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Article
Open AccessBAIAP2 exhibits association to childhood ADHD especially predominantly inattentive subtype in Chinese Han subjects
Attention-deficit/hyperactivity disorder (ADHD) is a common chronic neurodevelopmental disorder with a high heritability. Much evidence of hemisphere asymmetry has been found for ADHD probands from behavioral ...
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Article
Open AccessAutism-associated gene Dlgap2 mutant mice demonstrate exacerbated aggressive behaviors and orbitofrontal cortex deficits
As elegant structures designed for neural communication, synapses are the building bricks of our mental functions. Recently, many studies have pointed out that synaptic protein-associated mutations may lead to...
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Article
Open AccessPrior Visual Experience Modulates Learning of Sound Localization Among Blind Individuals
Cross-modal learning requires the use of information from different sensory modalities. This study investigated how the prior visual experience of late blind individuals could modulate neural processes associa...
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Article
Open AccessResveratrol ameliorates prenatal progestin exposure-induced autism-like behavior through ERβ activation
Recent literatures indicate that maternal hormone exposure is a risk factor for autism spectrum disorder (ASD). We hypothesize that prenatal progestin exposure may counteract the neuroprotective effect of estr...
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Article
Open AccessInherited and multiple de novo mutations in autism/developmental delay risk genes suggest a multifactorial model
We previously performed targeted sequencing of autism risk genes in probands from the Autism Clinical and Genetic Resources in China (ACGC) (phase I). Here, we expand this analysis to a larger cohort of patien...
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Article
Open AccessAn integrative analysis of genome-wide association study and regulatory SNP annotation datasets identified candidate genes for bipolar disorder
Bipolar disorder (BD) is a complex mood disorder. The genetic mechanism of BD remains largely unknown.
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Article
Open AccessFunctional relationships between recessive inherited genes and genes with de novo variants in autism spectrum disorder
Both de novo variants and recessive inherited variants were associated with autism spectrum disorder (ASD). This study aimed to use exome data to prioritize recessive inherited genes (RIGs) with biallelically ...
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Article
Open AccessRisk factors for sleep disorders in patients undergoing peritoneal dialysis
Sleep disorders in patients with end-stage renal disease are common but have rarely been reported in previous studies. Therefore, we examined the prevalence of sleep disorders and the risk factors for declinin...
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Article
Open AccessConvergent and divergent gray matter volume abnormalities in unaffected first-degree relatives and ultra-high risk individuals of schizophrenia
High-risk populations of schizophrenia can be mainly identified as genetic high-risk based on putative endophenotypes or ultra-high-risk (UHR) based on clinically manifested symptoms. Previous studies have con...
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Article
A visualized MAC nomogram online predicts the risk of three-month mortality in Chinese elderly aneurysmal subarachnoid hemorrhage patients undergoing endovascular coiling
Aneurysmal subarachnoid hemorrhage (aSAH) is an aggressive disease with higher mortality rate in the elderly population. Unfortunately, the previous models for predicting clinical prognosis are still not accur...
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Article
Open AccessSpecific brain imaging alterations underlying autistic traits in children with attention-deficit/hyperactivity disorder
Autistic traits (ATs) are frequently reported in children with Attention-Deficit/Hyperactivity Disorder (ADHD). This study aimed to examine ATs in children with ADHD from both behavioral and neuroimaging persp...
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Article
Open AccessInhibition of astroglial hemichannels ameliorates infrasonic noise induced short-term learning and memory impairment
As a kind of environmental noise, infrasonic noise has negative effects on various human organs. To date, research has shown that infrasound impairs cognitive function, especially the ability for learning and ...
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Article
Open AccessSociodemographic, clinical and treatment characteristics of current rapid-cycling bipolar disorder: a multicenter Chinese study
Rapid cycling bipolar disorder (RCBD), characterized by four or more episodes per year, is a complex subtype of bipolar disorder (BD) with poorly understood characteristics.
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Article
Open AccessPost-sepsis psychiatric disorder: Pathophysiology, prevention, and treatment
Post-sepsis psychiatric disorder, encompassing anxiety, depression, post-traumatic stress disorder and delirium, is a highly prevalent complication secondary to sepsis, resulting in a marked increase in long-t...