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Rab11b promotes M1-like macrophage polarization by restraining autophagic degradation of NLRP3 in alcohol-associated liver disease

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  1. Article

    Open Access

    PEX3 promotes regenerative repair after myocardial injury in mice through facilitating plasma membrane localization of ITGB3

    The peroxisome is a versatile organelle that performs diverse metabolic functions. PEX3, a critical regulator of the peroxisome, participates in various biological processes associated with the peroxisome. Whe...

    Jia-Teng Sun, Zi-Mu Wang, Liu-Hua Zhou, Tong-Tong Yang, Di Zhao in Communications Biology (2024)

  2. Article

    Open Access

    Develo** an entrustable professional activity for providing health education and consultation in occupational therapy and examining its validity

    Entrustable Professional Activities (EPA)-based assessment is easily and intuitively used in evaluating the learning outcomes of competency-based medical education (CBME). This study aimed to develop an EPA fo...

    Chung-Pei Fu, Ching-Kai Huang, Yi-Chiun Yang, Wei-Sheng Liao in BMC Medical Education (2024)

  3. Article

    Open Access

    Novel radiopaque ethanol injection: physicochemical properties, animal experiments, and clinical application in vascular malformations

    Despite the efficacy of absolute ethanol (EtOH), its radiolucency introduces several risks in interventional therapy for treating vascular malformations. This study aims to develop a novel radiopaque ethanol i...

    Yu-Chen Shen, De-Ming Wang, **-Tao Yang, Zhen-Feng Wang in Military Medical Research (2024)

  4. Article

    Open Access

    Using a DNA mini-barcode within the ITS region to identify toxic Amanita in mushroom poisoning cases

    Mushroom poisoning contributes significantly to global foodborne diseases and related fatalities. Amanita mushrooms frequently cause such poisonings; however, identifying these toxic species is challenging due to...

    Ran-Ran **ng, Wen-Ming Bai, Di Hu, Ting-Ting Deng in Applied Microbiology and Biotechnology (2024)

  5. Article

    Open Access

    Clinical significance and prospective mechanism of increased CDKN2A expression in small cell lung cancer

    Although it has been shown that cyclin dependent kinase inhibitor 2A (CDKN2A) plays a significant role in a number of malignancies, its clinicopathological value and function in small cell lung cancer (SCLC) i...

    Dong-Ming Li, Guo-Sheng Li, Jian-Di Li, Feng Chen in Clinical and Translational Oncology (2024)

  6. Article

    Open Access

    Two-dimensional materials for future information technology: status and prospects

    Over the past 70 years, the semiconductor industry has undergone transformative changes, largely driven by the miniaturization of devices and the integration of innovative structures and materials. Two-dimensi...

    Hao Qiu, Zhihao Yu, Tiange Zhao, Qi Zhang in Science China Information Sciences (2024)

  7. Article

    Open Access

    Sustainable upcycling of mixed spent cathodes to a high-voltage polyanionic cathode material

    Sustainable battery recycling is essential for achieving resource conservation and alleviating environmental issues. Many open/closed-loop strategies for critical metal recycling or direct recovery aim at a si...

    Guanjun Ji, Di Tang, Junxiong Wang, Zheng Liang, Haocheng Ji in Nature Communications (2024)

  8. Article

    Open Access

    Rotational magnetoelectric switching in orthorhombic multiferroics

    Controlling the direction of ferromagnetism and antiferromagnetism by an electric field in single-phase multiferroics will open the door to the next generation of devices for spintronics and electronics. The t...

    Xu Li, Hao Tian, Lan Chen, Hongjun **ang, Jun-Ming Liu in npj Computational Materials (2024)

  9. Article

    Retraction Note: Sonochemical Synthesis of Two New Nanostructured La(III) Coordination Polymers: Inducing Tongue Cancer Cell Apoptosis and ROS Accumulation by Targeting FHIT

    Jian-Ming Tang, Wan-Ting Fan, Po-Yi Chu, Dong-Lei Wu in Journal of Cluster Science (2024)

  10. Article

    Open Access

    Virome diversity shaped by genetic evolution and ecological landscape of Haemaphysalis longicornis

    Haemaphysalis longicornis is drawing attentions for its geographic invasion, extending population, and emerging disease threat. However, there are still substantial gaps in our knowledge of viral composition in r...

    Run-Ze Ye, Yu-Yu Li, Da-Li Xu, Bai-Hui Wang, **ao-Yang Wang, Ming-Zhu Zhang in Microbiome (2024)

  11. Article

    Open Access

    Pro-ferroptotic signaling promotes arterial aging via vascular smooth muscle cell senescence

    Senescence of vascular smooth muscle cells (VSMCs) contributes to aging-related cardiovascular diseases by promoting arterial remodelling and stiffness. Ferroptosis is a novel type of regulated cell death asso...

    Di-Yang Sun, Wen-Bin Wu, Jian-** Wu, Yu Shi, Jia-Jun Xu in Nature Communications (2024)

  12. Article

    Open Access

    Gut microbiota-derived LCA mediates the protective effect of PEDV infection in piglets

    The gut microbiota is a critical factor in the regulation of host health, but the relationship between the differential resistance of hosts to pathogens and the interaction of gut microbes is not yet clear. He...

    Jun-Hong **ng, Tian-Ming Niu, Bo-Shi Zou, Gui-Lian Yang, Chun-Wei Shi in Microbiome (2024)

  13. Article

    Open Access

    Exploring the use of graphene lubricant and TiO2 nanolubricants in micro deep drawing of stainless steel SUS301

    This study investigates the effects of different lubrication conditions on drawing force and microcup formation during micro deep drawing (MDD). Results show that graphene lubricant, in combination with TiO2 nano...

    Di Pan, Guangqing Zhang, Fanghui Jia, Hui Wu in The International Journal of Advanced Manu… (2024)

  14. Article

    Open Access

    Macro CD5L+ deteriorates CD8+T cells exhaustion and impairs combination of Gemcitabine-Oxaliplatin-Lenvatinib-anti-PD1 therapy in intrahepatic cholangiocarcinoma

    Intratumoral immune status influences tumor therapeutic response, but it remains largely unclear how the status determines therapies for patients with intrahepatic cholangiocarcinoma. Here, we examine the sing...

    Jia-Cheng Lu, Lei-Lei Wu, Yi-Ning Sun, **ao-Yong Huang, Chao Gao in Nature Communications (2024)

  15. Article

    Open Access

    Red blood cell distribution width is associated with sarcopenia risk in early-stage non-small cell lung cancer

    Sarcopenia has received increasing attention in non-small cell lung cancer (NSCLC). Red blood cell distribution width (RDW) is a significant component of the complete blood count and indicates the heterogeneit...

    Qing-chun Jia, Ling Qin, Ye Niu, Le Liu, **-** Liu, Shi-di Miao in BMC Cancer (2024)

  16. Article

    Open Access

    Age-related decline in melatonin contributes to enhanced osteoclastogenesis via disruption of redox homeostasis

    Increased oxidative stress contributes to enhanced osteoclastogenesis and age-related bone loss. Melatonin (MT) is an endogenous antioxidant and declines with aging. However, it was unclear whether the decline...

    Di-Zheng Wu, Guo-Zheng Zhu, Kai Zhao, Jia-Wen Gao, Gui-**ng Cai in Molecular Medicine (2024)

  17. Article

    Open Access

    Tunable and parabolic piezoelectricity in hafnia under epitaxial strain

    Piezoelectrics are a class of functional materials that have been extensively used for application in modern electro-mechanical and mechatronics technologies. The sign of longitudinal piezoelectric coefficient...

    Hao Cheng, Peijie Jiao, Jian Wang, Mingkai Qing, Yu Deng in Nature Communications (2024)

  18. Article

    Open Access

    Elevated FBXL6 activates both wild-type KRAS and mutant KRASG12D and drives HCC tumorigenesis via the ERK/mTOR/PRELID2/ROS axis in mice

    Kirsten rat sarcoma (KRAS) and mutant KRASG12D have been implicated in human cancers, but it remains unclear whether their activation requires ubiquitination. This study aimed to investigate whether and how F-box...

    Hao-Jun **ong, Hong-Qiang Yu, Jie Zhang, Lei Fang, Di Wu in Military Medical Research (2023)

  19. Article

    Open Access

    Comprehensive genomic profiling of breast cancers characterizes germline-somatic mutation interactions mediating therapeutic vulnerabilities

    Germline-somatic mutation interactions are universal and associated with tumorigenesis, but their role in breast cancer, especially in non-Caucasians, remains poorly characterized. We performed large-scale pro...

    Chao Chen, Cai-** Lin, Yu-Chen Pei, Ding Ma, Li Liao, Si-Yuan Li in Cell Discovery (2023)

  20. Article

    Open Access

    COVID-19 and influenza infections mediate distinct pulmonary cellular and transcriptomic changes

    SARS-CoV-2 infection can cause persistent respiratory sequelae. However, the underlying mechanisms remain unclear. Here we report that sub-lethally infected K18-human ACE2 mice show patchy pneumonia associated wi...

    Chenxiao Wang, Mst Shamima Khatun, Zhe Zhang, Michaela J. Allen in Communications Biology (2023)

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