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  1. Article

    Open Access

    Combined detection of serum EFNA1 and MMP13 as diagnostic biomarker for gastric cancer

    We previously identified that serum EFNA1 and MMP13 were potential biomarker for early detection of esophageal squamous cell carcinoma. In this study, our aim is to explore the diagnostic value of serum EFNA1 ...

    Ling-Yu Chu, Fang-Cai Wu, Hai-Peng Guo, Jian-Jun **e, Qi-Qi Qu in Scientific Reports (2024)

  2. Article

    Open Access

    R2-ISS staging combined with circulating plasma cells improves risk stratification for newly diagnosed multiple myeloma: a single-center real-world study

    We aimed to evaluate if circulating plasma cells (CPC) detected by flow cytometry could add prognostic value of R2-ISS staging. We collected the electronic medical records of 336 newly diagnosed MM patients (N...

    Bin Chu, Yu-tong Wang, Shan Gao, Lei Shi, Min-qiu Lu, Li-juan Fang in Annals of Hematology (2024)

  3. No Access

    Article

    Estimating the Mechanical Properties of Rocks and Rock Masses Based on Mineral Micromechanics Testing

  4. Estimation of rock uniaxial compressive strength and elastic modulus from mineral micromehanical properties.

  5. Upscaling tech...

  6. **u-yang Liu, Ding-** Xu, Shao-jun Li in Rock Mechanics and Rock Engineering (2024)

  7. Article

    Open Access

    Railway track settlement patterns and control measures for multi-tunnel construction underneath a station track group: a case study

    This paper is based on the proximity engineering project of the Baishiyi tunnel group passing under the Chongqing West Station track group. Considering the train load and the spatial relationship of the tunnel...

    Pinpin Li, Feng Lu, Haiyun Huang, Wenge Qiu in Scientific Reports (2024)

  8. Article

    Open Access

    Cold exposure-induced plasma exosomes impair bone mass by inhibiting autophagy

    Recently, environmental temperature has been shown to regulate bone homeostasis. However, the mechanisms by which cold exposure affects bone mass remain unclear. In our present study, we observed that exposure...

    Li-Min Lei, Fu-**ng-Zi Li, **ao Lin, Feng Xu, Su-Kang Shan in Journal of Nanobiotechnology (2024)

  9. Article

    Open Access

    Augmented microglial endoplasmic reticulum-mitochondria contacts mediate depression-like behavior in mice induced by chronic social defeat stress

    Extracellular ATP (eATP) signaling through the P2X7 receptor pathway is widely believed to trigger NLRP3 inflammasome assembly in microglia, potentially contributing to depression. However, the cellular stress...

    Jia-Rui Zhang, Shi-Yu Shen, Meng-Ying Zhai, Zu-Qi Shen, Wei Li in Nature Communications (2024)

  10. No Access

    Article

    The First Report of Tritrichomonas Foetus and Tetratrichomonas Buttreyi in Raccoon Dogs (Nyctereutes Procyonoides) in China

    In recent years, the trichomonosis in raccoon dogs in China had occurred frequently. Pentatrichomonas hominis had been described in raccoon dogs in China in some previous studies.

    Dong-qian Chen, Qiu-yue Wang, Qiao-qiao Li, **n-yu Luo, **ng-hua Wu in Acta Parasitologica (2024)

  11. Article

    Open Access

    Landform and lithospheric development contribute to the assembly of mountain floras in China

    Although it is well documented that mountains tend to exhibit high biodiversity, how geological processes affect the assemblage of montane floras is a matter of ongoing research. Here, we explore landform-spec...

    Wan-Yi Zhao, Zhong-Cheng Liu, Shi Shi, Jie-Lan Li, Ke-Wang Xu in Nature Communications (2024)

  12. No Access

    Article

    Hermite Expansion Technique for Model Reduction of Circuit Systems with Delay Components

    Model order reduction technique provides an effective way to reduce computational complexity in large-scale circuit simulations. This paper proposes a new model order reduction method for delay circuit systems...

    Zhi-Yong Qiu, Zhen-Hua Guo, Yao-Lin Jiang in Circuits, Systems, and Signal Processing (2024)

  13. Article

    Open Access

    AKI-Pro score for predicting progression to severe acute kidney injury or death in patients with early acute kidney injury after cardiac surgery

    No reliable clinical tools exist to predict acute kidney injury (AKI) progression. We aim to explore a scoring system for predicting the composite outcome of progression to severe AKI or death within seven day...

    Ying Su, Peng Wang, Yan Hu, Wen-jun Liu, Yi-jie Zhang in Journal of Translational Medicine (2024)

  14. Article

    Open Access

    Distinct characteristics of the gut virome in patients with osteoarthritis and gouty arthritis

    The gut microbiota and its metabolites play crucial roles in pathogenesis of arthritis, highlighting gut microbiota as a promising avenue for modulating autoimmunity. However, the characterization of the gut v...

    Chang-Ming Chen, Qiu-Long Yan, Ruo-Chun Guo, Fang Tang in Journal of Translational Medicine (2024)

  15. No Access

    Article

    Characteristics of tandem repeat inheritance and sympathetic nerve involvement in GAA-FGF14 ataxia

    Intronic GAA repeat expansion ([GAA] ≥250) in FGF14 is associated with the late-onset neurodegenerative disorder, spinocerebellar ataxia 27B (SCA27B, GAA-FGF14 ataxia). We aim to determine the prevalence of the G...

    Ze-Hong Zheng, Chun-Yan Cao, Bi Cheng, Ru-Ying Yuan in Journal of Human Genetics (2024)

  16. Article

    Open Access

    The effect of modified Qiyuan paste on mice with low immunity and sleep deprivation by regulating GABA nerve and immune system

    Low immunity and sleep disorders are prevalent suboptimal health conditions in contemporary populations, which render them susceptible to the infiltration of pathogenic factors. LJC, which has a long history i...

    Mei Rong, Jiu-Jie Jia, Min-Qiu Lin, **ng-Li-Shang He, Zhi-Yi **e in Chinese Medicine (2024)

  17. Article

    Open Access

    De novo design of a nanoregulator for the dynamic restoration of ovarian tissue in cryopreservation and transplantation

    The cryopreservation and transplantation of ovarian tissue underscore its paramount importance in safeguarding reproductive capacity and ameliorating reproductive disorders. However, challenges persist in ovar...

    Min Jiang, Guo-Hui Zhang, Yuan Yu, Yu-Hong Zhao, Jun Liu in Journal of Nanobiotechnology (2024)

  18. Article

    Open Access

    Clinical outcomes and biomarker exploration of first-line PD-1 inhibitors plus chemotherapy in patients with low PD-L1-expressing of gastric or gastroesophageal junction adenocarcinoma

    The beneficial effects of first-line programmed death-1 (PD-1) inhibitors plus chemotherapy in patients with low programmed death-ligand 1 (PD-L1)-expressing advanced gastric or gastroesophageal junction (G/GE...

    Yu-Ting Sun, Shi-Xun Lu, Ming-Yu Lai, **a Yang in Cancer Immunology, Immunotherapy (2024)

  19. No Access

    Article

    Mitogen-Activated Protein Kinases Mediate Adventitial Fibroblast Activation and Neointima Formation via GATA4/Cyclin D1 Axis

    Activation of mitogen-activated protein kinases (MAPKs) by pathological stimuli participates in cardiovascular diseases. Dysfunction of adventitial fibroblast has emerged as a critical regulator in vascular re...

    **g Chen, **-Qiu Wei, Mo-Na Hong, Zhong Zhang in Cardiovascular Drugs and Therapy (2024)

  20. No Access

    Article

    Hydrogen production from hydrolysis of NaBH4 solution over Co–Fe–B@g-C3N4/NF thin film catalyst

    In this study, the double loaded Co–Fe–B@g-C3N4/NF (NF: Ni foam) thin film catalysts were prepared for the first time via chemical deposition method at room temperature. By optimizing the reducing agent concentra...

    Yan Wang, Jia-**n Ma, Jian Ren, Di Zhang, Feng-Yan Xu, Ke Zhang in Rare Metals (2024)

  21. No Access

    Article

    Development and Validation of a Prognostic Model for Postoperative Anastomotic Recurrence in Siewert II or III Adenocarcinomas Without Neoadjuvant Therapy in an East Asian Population

    Anastomotic recurrence leads to poor prognosis in patients with Siewert II or III adenocarcinoma who undergo radical gastrectomy and do not receive neoadjuvant therapy. We aimed to establish a prognostic model...

    Ming-bin Huang, Chao Xu, Hong Chen, Jian-xian Lin in Journal of Gastrointestinal Cancer (2024)

  22. Article

    Open Access

    Association between pretreatment emotional distress and immune checkpoint inhibitor response in non-small-cell lung cancer

    Emotional distress (ED), commonly characterized by symptoms of depression and/or anxiety, is prevalent in patients with cancer. Preclinical studies suggest that ED can impair antitumor immune responses, but fe...

    Yue Zeng, Chun-Hong Hu, Yi-Zheng Li, Jian-Song Zhou, Shu-**ng Wang in Nature Medicine (2024)

  23. Article

    Open Access

    Van der Waals polarity-engineered 3D integration of 2D complementary logic

    Vertical three-dimensional integration of two-dimensional (2D) semiconductors holds great promise, as it offers the possibility to scale up logic layers in the z axis13. Indeed, vertical complementary field-effe...

    Yimeng Guo, Jiangxu Li, Xuepeng Zhan, Chunwen Wang, Min Li, Biao Zhang in Nature (2024)

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