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  1. Article

    Open Access

    Transcutaneous Electrical Acupoint Stimulation Combined with Moderate Sedation of Remimazolam Tosilate in Gastrointestinal Endoscopy: A Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial

    Further clinical validation is required to determine whether transcutaneous electrical acupoint stimulation (TEAS) can replace opioids and be used in combination with remimazolam for sedation during gastrointe...

    Jian-Han Xu, Hai-Ling Tan, Li-Na Zhang, Zan-Gong Zhou, Li Yuan in Pain and Therapy (2024)

  2. No Access

    Article

    Integrative analysis reveals that SLC38A1 promotes hepatocellular carcinoma development via PI3K/AKT/mTOR signaling via glutamine mediated energy metabolism

    Although hepatocellular carcinoma (HCC) is rather frequent, little is known about the molecular pathways underlying its development, progression, and prognosis. In the current study, we comprehensively analyze...

    Hua-guo Feng, Chuan-xin Wu, Guo-chao Zhong in Journal of Cancer Research and Clinical On… (2023)

  3. Article

    Open Access

    Value of Echocardiography and Cardiac Magnetic resonance in assessing left ventricular function in breast and gastric cancer patients after Anthracycline Chemotherapy

    Echocardiography (ECHO) and cardiac magnetic resonance imaging (MRI) are used to observe changes in the left ventricular structure in patients with breast and gastric cancer after 6 cycles of chemotherapy. Bas...

    Chao-long **, Xue-gong Shi, Ting-ting Wang, Hong-wen Li in BMC Cardiovascular Disorders (2023)

  4. Article

    Open Access

    Cross-sectional study of characteristics of body composition of 24,845 children and adolescents aged 3–17 years in Suzhou

    We aimed to analyze the characteristics of the body composition of children and adolescents aged 3–17 in Suzhou, China.

    Yan Zhao, **-xin Gong, Yi-ting Ji, **ao-yun Zhao, Lu He, Shi-zhong Cai in BMC Pediatrics (2023)

  5. Article

    Open Access

    Transcutaneous Electrical Acupoint Stimulation Improves Postoperative Sleep Quality in Patients Undergoing Laparoscopic Gastrointestinal Tumor Surgery: A Prospective, Randomized Controlled Trial

    This study was conducted to observe the effect of transcutaneous electrical acupoint stimulation (TEAS) on the postoperative sleep quality of patients undergoing gastrointestinal tumor surgery and to verify t...

    Jun Wang, Fei-Fei Lu, Miao-Miao Ge, Li-Wen Wang, Gang Wang in Pain and Therapy (2023)

  6. Article

    Open Access

    Serine-arginine protein kinase 1 (SRPK1) promotes EGFR-TKI resistance by enhancing GSK3β Ser9 autophosphorylation independent of its kinase activity in non-small-cell lung cancer

    Resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) is a major challenge for clinicians and patients with non-small cell lung cancer (NSCLC). Serine-arginine protein kinase ...

    **g-Qiang Huang, Ling-**n Duan, Qiu-Yu Liu, He-Feng Li, Ao-** Hu in Oncogene (2023)

  7. Article

    Open Access

    A pilot investigation of condylar position and asymmetry in patients with unilateral posterior scissors-bite malocclusion based on three-dimensional reconstructive imaging technique

    Unilateral posterior scissors-bite (uPSB) malocclusion is common clinically. This study aimed to investigate the condylar morphological alterations and condyle-fossa relationship in patients with uPSB, through...

    Chen-xi Li, **n **e, Mengjia Li, Zhong-cheng Gong in BMC Musculoskeletal Disorders (2023)

  8. Article

    Open Access

    Transarterial chemoembolization with PD-(L)1 inhibitors plus molecular targeted therapies for hepatocellular carcinoma (CHANCE001)

    There is considerable potential for integrating transarterial chemoembolization (TACE), programmed death-(ligand)1 (PD-[L]1) inhibitors, and molecular targeted treatments (MTT) in hepatocellular carcinoma (HCC...

    Hai-Dong Zhu, Hai-Liang Li, Ming-Sheng Huang in Signal Transduction and Targeted Therapy (2023)

  9. Article

    Open Access

    Correction: Human brucellosis and fever of unknown origin

    Zhi-guo Wu, Zhi-ying Song, Wei-xin Wang, Wen-na **, Di ** in BMC Infectious Diseases (2023)

  10. Article

    Open Access

    Human brucellosis and fever of unknown origin

    Human brucellosis has become one of the major public health problems in China, and increases atypical manifestations, such as fever of unknown origin (FUO), and misdiagnosis rates has complicated the diagnosis...

    Zhi-guo Wu, Zhi-ying Song, Wei-xin Wang, Wen-na **, Di ** in BMC Infectious Diseases (2022)

  11. Article

    Open Access

    Predictive value of early amplitude integrated electroencephalogram (aEEG) in sleep related problems in children with perinatal hypoxic-ischemia (HIE)

    While great attention has been paid to motor and cognitive impairments in children with neonatal Hypoxic-Ischemic Encephalopathy (HIE), sleep related circadian rhythm problems, although commonly present, are o...

    Qiuyan Tian, Yizhi Pan, Zheng Zhang, Mei Li, Li-xiao Xu, Min Gong in BMC Pediatrics (2021)

  12. Article

    Open Access

    Early Diagnostic Biomarkers of Sepsis for Patients with Acute-on-Chronic Liver Failure: A Multicenter Study

    Sepsis is a complication in acute-on-chronic liver failure (ACLF) patients associated with high rates of mortality and morbidity. Early diagnosis of sepsis in ACLF patients can improve prognosis. This study ai...

    Jun Chen, Ze-Bing Huang, Hai Li, **n Zheng, **-Jun Chen in Infectious Diseases and Therapy (2021)

  13. Article

    Open Access

    Novel insights into stress-induced susceptibility to influenza: corticosterone impacts interferon-β responses by Mfn2-mediated ubiquitin degradation of MAVS

    Although stress has been known to increase the susceptibility of pathogen infection, the underlying mechanism remains elusive. In this study, we reported that restraint stress dramatically enhanced the morbidi...

    Zhuo Luo, Li-Fang Liu, Ying-Nan Jiang in Signal Transduction and Targeted Therapy (2020)

  14. Article

    Open Access

    Final adult height of children with idiopathic short stature: a multicenter study on GH therapy alone started during peri-puberty

    To evaluate the efficacy of GH in improving FAH in ISS children in a multicenter study.

    Di Wu, Rui-min Chen, Shao-ke Chen, Ge-li Liu, Lin-qi Chen, Yu Yang in BMC Pediatrics (2020)

  15. Article

    Open Access

    AMPKα1 confers survival advantage of colorectal cancer cells under metabolic stress by promoting redox balance through the regulation of glutathione reductase phosphorylation

    Patients with stage II or III colorectal cancer (CRC) exhibit various clinical outcomes after radical treatments. The 5-year survival rate was between 50 and 87%. However, the underlying mechanisms of the vari...

    Ying-Nan Wang, Yun-**n Lu, Jie Liu, Ying **, Hui-Chang Bi, Qi Zhao in Oncogene (2020)

  16. Article

    Open Access

    The values of applying classification and counts of white blood cells to the prognostic evaluation of resectable gastric cancers

    The classifications and counts of white blood cells (WBCs) have been proved to be able to be used as prognostic markers in cancer cases. The present study investigated the potential values of the classificatio...

    Yin-Ling Wang, **n-**n Ge, Yi Wang, Meng-Dan Xu, Fei-Ran Gong in BMC Gastroenterology (2018)

  17. No Access

    Article

    Safety of intraoperative chemotherapy with 5-FU for colorectal cancer patients receiving curative resection: a randomized, multicenter, prospective, phase III IOCCRC trial (IOCCRC)

    The safety and efficacy of intraoperative chemotherapy in colorectal cancer have not yet been extensively investigated. This randomized control trial was designed to compare the safety and efficacy of intraope...

    Rong-xin Zhang, Jun-zhong Lin, Jian Lei in Journal of Cancer Research and Clinical On… (2017)

  18. Article

    Strain/strain rate imaging of impaired left atrial function in patients with metabolic syndrome

    Left ventricular (LV) dysfunction has been demonstrated in patients with metabolic syndrome (MetS). However, alterations in left atrial (LA) function in MetS are unknown. We aimed to use strain/strain rate (SR...

    Ning-ning Fang, Dong-xin Sui, **-gui Yu, Hui-** Gong in Hypertension Research (2015)

  19. Article

    Open Access

    The role of high mobility group box chromosomal protein 1 expression in the differential diagnosis of hepatic actinomycosis: a case report

    Primary hepatic actinomycosis is a rare disease, but is important in the differential diagnosis of hepatoma in endemic areas. As high mobility group box chromosomal protein 1 plays an important role in the pat...

    Chuan-**n Wu, Hui Guo, Jian-** Gong, Qi Liu, Hang Sun in Journal of Medical Case Reports (2013)

  20. Article

    Excess nicotinamide inhibits methylation-mediated degradation of catecholamines in normotensives and hypertensives

    Nicotinamide and catecholamines are both degraded by S-adenosylmethionine-dependent methylation. Whether excess nicotinamide affects the degradation of catecholamines is unknown. The aim of this study was to inve...

    Wu-** Sun, Da Li, Yong-Zhi Lun, **ao-Jie Gong, Shen-**a Sun in Hypertension Research (2012)

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