A number of neurotransmitters in the hypothalamus, including γ-aminobutyric acid (GABA), also have key...
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Article
Research on cell cycle retardation, apoptosis and the expression of antioncogene p57Kip2 by radioactive rays in nasopharyngeal carcinoma cell line in vitro
To study cell cycle retardation, apoptosis and the expression of antioncogene p57kip2 by radioactive rays in nasopharyngeal carcinoma cells.
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Article
LAMA4, highly expressed in human hepatocellular carcinoma from Chinese patients, is a novel marker of tumor invasion and metastasis
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in China. Hepatocarcinogenesis is correlated with a series of gene expression alteration. Here, we investigated LAMA4 gene expression in h...
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Article
A novel role for DYX1C1, a chaperone protein for both Hsp70 and Hsp90, in breast cancer
With three consecutive tetratricopeptide repeat (TPR) motifs at its C-terminus essential for neuronal migration, and a p23 domain at its N-terminus, DYX1C1 was the first gene proposed to have a role in develop...
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Article
The genome of the cucumber, Cucumis sativus L.
Jun Wang and colleagues report the genome sequence of the cucumber. The cucumber genome is the seventh plant genome sequence to be reported and was assembled with a combination of traditional Sanger and next-g...
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Article
Open AccessFirst-line treatment for chronic myeloid leukemia: dasatinib, nilotinib, or imatinib
Imatinib, a tyrosine kinase inhibitor (TKI) of BCR-ABL, was the standard first-line therapy for chronic myeloid leukemia (CML) for almost 10 years. Dasatinib and nilotinib, two newer drugs with higher potency ...
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Article
The efficacy of combination therapy using adeno-associated virus-TRAIL targeting to telomerase activity and cisplatin in a mice model of hepatocellular carcinoma
TNF-related apoptosis-inducing ligand (TRAIL) functions as a soluble cytokine and has been demonstrated significant antitumor activity against a variety of cancer cell lines without toxicity to most normal cel...
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An Evidence-based Perspective of Hedyotis Diffusa or Oldenlandia Diffusa (Spreading Hedyotis) for Cancer Patients
Hedyotis diffusa or Oldenlandia diffusa (spreading hedyotis) is one of the most commonly used anticancer herbs. Its clinical use has a history more than several thousand years. It contains flavones...
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Article
Clinical significance of EphA2 expression in squamous-cell carcinoma of the head and neck
EphA2 receptor tyrosine kinase is frequently overexpressed and functionally altered in a variety of human cancers. The study aimed to assess EphA2 expression and to explore its roles in squamous-cell carcinoma...
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Article
Cyclophilin A promotes human hepatocellular carcinoma cell metastasis via regulation of MMP3 and MMP9
Cyclophilin A (CypA) is a member of peptidyl prolyl isomerases (PPIases), which catalyze the cis/trans isomerization of prolyl peptide bonds on the NH-terminal side of Pro residues in peptide chains. Altered expr...
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Open AccessA meta-analysis of CAG (cytarabine, aclarubicin, G-CSF) regimen for the treatment of 1029 patients with acute myeloid leukemia and myelodysplastic syndrome
The regimen of cytarabine, aclarubicin and G-CSF (CAG) has been widely used in China and Japan for treatment of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). We searched literature on CAG be...
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Article
Open AccessLarge granular lymphocytosis with severe neutropenia following ipilimumab therapy for metastatic melanoma
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Article
Overexpression of tumor suppressor TSLC1 by a survivin-regulated oncolytic adenovirus significantly inhibits hepatocellular carcinoma growth
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide. Oncolytic viruses represent a promising therapeutic agent or vehicle to human cancers due to their ability of selectively ly...
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Open AccessComparison of safety and toxicity of liposomal doxorubicin vs. conventional anthracyclines: a meta-analysis
Liposomal formulations of anthracyclines appear to have favorable toxicity profile when compared with conventional anthracyclines in elderly, high risk cardiac patients and patients with prior use of anthracyc...
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Article
Analysis of cancer pain in hospitals in Bei**g, China
This study aimed to survey the characteristics and treatments of cancer pain in Bei**g hospitals, China.
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Article
Open AccessCD19: a biomarker for B cell development, lymphoma diagnosis and therapy
The human CD19 antigen is a 95 kd transmembrane glycoprotein belonging to the immunoglobulin superfamily. CD19 is classified as a type I transmembrane protein, with a single transmembrane domain, a cytoplasmic...
