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  1. Article

    Open Access

    Crosstalk among proximal tubular cells, macrophages, and fibroblasts in acute kidney injury: single-cell profiling from the perspective of ferroptosis

    The link between ferroptosis, a form of cell death mediated by iron and acute kidney injury (AKI) is recently gaining widespread attention. However, the mechanism of the crosstalk between cells in the pathogen...

    Yulin Wang, Ziyan Shen, Shaocong Mo, Han Zhang, **g Chen, Cheng Zhu in Human Cell (2024)

  2. Article

    Open Access

    Exome sequencing and genome-wide association analyses unveils the genetic predisposition in hydroxychloroquine retinopathy

    To unveil the candidate susceptibility genes in chloroquine/hydroxychloroquine (CQ/HCQ) retinopathy using whole exome sequencing (WES) and genome-wide association study (GWAS).

    Hsun-I Chiu, Hui-Chen Cheng, Chih-Chiau Wu, Shih-Jen Chen, De-Kuang Hwang in Eye (2024)

  3. Article

    Open Access

    Enabling the design of surgical instruments for under-resourced patients through metal additive manufacturing: ulnar shortening osteotomy as an example

    Ulnar shortening osteotomy (USO) has demonstrated good outcomes for patients with ulnar impaction syndrome. To minimize complications such as non-union, precise osteotomy and firm fixation are warranted. Despi...

    Kuan-Lin Chen, Cheng-Yu Yin, Hui-Kuang Huang, Yi-Chao Huang in 3D Printing in Medicine (2024)

  4. Article

    Open Access

    Shock index to predict outcomes in patients with trauma following traffic collisions: a retrospective cohort study

    Taiwan, which has a rate of high vehicle ownership, faces significant challenges in managing trauma caused by traffic collisions. In Taiwan, traffic collisions contribute significantly to morbidity and mortali...

    Te-Kai Liao, Chung-Han Ho, Ying-Jia Lin in European Journal of Trauma and Emergency S… (2024)

  5. Article

    Open Access

    Risk factors for renal outcomes in children with antineutrophil cytoplasmic antibody-associated vasculitis: a nationwide retrospective study in China

    Pediatric antineutrophil cytoplasmic antibody-associated vasculitis (AAV) is a life-threatening systemic vasculitis featured by liability to renal involvement. However, there are few studies on the risk factor...

    Li-Wen Tan, Jun-Li Wan, Chun-Hua Zhu, Hong Xu, Zheng-Kun **a in World Journal of Pediatrics (2024)

  6. No Access

    Article

    PELE scores: pelvic X-ray landmark detection with pelvis extraction and enhancement

    Pelvic X-ray (PXR) is widely utilized in clinical decision-making associated with the pelvis, the lower part of the trunk that supports and balances the trunk. In particular, PXR-based landmark detection facil...

    Zhen Huang, Han Li, Shitong Shao, Heqin Zhu in International Journal of Computer Assisted… (2024)

  7. Article

    Open Access

    The impact of preoperative nutritional status on postoperative outcomes: an insight from Geriatric Nutritional Risk Index in elderly pancreaticoduodenectomy patients

    Malnutrition is not uncommon among the elderly undergoing pancreatoduodenectomy (PD) and is related to increased complications. Previous studies have shown that the Geriatric Nutritional Risk Index (GNRI) pred...

    Teng-Yuan Hou, Yu-Hung Lin, Yueh-Wei Liu, Yu-Yin Liu, Wei-Feng Li in BMC Surgery (2024)

  8. Article

    Open Access

    An algorithm for simplified hepatitis C virus treatment with non-specialist care based on nation-wide data from Taiwan

    Both European Association for the Study of the Liver (EASL) and American Association for the Study of Liver Diseases and the Infectious Diseases Society of America (AASLD-IDSA) guidelines recommend simplified ...

    Ming-Lung Yu, Chi‐Ming Tai, Lein-Ray Mo, Hsing-Tao Kuo in Hepatology International (2024)

  9. No Access

    Article

    ASO Author Reflections: Advancements in Laparoscopic Parenchyma-Sparing Liver Resection: Autologous Peritoneal Patch for Middle Hepatic Vein Reconstruction in Colorectal Liver Metastasis

    Wei-Jung Chang MD, Chia-Bang Chen MD, Yun-Tzu Chang MD in Annals of Surgical Oncology (2024)

  10. Article

    Open Access

    Neutrophil lncRNA ZNF100-6:2 is a potential diagnostic marker for active pulmonary tuberculosis

    Active pulmonary tuberculosis (PTB) poses challenges in rapid diagnosis within complex clinical conditions. Given the close association between neutrophils and tuberculosis, we explored differentially expresse...

    Shuying Huang, **uhua Kang, Zhenguo Zeng in European Journal of Medical Research (2024)

  11. No Access

    Article

    Prevalent landscape of tumor genomic alterations of luminal B1 breast cancers using a comprehensive genomic profiling assay in Taiwan

    The human epidermal growth factor receptor 2 (HER2) negative luminal B1 subtype of breast cancer has been reported with a poorer outcome than luminal A in recent studies. This study aimed to investigate the mo...

    Bo-Fang Chen, Yi-Fang Tsai, Pei-Ju Lien, Yen-Shu Lin, Chin-Jung Feng in Breast Cancer (2024)

  12. Article

    Novel Use of the Falciform Ligament for MHV Reconstruction During Laparoscopic Hepatectomy of Colorectal Liver Metastasis

    Laparoscopic hepatectomy (LH) with oncological R0 resection combined with systemic therapy offers the best chance of cure for colorectal liver metastasis. However, tumors in vicinity of major hepatic veins req...

    Wei-Jung Chang MD, Chia-Bang Chen MD, Yun-Tzu Chang MD in Annals of Surgical Oncology (2024)

  13. Article

    Open Access

    Collagen patch cover facilitates recovery of bowel function after laparoscopic colectomy

    Numerous factors can influence bowel movement recovery and anastomotic healing in colorectal surgery, and poor healing can lead to severe complications and increased medical expenses. Collagen patch cover (CPC...

    Pin-Yang Huang, Meng-Che Tsai, Kee-Thai Kiu, Min-Hsuan Yen, Tung-Cheng Chang in BMC Surgery (2024)

  14. No Access

    Article

    Severity of fatty liver is highly correlated with the risk of hypertension and diabetes: a cross-sectional and longitudinal cohort study

    Fatty liver disease (FLD) is associated with several metabolic derangements. We conducted a retrospective cross-sectional and longitudinal study to evaluate the role of FL severity in the risk of new-onset and...

    Chin-I. Shih, Kuan-Ta Wu, Meng-Hsuan Hsieh, Jeng-Fu Yang in Hepatology International (2024)

  15. Article

    Open Access

    Factors influencing long-term outcomes in fibrotic interstitial lung disease (F-ILD) diagnosed through multidisciplinary discussion (MDD): a prospective cohort study

    The diagnostic process for fibrotic interstitial lung disease (F-ILD) is notably intricate, necessitating a multidisciplinary discussion to achieve consensus based on both clinical and radiological features. T...

    Yu-Wan Liao, Ming-Cheng Liu, Yu-Cheng Wu in European Journal of Medical Research (2024)

  16. Article

    Open Access

    Multidisciplinary-derived clinical score for accurate prediction of long-term mortality in fibrotic lung disease patients

    Idiopathic pulmonary fibrosis (IPF) stands out as one of the most aggressive forms of interstitial lung diseases (ILDs), currently without a definitive cure. Multidisciplinary discussion (MDD) is now considere...

    Yu-Wan Liao, Yi-Ming Chen, Ming-Cheng Liu in European Journal of Medical Research (2024)

  17. No Access

    Article

    Feasibility of non-operative management for patients sustained blunt splenic traumas with concomitant aortic injuries

    This study aimed to elucidate the treatment approach for blunt splenic injuries concurrently involving the aorta. We hypothesized that non-operative management failure rates would be higher in such cases, nece...

    Jen-Fu Huang, Chia-Cheng Wang, Shu-Yueh Shen in European Journal of Trauma and Emergency S… (2023)

  18. Article

    Open Access

    A gross deletion of the PAX3 gene in a large Chinese family with Waardenburg syndrome type I

    Shu-Zhi Yang, Lei Hou, **n Qi, Guo-Jian Wang, Sha-Sha Huang in World Journal of Pediatrics (2023)

  19. No Access

    Article

    Impact of chemotherapy on surgical outcomes in ileostomy reversal: a propensity score matching study from a single centre

    In patients with chemotherapy, there is no consensus on the timing of ileostomy closure. Ileostomy reversal could improve the quality of life and minimise the long-term adverse events of delayed closure. In th...

    H.-H. Cheng, Y.-C. Shao, C.-Y. Lin, T.-W. Chiang in Techniques in Coloproctology (2023)

  20. Article

    Open Access

    Comparison of proximal gastrectomy with double-flap technique and double-tract reconstruction for proximal early gastric cancer: a meta-analysis

    Surgical resection is the main treatment for proximal gastric cancer, but there is no consensus on its reconstruction. We carried out a meta-analysis to evaluate the effects of double-tract reconstruction (DTR...

    Qiao-zhen Huang, Peng-cheng Wang, Yan-xin Chen, Shu Lin, Kai Ye in Updates in Surgery (2023)

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