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  1. Article

    Open Access

    A separate-dural-incision method of extradural dumbbell spinal schwannoma resection: cumulative experience at a single center

    To present our experience in the surgical management of completely extradural dumbbell spinal schwannomas with a new surgical strategy.

    Li Jia, Minghui Zeng, Zhiyu **, Lin Wang, Jiang Liu in BMC Surgery (2024)

  2. Article

    Open Access

    LASSO-derived nomogram for early identification of pediatric monogenic lupus

    Monogenic lupus is defined as systemic lupus erythematosus (SLE)/SLE-like patients with either dominantly or recessively inherited pathogenic variants in a single gene with high penetrance. However, because th...

    Tian-Yu Zhang, Wei Wang, Si-Hao Gao, Zhong-Xun Yu, Wei Wang in World Journal of Pediatrics (2024)

  3. Article

    Open Access

    Exome sequencing and genome-wide association analyses unveils the genetic predisposition in hydroxychloroquine retinopathy

    To unveil the candidate susceptibility genes in chloroquine/hydroxychloroquine (CQ/HCQ) retinopathy using whole exome sequencing (WES) and genome-wide association study (GWAS).

    Hsun-I Chiu, Hui-Chen Cheng, Chih-Chiau Wu, Shih-Jen Chen, De-Kuang Hwang in Eye (2024)

  4. No Access

    Article

    CYTOR-NFAT1 feedback loop regulates epithelial-mesenchymal transition of retinal pigment epithelial cells

    Epithelial mesenchymal transition (EMT) occurring in retinal pigment epithelial cells (RPE) is a crucial mechanism that contributes to the development of age-related macular degeneration (AMD), a pivotal facto...

    Rong Zhang, Lin Wang, Yang Li, Yan Liu, Kui Dong, Ya**g Pei, Junmei Zhao in Human Cell (2024)

  5. No Access

    Article

    Early Contrast-Enhanced MR for Diagnosing Complete Tumor Response of Locally Advanced Esophageal Squamous Cell Carcinoma After Neoadjuvant Therapy: A Retrospective Comparative Study

    This study assessed the performance of early contrast-enhanced magnetic resonance (ECE-MR) in the detecting of complete tumor response (ypT0) in patients with esophageal squamous cell carcinoma following neoad...

    Yan-Jie Shi MD, Shuo Yan MD, **n Yang MD, Zhen Guan MD in Annals of Surgical Oncology (2024)

  6. Article

    Open Access

    Therapeutic potential of extracellular vesicles from diverse sources in cancer treatment

    Cancer, a prevalent and complex disease, presents a significant challenge to the medical community. It is characterized by irregular cell differentiation, excessive proliferation, uncontrolled growth, invasion...

    Haihong Lin, Jun Zhou, Tao Ding, Yifan Zhu in European Journal of Medical Research (2024)

  7. Article

    Open Access

    Balloon cells in malformations of cortical development: friends or foes?

    Balloon cells (BCs) are specific pathological marker of cortical malformations during brain development, often associated with epilepsy and development delay. Although a large number of studies have investigat...

    Zili Liu, Xuefeng Shen, Kaomin Lin, Fengpeng Wang, ** Gao, Yi Yao in Acta Epileptologica (2024)

  8. Article

    Expert consensus on the diagnosis and treatment of end-stage liver disease complicated by infections

    End-stage liver disease (ESLD) is a life-threatening clinical syndrome and when complicated with infection the mortality is markedly increased. In patients with ESLD, bacterial or fungal infection can induce o...

    Tao Chen, Guang Chen, Guiqiang Wang, Sombat Treeprasertsuk in Hepatology International (2024)

  9. No Access

    Article

    Sirolimus can promote the disappearance of renal angiomyolipoma associated with tuberous sclerosis complex: a prospective cohort study

    Renal angiomyolipoma (RAML) is the most common kidney lesion in patients with tuberous sclerosis complex (TSC), affecting about 80% of patients. It is a benign tumor that grows over time, usually bilaterally, ...

    Shuo Dun, Yang-Yang Wang, Lin Wan, Qiu-Hong Wang, Qian Lu in World Journal of Pediatrics (2024)

  10. No Access

    Article

    Patients undergoing liver resection for non-alcoholic fatty liver disease-related hepatocellular carcinoma and those for viral hepatitis-related hepatocellular carcinoma have similar survival outcomes

    Numerous studies have compared outcomes of liver resection (LR) of patients with non-alcoholic fatty liver disease (NAFLD)-related hepatocellular carcinoma (HCC) to those of patients with non-NAFLD-related HCC...

    Yi-Hao Yen, Fang-Ying Kuo, Hock-Liew Eng, Yueh-Wei Liu in Updates in Surgery (2024)

  11. Article

    Open Access

    Enabling the design of surgical instruments for under-resourced patients through metal additive manufacturing: ulnar shortening osteotomy as an example

    Ulnar shortening osteotomy (USO) has demonstrated good outcomes for patients with ulnar impaction syndrome. To minimize complications such as non-union, precise osteotomy and firm fixation are warranted. Despi...

    Kuan-Lin Chen, Cheng-Yu Yin, Hui-Kuang Huang, Yi-Chao Huang in 3D Printing in Medicine (2024)

  12. Article

    Open Access

    Development and validation of a nomogram to predict postoperative delirium in older patients after major abdominal surgery: a retrospective case-control study

    Postoperative delirium is a common complication in older patients, with poor long-term outcomes. This study aimed to investigate risk factors and develop a predictive model for postoperative delirium in older ...

    Yun-Gen Luo, **ao-Dong Wu, Yu-**ang Song, **ao-Lin Wang, Kai Liu in Perioperative Medicine (2024)

  13. Article

    Open Access

    Correlating Reiff scores with clinical, functional, and prognostic factors: characterizing noncystic fibrosis bronchiectasis severity: validation from a nationwide multicenter study in Taiwan

    Our study aimed to confirm a simplified radiological scoring system, derived from a modified Reiff score, to evaluate its relationship with clinical symptoms and predictive outcomes in Taiwanese patients with ...

    Wen-Chien Cheng, Chia-Ling Chang, Chau-Chyun Sheu in European Journal of Medical Research (2024)

  14. Article

    Open Access

    Abnormal coagulation after hepatectomy in patients with normal preoperative coagulation function

    To explore the risk factors for postoperative abnormal coagulation (PAC) and establish a predictive model for patients with normal preoperative coagulation function who underwent hepatectomy.

    Liting Kuang, Weibin Lin, Dahui Wang, Bin Chen in BMC Surgery (2024)

  15. Article

    Open Access

    Risk factors for renal outcomes in children with antineutrophil cytoplasmic antibody-associated vasculitis: a nationwide retrospective study in China

    Pediatric antineutrophil cytoplasmic antibody-associated vasculitis (AAV) is a life-threatening systemic vasculitis featured by liability to renal involvement. However, there are few studies on the risk factor...

    Li-Wen Tan, Jun-Li Wan, Chun-Hua Zhu, Hong Xu, Zheng-Kun **a in World Journal of Pediatrics (2024)

  16. No Access

    Article

    Effect of Sarcopenic Obesity on Weight Loss Outcomes and Quality of Life after Laparoscopic Sleeve Gastrectomy: A Retrospective Cohort Study

    Sarcopenic obesity may affect the health outcome of people with obesity after laparoscopic sleeve gastrectomy (LSG). To assess the impact of sarcopenic obesity (SO) on weight loss outcomes and improvement of q...

    Zhi-**n Shang-Guan, Guang-Tan Lin, Zhi-Yu Liu, Qing Zhong, Qiang Huang in Obesity Surgery (2024)

  17. No Access

    Article

    Robot-assisted versus laparoscopic-assisted gastrectomy among malnourished patients with gastric cancer based on textbook outcome

    Textbook outcome (TO) has been widely employed as a comprehensive indicator to assess the short-term prognosis of patients with cancer. Preoperative malnutrition is a potential risk factor for adverse surgical...

    Guang-Tan Lin, Jun-Yu Chen, Zhi-**n Shang-Guan, Deng-Hui Fan in Surgical Endoscopy (2024)

  18. No Access

    Article

    Correlation of contrast sensitivity with ganglion cell/inner plexiform layer thickness and damage location in glaucoma with varying severity

    To investigate the correlation of contrast sensitivity with macular region ganglion cell/inner plexiform layer (GC/IPL) thickness and damage location in open-angle glaucoma (OAG) of varying severity.

    Ruiqi Pang, Jieting Peng, Qing Zhang, Kai Cao, Zhong-Lin Lu, Ningli Wang in Eye (2024)

  19. No Access

    Article

    Outcomes of Salvage Surgery Versus Non-Salvage Surgery for Initially Unresectable Hepatocellular Carcinoma After Conversion Therapy with Transcatheter Arterial Chemoembolization Combined with Lenvatinib Plus Anti-PD-1 Antibody: A Multicenter Retrospective Study

    Combination treatment with transcatheter arterial chemoembolization (TACE), lenvatinib, and anti-programmed death-1 (anti-PD-1) antibodies (triple therapy) has a high rate of tumor response and converted resec...

    Jun-Yi Wu MD, PhD, Jia-Yi Wu MD, Yang-Kai Fu MD in Annals of Surgical Oncology (2024)

  20. Article

    Open Access

    Overexpressed KCNK1 regulates potassium channels affecting molecular mechanisms and biological pathways in bladder cancer

    This study aimed to explore the expression, molecular mechanism and its biological function of potassium two pore domain channel subfamily K member 1 (KCNK1) in bladder cancer (BC).

    Wei Zhang, **ao-Song Chen, Ying Wei, **ao-Min Wang in European Journal of Medical Research (2024)

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