1,356 Result(s)
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**-Rong Huang
English
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Article
Machine Learning Approach in Dosage Individualization of Isoniazid for Tuberculosis
Isoniazid is a first-line antituberculosis agent with high variability, which would profit from individualized dosing. Concentrations of isoniazid at 2 h (C2h), as an indicator of safety and efficacy, are importa...
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Article
ErbB4 deficiency exacerbates olfactory dysfunction in an early-stage Alzheimer’s disease mouse model
Olfactory dysfunction is increasingly recognized as an early indicator of Alzheimer’s disease (AD). Aberrations in GABAergic function and the excitatory/inhibitory (E/I) balance within the olfactory bulb (OB) ...
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Article
Open AccessEngineered droplet-forming peptide as photocontrollable phase modulator for fused in sarcoma protein
The assembly and disassembly of biomolecular condensates are crucial for the subcellular compartmentalization of biomolecules in the control of cellular reactions. Recently, a correlation has been discovered b...
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Open AccessEffects of edge disorder on the stability of quantum oscillations in two-dimensional coupled systems
This paper utilizes the theory of quantum diffusion to analyze the electron probability and spreading width of a wavepacket on each layer in a two-dimensional (2D) coupled system with edge disorder, aiming to ...
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Article
Beyond black-box models: explainable AI for embryo ploidy prediction and patient-centric consultation
To determine if an explainable artificial intelligence (XAI) model enhances the accuracy and transparency of predicting embryo ploidy status based on embryonic characteristics and clinical data.
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Article
Coastal citizen science monitoring and suggested conservation strategy: ghost crab survey at Suao Dakenggu, Taiwan
Beaches provide a buffer zone between the sea and the land, which mitigates the impact of natural hazards on waterfront residents. In this study, the beach at the Dakenggu community in Suao Township, Yilan, wa...
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Article
Salvage haploidentical transplantation for graft failure after first haploidentical allogeneic stem cell transplantation: an updated experience
Graft failure is a fatal complication following allogeneic stem cell transplantation where a second transplantation is usually required for salvage. However, there are no recommended regimens for second transp...
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Open AccessNeferine inhibits BMECs pyroptosis and maintains blood–brain barrier integrity in ischemic stroke by triggering a cascade reaction of PGC-1α
Blood–brain barrier disruption is a critical pathological event in the progression of ischemic stroke (IS). Most studies regarding the therapeutic potential of neferine (Nef) on IS have focused on neuroprotect...
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Article
Open AccessPJA1-mediated suppression of pyroptosis as a driver of docetaxel resistance in nasopharyngeal carcinoma
Chemoresistance is a main reason for treatment failure in patients with nasopharyngeal carcinoma, but the exact regulatory mechanism underlying chemoresistance in nasopharyngeal carcinoma remains to be elucida...
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Article
Resolvin D1 delivery to lesional macrophages using antioxidative black phosphorus nanosheets for atherosclerosis treatment
The buildup of plaques in atherosclerosis leads to cardiovascular events, with chronic unresolved inflammation and overproduction of reactive oxygen species (ROS) being major drivers of plaque progression. Nan...
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Article
Open AccessLandform and lithospheric development contribute to the assembly of mountain floras in China
Although it is well documented that mountains tend to exhibit high biodiversity, how geological processes affect the assemblage of montane floras is a matter of ongoing research. Here, we explore landform-spec...
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Open AccessSpatial accessibility and inequality analysis of rabies-exposed patients to rabies post-exposure prophylaxis clinics in Guangzhou City, China
The incidence of rabies exposure is high and increasing in China, leading to an urgent demand of rabies post-exposure prophylaxis (PEP) clinics for the injured. However, the spatial accessibility and inequalit...
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Article
Application of ambient noise tomography to coastal granite islands: A case study of Wuzhizhou Island in Hainan, China
Islands are valuable land resources in the ocean, and their detailed subsurface seismic velocity structures are highly important for underground space utilization, engineering construction, and geological disa...
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Open AccessCantonese natural language processing in the transformers era: a survey and current challenges
Despite being spoken by a large population of speakers worldwide, Cantonese is under-resourced in terms of the data scale and diversity compared to other major languages. This limitation has excluded it from t...
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Article
Effects of Humic Acid-Copper Interactions on Growth, Nutrient Absorption, and Photosynthetic Performance of Citrus sinensis Seedlings in Sand Culture
In China, high copper (Cu) and low organic matter often occur in some citrus orchard soils. However, the underlying mechanisms by which humic acid (HA) stimulates growth and mitigates Cu toxicity of citrus see...
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Article
Identification of a longevity gene through evolutionary rate covariation of insect mito-nuclear genomes
Oxidative phosphorylation, essential for energy metabolism and linked to the regulation of longevity, involves mitochondrial and nuclear genes. The functions of these genes and their evolutionary rate covariat...
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Open AccessA multicenter prospective study on the management of hepatoblastoma in children: a report from the Chinese Children’s Cancer Group
This study aimed to identify survival risk factors in Chinese children with hepatoblastoma (HB) and assess the effectiveness of the new treatment protocol proposed by the Chinese Children’s Cancer Group (CCCG)...
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Article
Edge Electronic States and Direct Bandgap in Si Nanostructures on Silicon Oxide
The nanostructures on silicon oxide, as a new phase of matter, only allows conducting electrons to exist on its surfaces, in which the edge electronic states dramatically provide intriguing insights into the w...
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Article
W-band Dual-band Filter and Diplexer Based on Mixed TE301- and TE102-Mode Cavities
In this article, waveguide dual-band filter and diplexer working on W-band are synthesized through cascading mixed TE301- and TE102-mode cavities as well as TE101-mode resonators. Based on the discussion of top r...
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Article
Upregulation of eIF2α by m6A modification accelerates the proliferation of pulmonary artery smooth muscle cells in MCT-induced pulmonary arterial hypertension rats
Pulmonary arterial hypertension (PAH) is a malignant cardiovascular disease. Eukaryotic initiation factor 2α (eIF2α) plays an important role in the proliferation of pulmonary artery smooth muscle cells (PASMCs...
