6 Result(s)
within
**-fang Zhai
Cancer Research
Health Promotion and Disease Prevention
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Article
Open AccessFailure pattern and suggestions for target volume delineation of carcinoma showing thymus-like differentiation treated with intensity-modulated radiotherapy
To review our long-term clinical experience, analyze the failure patterns, and give suggestions for target volume delineation of carcinoma showing thymus-like differentiation (CASTLE) treated with intensity-mo...
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Article
Open AccessDiscovery of a novel ALK/ROS1/FAK inhibitor, APG-2449, in preclinical non-small cell lung cancer and ovarian cancer models
Tyrosine kinase inhibitors (TKIs) are mainstays of cancer treatment. However, their clinical benefits are often constrained by acquired resistance. To overcome such outcomes, we have rationally engineered APG-...
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Article
Open AccessOncoPDSS: an evidence-based clinical decision support system for oncology pharmacotherapy at the individual level
Precision oncology pharmacotherapy relies on precise patient-specific alterations that impact drug responses. Due to rapid advances in clinical tumor sequencing, an urgent need exists for a clinical support to...
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Article
Open AccessUpregulation of NETO2 expression correlates with tumor progression and poor prognosis in colorectal carcinoma
Neuropilin and tolloid-like 2 (NETO2) has been found to be overexpressed in different human cancers, but its expression pattern and clinical relevance in colorectal carcinoma (CRC) remains unknown.
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Article
Open AccessSerine threonine tyrosine kinase 1 is a potential prognostic marker in colorectal cancer
Aberrant expression of serine threonine tyrosine kinase 1 (STYK1) has been reported in several human malignancies including colorectal cancer (CRC). However, the prognostic significance of STYK1 expression in ...
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Article
Open AccessPrognostic value of carbonic anhydrase VII expression in colorectal carcinoma
Carbonic anhydrases (CAs) have been implicated in the pathogenesis of human cancers. Carbonic anhydrase VII (CA7), a member of the CA gene family, was recently demonstrated to be expressed in several human tis...
