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9 Result(s)

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  1. No Access

    Article

    Altruism and social rewards

    Scheggia et al.1 have established a behavioral paradigm to explore preferences for ‘altruistic’ or ‘selfish’ choice behavior in mice. The results suggest that altruistic behavior develops through reinforcement le...

    Hee-Sup Shin in Nature Neuroscience (2022)

  2. No Access

    Article

    Dominance effects of ion transport and ion transport regulator genes on the final weight and backfat thickness of Landrace pigs by dominance deviation analysis

    Although there have been plenty of dominance deviation analysis, few studies have dealt with multiple phenotypes. Because researchers focused on multiple phenotypes (final weight and backfat thickness) of Land...

    Young-Sup Lee, Donghyun Shin, Ki-Duk Song in Genes & Genomics (2018)

  3. No Access

    Article

    Overexpression of sweetpotato expansin cDNA (IbEXP1) increases seed yield in Arabidopsis

    Results of transcriptome analyses suggest that expansin genes play an active role in seed development and yield, but gain- or loss-of-function studies have not yet elucidated the functional role(s) of the exp...

    Jung Myung Bae, Man Sup Kwak, Seol Ah Noh, Mi-Joung Oh… in Transgenic Research (2014)

  4. No Access

    Article

    Bidirectional modulation of fear extinction by mediodorsal thalamic firing in mice

    The mediodorsal thalamus links the medial prefrontal cortex and the amygdala in associative learning process in primates. Using mouse models, this study finds that the dual firing modes of mediodorsal thalamus...

    Sukchan Lee, Touqeer Ahmed, Soojung Lee, Huisu Kim, Sukwoo Choi… in Nature Neuroscience (2012)

  5. No Access

    Article

    Observational fear learning involves affective pain system and Cav1.2 Ca2+ channels in ACC

    Primates can develop a conditioned fear response by witnessing other primates being subjected to adverse stimuli. Jeon et al. report that mice are capable of this form of observational fear conditioning and that ...

    Daejong Jeon, Sangwoo Kim, Mattu Chetana, Daewoong Jo, H Earl Ruley… in Nature Neuroscience (2010)

  6. No Access

    Article

    Translation of clock rhythmicity into neural firing in suprachiasmatic nucleus requires mGluR–PLCβ4 signaling

    Phospholipase C β4 (PLCβ4) is expressed in the suprachiasmatic nucleus (SCN), as well as in tissues in the circadian entrainment pathway, including the retina and the lateral geniculate nucleus in the mouse1,2. U...

    Donghyun Park, Sukchan Lee, Kisun Jun, Yeon-Mi Hong, Do Young Kim… in Nature Neuroscience (2003)

  7. No Access

    Article

    PLC-β1, activated via mGluRs, mediates activity-dependent differentiation in cerebral cortex

    During development of the cerebral cortex, the invasion of thalamic axons and subsequent differentiation of cortical neurons are tightly coordinated. Here we provide evidence that glutamate neurotransmission t...

    Anthony J. Hannan, Colin Blakemore, Alla Katsnelson, Tania Vitalis… in Nature Neuroscience (2001)

  8. No Access

    Article

    Insertion of a retroviral solo long terminal repeat in mdr-3 locus disrupts mRNA splicing in mice

    Previously, the abermectin-induced neurotoxicity of subpopulation of CF-1 mice was shown to be caused by the deficiency of mdr-3 P-glycoprotein. Here, we have characterized the molecular nature of the mdr-3 gene...

    Kisun Jun, Seong-Beom Lee, Hee-Sup Shin in Mammalian Genome (2000)

  9. No Access

    Article

    The murine MHC encodes a mammalian homolog of bacterial ribosomal protein S13

    The mouse major histocompatibility complex (MHC) contains many genes in addition to the classical immune response genes. We have screened overlap** cosmid clones covering 170 kb of the H-2K region for genes exp...

    Armand J. MacMurray, Hee-Sup Shin in Mammalian Genome (1992)