847 Result(s)
within
**-ling Zhang
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessLeukocyte immunoglobulin-like receptor B1 (LILRB1) protects human multiple myeloma cells from ferroptosis by maintaining cholesterol homeostasis
Multiple myeloma (MM) is a hematologic malignancy characterized by uncontrolled proliferation of plasma cells in the bone marrow. MM patients with aggressive progression have poor survival, emphasizing the urg...
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Open AccessSingle-cell RNA sequencing reveals special basal cells and fibroblasts in idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is the most predominant type of idiopathic interstitial pneumonia and has an increasing incidence, poor prognosis, and unclear pathogenesis. In order to investigate the mole...
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Open AccessDeoxycholic acid inducing chronic atrophic gastritis with colonic mucosal lesion correlated to mucosal immune dysfunction in rats
The present study aimed to explore the underlying mechanism of bile reflux-inducing chronic atrophic gastritis (CAG) with colonic mucosal lesion. The rat model of CAG with colonic mucosal lesion was induced by...
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Open AccessThe role and mechanism of action of miR-483-3p in mediating the effects of IGF-1 on human renal tubular epithelial cells induced by high glucose
This study aimed to elucidate the influence of miR-483-3p on human renal tubular epithelial cells (HK-2) under high glucose conditions and to understand its mechanism. Human proximal tubular epithelial cells (...
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Open AccessStable peptide-assembled nanozyme mimicking dual antifungal actions
Natural antimicrobial peptides (AMPs) and enzymes (AMEs) are promising non-antibiotic candidates against antimicrobial resistance but suffer from low efficiency and poor stability. Here, we develop peptide nan...
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Open AccessA retrospective study on the impact of radiotherapy on the survival outcomes of small cell lung cancer patients based on the SEER database
Small cell lung cancer (SCLC) patients exhibit significant heterogeneity in tumor burden, physical condition, and responses to initial treatment. This diversity in treatment responses can result in varying tre...
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Open AccessGiant nonlinear Hall and wireless rectification effects at room temperature in the elemental semiconductor tellurium
The second-order nonlinear Hall effect (NLHE) in non-centrosymmetric materials has recently drawn intense interest, since its inherent rectification could enable various device applications such as energy harv...
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Open AccessSuperporous sponge prepared by secondary network compaction with enhanced permeability and mechanical properties for non-compressible hemostasis in pigs
Develo** superporous hemostatic sponges with simultaneously enhanced permeability and mechanical properties remains challenging but highly desirable to achieve rapid hemostasis for non-compressible hemorrhag...
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Open AccessEvaluation of agricultural non-point source pollution using an in-situ and automated photochemical flow analysis system
Off-line leachate collection from agricultural landscapes cannot guarantee precise evaluation of agricultural non-point source (ANPS) due to geospatial variations, time, and transportation from the field to th...
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Open AccessA cocktail nanovaccine targeting key entry glycoproteins elicits high neutralizing antibody levels against EBV infection
Epstein-Barr virus (EBV) infects more than 95% of adults worldwide and is closely associated with various malignancies. Considering the complex life cycle of EBV, develo** vaccines targeting key entry glycop...
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Open AccessAugmented microglial endoplasmic reticulum-mitochondria contacts mediate depression-like behavior in mice induced by chronic social defeat stress
Extracellular ATP (eATP) signaling through the P2X7 receptor pathway is widely believed to trigger NLRP3 inflammasome assembly in microglia, potentially contributing to depression. However, the cellular stress...
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Open AccessCholesterol efflux from C1QB-expressing macrophages is associated with resistance to chimeric antigen receptor T cell therapy in primary refractory diffuse large B cell lymphoma
Chimeric antigen receptor T (CAR-T) cell therapy has demonstrated promising efficacy in early trials for relapsed/refractory diffuse large B cell lymphoma (DLBCL). However, its efficacy in treating primary ref...
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Open AccessMYG1 drives glycolysis and colorectal cancer development through nuclear-mitochondrial collaboration
Metabolic remodeling is a strategy for tumor survival under stress. However, the molecular mechanisms during the metabolic remodeling of colorectal cancer (CRC) remain unclear. Melanocyte proliferating gene 1 ...
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Open AccessCovalently bridging graphene edges for improving mechanical and electrical properties of fibers
Assembling graphene sheets into macroscopic fibers with graphitic layers uniaxially aligned along the fiber axis is of both fundamental and technological importance. However, the optimal performance of graphen...
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Open AccessReal-time predictive model of extrauterine growth retardation in preterm infants with gestational age less than 32 weeks
The aim of this study was to develop a real-time risk prediction model for extrauterine growth retardation (EUGR). A total of 2514 very preterm infants were allocated into a training set and an external valida...
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Open AccessMolecular ferroelectric with low-magnetic-field magnetoelectricity at room temperature
Magnetoelectric materials, which encompass coupled magnetic and electric polarizabilities within a single phase, hold great promises for magnetic controlled electronic components or electric-field controlled s...
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Open AccessEfficacy of an herbal formula Guixiong Yimu San in preventing retained placenta and improving reproductive performance in cows
Retained placenta is a common health issue, and appropriate prevention strategies are effective in postpartum health management. This study aimed to evaluate whether early intervention using GYS can prevent re...
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Dimerization and antidepressant recognition at noradrenaline transporter
The noradrenaline transporter has a pivotal role in regulating neurotransmitter balance and is crucial for normal physiology and neurobiology1. Dysfunction of noradrenaline transporter has been implicated in nume...
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Open AccessNutrient levels control root growth responses to high ambient temperature in plants
Global warming will lead to significantly increased temperatures on earth. Plants respond to high ambient temperature with altered developmental and growth programs, termed thermomorphogenesis. Here we show th...
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Open AccessIn-situ observation of silk nanofibril assembly via graphene plasmonic infrared sensor
Silk nanofibrils (SNFs), the fundamental building blocks of silk fibers, endow them with exceptional properties. However, the intricate mechanism governing SNF assembly, a process involving both protein confor...
