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Article
Endogenous attention enhances contrast appearance regardless of stimulus contrast
There has been enduring debate on how attention alters contrast appearance. Recent research indicates that exogenous attention enhances contrast appearance for low-contrast stimuli but attenuates it for high-c...
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Article
TRPC6 Knockout Alleviates Renal Fibrosis through PI3K/AKT/GSK3B Pathway
Renal fibrosis is the ultimate pathway of various forms of acute and chronic kidney damage. Notably, the knockout of transient receptor potential channel 6 (TRPC6) has shown promise in alleviating renal fibros...
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Article
Open AccessAssociation between pretreatment emotional distress and immune checkpoint inhibitor response in non-small-cell lung cancer
Emotional distress (ED), commonly characterized by symptoms of depression and/or anxiety, is prevalent in patients with cancer. Preclinical studies suggest that ED can impair antitumor immune responses, but fe...
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Article
Light-induced stepped thermal relaxation in a Hofmann-type metal-organic framework
Spin-crossover (SCO) materials with light-induced multistability have potential applications in multi-addressable opto-magnetic memory devices and multiple switches. Here, we reported a three-dimensional Hofma...
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Article
Open AccessPreoperative chemoradiotherapy in older patients with rectal cancer guided by comprehensive geriatric assessment within a multidisciplinary team—a multicenter phase II trial
The purpose of this study was to evaluate the safety and efficacy of preoperative concurrent chemoradiotherapy (preCRT) for locally advanced rectal cancer in older people who were classified as “fit” by compre...
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Article
MiR-210-3p enhances intermittent hypoxia-induced tumor progression via inhibition of E2F3
Intermittent hypoxia (IH) is a hallmark of obstructive sleep apnea (OSA), which is related to tumorigenesis and progression. Although micro-ribonucleic acid-210-3p (miR-210-3p) is correlated with hypoxia-induc...
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Article
Orientation controlled photogenerated carriers on self-supporting CdS/Ni3S2 paper toward photocatalytic hydrogen evolution and biomass upgrading
The appropriate regulation of band structure is an effective strategy in constructing efficient photocatalytic systems. Present photocatalytic system mainly employs powder photocatalysts, which makes their rec...
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Article
Cretaceous integrative stratigraphy, biotas, and paleogeographical evolution of the Qinghai-Tibetan Plateau and its surrounding areas
The Cretaceous Period is a vital time interval in deciphering the evolutionary history of the Neo-Tethys Ocean and the convergence of different plates and blocks across the Qinghai-Tibetan Plateau. A detailed ...
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Article
Hierarchical V3S4/C nanofibers with fast kinetics for superior alkali metal batteries
Owing to the numerous benefits, including low cost and great theoretical capacity, V3S4 has been a research hotspot for Li+/Na+/K+ storage. Nonetheless, the V3S4 electrode with long cycling stability and high spe...
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Article
A multicenter propensity score analysis of significance of hepatic resection type for early-stage hepatocellular carcinoma
The impact of hepatic resection type on long-term oncological prognosis of patients with early-stage hepatocellular carcinoma (HCC) has not been systematically investigated. We sought to determine risk factors...
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Article
Diallyl disulfide synergizes with melphalan to increase apoptosis and DNA damage through elevation of reactive oxygen species in multiple myeloma cells
Diallyl disulfide (DADS), one of the main components of garlic, is well known to have anticancer effects on multiple cancers. However, its efficacy in treating multiple myeloma (MM) is yet to be determined. We...
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Article
Open AccessThe impact of preoperative biliary drainage on postoperative healthcare-associated infections and clinical outcomes following pancreaticoduodenectomy: a ten-year retrospective analysis
Pancreaticoduodenectomy (PD) is a complex procedure and easily accompanied by healthcare-associated infections (HAIs). This study aimed to assess the impact of PBD on postoperative infections and clinical outc...
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Article
Inferring Causal Relationships Between Metabolites and Polycystic Ovary Syndrome Using Summary Statistics from Genome‑Wide Association Studies
Polycystic ovary syndrome (PCOS) is a disorder characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovarian morphology. Previous studies have suggested that metabolites may play a pivotal m...
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Article
Open AccessGlobal fungal-host interactome map** identifies host targets of candidalysin
Candidalysin, a cytolytic peptide toxin secreted by the human fungal pathogen Candida albicans, is critical for fungal pathogenesis. Yet, its intracellular targets have not been extensively mapped. Here, we perfo...
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Article
Open AccessCorrection to: Expert consensus on the diagnosis, treatment, and prevention of respiratory syncytial virus infections in children
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Article
Nondestructive technique for identifying nuclides using neutron resonance transmission analysis at CSNS Back-n
Nondestructive and noninvasive neutron assays are essential applications of neutron techniques. Neutron resonance transmission analysis (NRTA) is a powerful nondestructive method for investigating the elementa...
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Article
Open AccessBereaved parents’ perceptions of memory making: a qualitative meta-synthesis
This study aims to investigate the experiences of parents who have experienced bereavement in their efforts to preserve memories of their deceased child.
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Article
Carvedilol induces pyroptosis through NLRP3-caspase1-ASC inflammasome by nuclear migration of NF-κB in prostate cancer models
Pyroptosis is an inflammatory type of programmed cell death, and could overcome the drug-resistance induced by anti-apoptotic effect of cancers. Carvedilol (CVL), a β-adrenergic receptors antagonist, has shown...
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Article
Open AccessEfficacy of Qingpeng ointment (a Tibetan medicine) for acute gouty arthritis: a multi-center, randomized, double-blind, placebo-controlled trial
This study aims to assess the efficacy and safety of Qingpeng ointment (QPO), a Tibetan medicine for alleviating symptoms in individuals with acute gouty arthritis (AGA).
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Article
Physiological tolerance of black locust (Robinia pseudoacacia L.) and changes of rhizospheric bacterial communities in response to Cd and Pb in the contaminated soil
Woody plants possess great potential for phytoremediation of heavy metal-contaminated soil. A pot trial was conducted to study growth, physiological response, and Cd and Pb uptake and distribution in black loc...
