8,349 Result(s)
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Article
Study on the regulatory mechanism of latent membrane protein 2A on GCNT3 expression in nasopharyngeal carcinoma
O-Glycan synthesis enzyme glucosaminyl (N-acetyl) transferase 3 (GCNT3) is closely related to the occurrence and development of various cancers. However, the regulatory mechanism and function of GCNT3 in nasop...
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Single-atom catalysis for advanced oxidation and reduction systems in water decontamination
Water scarcity is an escalating global crisis, posing a severe threat to populations worldwide. Consequently, exploring various materials to remove emerging contaminants from freshwater sources has garnered si...
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Comparative efficacies of two fungal insecticides in field control of cereal aphids heavily infesting winter wheat
Sustainable control of cereal aphids during late spring and early summer requires alternatives to mitigate increasing resistance to chemical insecticides. Emulsifiable oil-formulated Beauveria bassiana ZJU435 (Bb...
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Atypical phenotypes and novel OCRL variations in southern Chinese patients with Lowe syndrome
Lowe syndrome is characterized by the presence of congenital cataracts, psychomotor retardation, and dysfunctional proximal renal tubules. This study presents a case of an atypical phenotype, investigates the ...
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Open AccessAsymmetric total synthesis of polycyclic xanthenes and discovery of a WalK activator active against MRSA
The development of new antibiotics continues to pose challenges, particularly considering the growing threat of multidrug-resistant Staphylococcus aureus. Structurally diverse natural products provide a promising...
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Open AccessEstablishment of a corneal ulcer prognostic model based on machine learning
Corneal infection is a major public health concern worldwide and the most common cause of unilateral corneal blindness. Toxic effects of different microorganisms, such as bacteria and fungi, worsen keratitis l...
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Soft tissue inflammation around upper third molar cause limited mouth opening: common but overlooked
The aim of this study was to explore inflammation of soft tissue around the upper third molar as a prevalent cause of limited mouth opening, identify the clinical and radiographic features, and summarize the t...
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Open AccessHigh-efficiency dysprosium-ion extraction enabled by a biomimetic nanofluidic channel
Biological ion channels exhibit high selectivity and permeability of ions because of their asymmetrical pore structures and surface chemistries. Here, we demonstrate a biomimetic nanofluidic channel (BNC) with...
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Achieving strength–ductility synergy in novel paramagnetic Fe-based medium-entropy alloys through deep cryogenic deformation
Cryogenic pre-deformation treatment has been widely used to effectively improve the comprehensive mechanical properties of steels and novel metals. However, the dislocation evolution and phase transformation i...
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Open AccessSynthetic macrolides overcoming MLSBK-resistant pathogens
Conventional macrolide-lincosamide-streptogramin B-ketolide (MLSBK) antibiotics are unable to counter the growing challenge of antibiotic resistance that is conferred by the constitutive methylation of rRNA base ...
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Open AccessN6-methyladenosine modification of circMARK2 enhances cytoplasmic export and stabilizes LIN28B, contributing to the progression of Wilms tumor
The potential involvement of circular RNAs (circRNAs) and N6-methyladenosine (m6A) modification in the progression of Wilms tumor (WT) has not been fully elucidated. This study investigates the regulatory mechani...
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Open AccessCPEB2-activated axonal translation of VGLUT2 mRNA promotes glutamatergic transmission and presynaptic plasticity
Local translation at synapses is important for rapidly remodeling the synaptic proteome to sustain long-term plasticity and memory. While the regulatory mechanisms underlying memory-associated local translatio...
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Radiomics analysis of dual-layer spectral-detector CT-derived iodine maps for predicting tumor deposits in colorectal cancer
To investigate the value of radiomics analysis of dual-layer spectral-detector computed tomography (DLSCT)-derived iodine maps for predicting tumor deposits (TDs) preoperatively in patients with colorectal can...
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FXR activation remodels hepatic and intestinal transcriptional landscapes in metabolic dysfunction-associated steatohepatitis
The escalating obesity epidemic and aging population have propelled metabolic dysfunction-associated steatohepatitis (MASH) to the forefront of public health concerns. The activation of FXR shows promise to co...
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Clinical characteristics of membranous nephropathy after allogeneic hematopoietic stem cell transplantation: A real-world multicenter study
Membranous nephropathy (MN) is a rare complication that can occur after allogeneic hematopoietic stem cell transplantation (allo-HSCT). MN patients may develop nephrotic syndrome or even kidney failure, which ...
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Constructing three-dimensional hydrogen-bonding network and porous film from chitosan enables high-performance silicon@carbon anode
Anodes based on silicon@carbon (Si@C) composites are expected to be used in the next generation of commercial lithium-ion batteries due to their high specific capacity and high element abundance. However, part...
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Open AccessMeasurement of e+e− → ωη′ cross sections at \( \sqrt{s} \) = 2.000 to 3.080 GeV
We measured the Born cross sections for the process e+e− → ωη′ at 22 center-of-mass energies from 2.000 to 3.080 GeV with the BESIII detector at the BEPCII collider. We observed a resonant structure with a statis...
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Article
The centrosymmetric to non-centrosymmetric transformation induced by alkaline-earth cations producing infrared nonlinear optical AeMn6Ga6S16 (Ae = Ca, Sr)
Non-centrosymmetric (NCS) structure is an indispensable prerequisite for second-order nonlinear optical (NLO) material. Currently, the mainstream approach for designing new NCS structures still relies on chemi...
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An unenhanced 3D-FLAIR sequence using long repetition time and constant flip angle to image endolymphatic hydrops
To evaluate a three-dimensional fluid-attenuated inversion recovery (3D-FLAIR) sequence using a long repetition time (TR) and constant flip angle (CFA) in differentiating between perilymph and endolymph in a p...
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A small molecule compound targeting hemagglutinin inhibits influenza A virus and exhibits broad-spectrum antiviral activity
Influenza A virus (IAV) is a widespread pathogen that poses a significant threat to human health, causing pandemics with high mortality and pathogenicity. Given the emergence of increasingly drug-resistant str...