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20,409 Result(s)
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Article
Stress, Vascular Smooth Muscle Cell Phenotype and Atherosclerosis: Novel Insight into Smooth Muscle Cell Phenotypic Transition in Atherosclerosis
Our work is to establish more distinct association between specific stress and vascular smooth muscle cells (VSMCs) phenotypes to alleviate atherosclerotic plaque burden and delay atherosclerosis (AS) progress...
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Oxidation resistant low-alloyed Ti alloys with good ductility
Oxidation resistance enhancement of pure Ti often comes at the cost of reduced ductility, which is frequently the problem through alloying with sole Al, Si, W, Mo and B. To overcome the short coming of single ...
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Article
Cimifugin Mechanism of Action from Saposhnikovia divaricata in the Treatment of Atopic Dermatitis
The present study aimed to explore the mechanism of action of cimifugin, the primary active ingredient in Saposhnikovia divaricata (Turcz.) Schischk., Apiaceae, in treating atopic dermatitis. BALB/c mice were gro...
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Article
miR-221-3p is upregulated in acute pulmonary embolism complicated with pulmonary hypertension and promotes pulmonary arterial smooth muscle cells proliferation and migration by inhibiting PTEN
Pulmonary arterial smooth muscle cells (PASMCs) functions are associated with the pathogenesis of pulmonary hypertension (PH) which is a life-threatening complication of acute pulmonary embolism (APE). This st...
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Article
Giant Topological Bandgap and Rashba Effect in Decorated Plumbene: A First-Principles Study
Materials with large Rashba spin splitting (RSS) and quantum spin Hall effect (QSHE) are extremely important in spintronic device applications. Based on first-principles calculations, we present H–Pb–OH, a two...
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Article
Effect of Bricks-and-Mortar Architecture on Fracture Behavior of SiCp/Al Composite: A Finite Element Analysis
The metal-matrix composites (MMCs) with biomimetic bricks-and-mortar architectures have been experimentally demonstrated to exhibit excellent strength-ductility match. Here, biomimetic bricks-and-mortar archit...
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Raddeanin A Protects the BRB Through Inhibiting Inflammation and Apoptosis in the Retina of Alzheimer’s Disease
Neuroinflammation and endothelial cell apoptosis are prominent features of blood–brain barrier (BBB) disruption, which have been described in Alzheimer’s disease (AD) and can predict cognitive decline. Recent ...
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Open AccessLipoprotein (a)-Related Inflammatory Imbalance: A Novel Horizon for the Development of Atherosclerosis
The primary objective of this review is to explore the pathophysiological roles and clinical implications of lipoprotein(a) [Lp(a)] in the context of atherosclerotic cardiovascular disease (ASCVD). We seek to ...
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Article
Arbitrary topological charge vortex beams from carbon dots random lasers
Vortex beams have attracted great attention due to their promising applications in the fields of high-capacity optical communication, optical micromanipulation, and quantum information processing. Here, we dem...
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Article
Open AccessMiR-425-5p suppression of Crebzf regulates oocyte aging via chromatin modification
Female infertility due to declining oocyte quality with age remains a significant challenge for patients and physicians, despite extensive research efforts. Recent studies suggest that microRNAs (miRNAs), whic...
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Article
Distribution Law of Occurrence State and Content Prediction of Deep CBM: A Case Study in the Ordos Basin, China
The deep coalbed methane (CBM) resources in the Ordos Basin are enormous, and their exploration and development breakthrough are among the critical ways to improve CBM production in China. The occurrence state...
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Open AccessThe association of SOD and HsCRP with the efficacy of sulforaphane in schizophrenia patients with residual negative symptoms
Emerging evidence indicates a connection between oxidative stress, immune-inflammatory processes, and the negative symptoms of schizophrenia. In addition to possessing potent antioxidant and anti-inflammatory ...
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Article
Matrix-variate generalized linear model with measurement error
Matrix-variate generalized linear model (mvGLM) has been investigated successfully under the framework of tensor generalized linear model, because matrix-form data can be regarded as a specific tensor (2-dimen...
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Article
Softmax-Free Linear Transformers
Vision transformers (ViTs) have pushed the state-of-the-art for visual perception tasks. The self-attention mechanism underpinning the strength of ViTs has a quadratic complexity in both computation and memory...
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Association Between Multiple Metal(loid)s Exposure and Blood Lipid Levels: Evidence from a Cross-Sectional Study of Southeastern China
Exposure to essential and toxic metals occurs simultaneously as a mixture in real-life. However, there is no consensus regarding the effects of co-exposure to multiple metal(loid)s (designated hereafter metals...
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Open AccessEffect of temperature on tribofilm growth and the lubrication of the piston ring-cylinder liner system in two-stroke marine engines
This study is an optimized extension based on the authors’ previous research on the tribo-chemical reaction under constant temperature field of two-stroke internal combustion engines (ICEs). It establishes a c...
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Article
Predefined-time adaptive consensus control for nonlinear multi-agent systems with input quantization and actuator faults
Predefined-time control has experienced substantial advancements in recent years. Nevertheless, the current technology has not achieved widespread adoption in nonlinear multi-agent systems (NMASs), and signifi...
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Open AccessA new kinematic model for revolute clearance joints with noncircular bushing and pin in planar multibody systems
Due to manufacturing error and wear, the profiles of bushing and pin in revolute clearance joints are usually non-circular, while traditional kinematic models for revolute clearance joints generally assume a c...
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Deep Learning Technique for Human Parsing: A Survey and Outlook
Human parsing aims to partition humans in image or video into multiple pixel-level semantic parts. In the last decade, it has gained significantly increased interest in the computer vision community and has be...
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Open AccessDynamics of single-nuclei transcriptomic profiling of adipose tissue from diverse anatomical locations during mouse aging process
Adipose tissue plays critical roles in an individual’s aging process. In this research, we use single-nucleus RNA sequencing to create highly detailed transcriptional maps of subcutaneous adipose tissue and vi...