3,007 Result(s)
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Open AccessEnhanced electrocatalytic biomass oxidation at low voltage by Ni2+-O-Pd interfaces
Challenges in direct catalytic oxidation of biomass-derived aldehyde and alcohol into acid with high activity and selectivity hinder the widespread biomass application. Herein, we demonstrate that a Pd/Ni(OH)2 ca...
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Open AccessIdentification of candidate single-nucleotide polymorphisms (SNPs) and genes associated with sugarcane leaf scald disease
Leaf scald, caused by Xanthomonas albilineans, is a severe disease affecting sugarcane worldwide. One of the most practical ways to control it is by develo** resistant sugarcane cultivars. It is essential to id...
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Open AccessSilicon photocathode functionalized with osmium complex catalyst for selective catalytic conversion of CO2 to methane
Solar-driven CO2 reduction to yield high-value chemicals presents an appealing avenue for combating climate change, yet achieving selective production of specific products remains a significant challenge. We show...
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Open AccessCholine consumption reduces CVD risk via body composition modification
Despite extensive research on the relationship between choline and cardiovascular disease (CVD), conflicting findings have been reported. We aim to investigate the relationship between choline and CVD. Our ana...
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Open AccessInhibition of DUSP18 impairs cholesterol biosynthesis and promotes anti-tumor immunity in colorectal cancer
Tumor cells reprogram their metabolism to produce specialized metabolites that both fuel their own growth and license tumor immune evasion. However, the relationships between these functions remain poorly unde...
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Open AccessPrecision arbovirus serology with a pan-arbovirus peptidome
Arthropod-borne viruses represent a crucial public health threat. Current arboviral serology assays are either labor intensive or incapable of distinguishing closely related viruses, and many zoonotic arboviru...
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Open AccessWavelength-tunable high-fidelity entangled photon sources enabled by dual Stark effects
The construction of a large-scale quantum internet requires quantum repeaters containing multiple entangled photon sources with identical wavelengths. Semiconductor quantum dots can generate entangled photon p...
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Open AccessHistamine H1 receptors in dentate gyrus-projecting cholinergic neurons of the medial septum suppress contextual fear retrieval in mice
Fear memory is essential for survival and adaptation, yet excessive fear memories can lead to emotional disabilities and mental disorders. Despite previous researches have indicated that histamine H1 receptor (H1
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Open AccessStimuli-responsive mechanically interlocked polymer wrinkles
Artificial wrinkles, especially those with responsive erasure/regeneration behaviors have gained extensive interest due to their potential in smart applications. However, current wrinkle modulation methods pri...
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Open AccessPartitioning and aggregating cross-tissue and tissue-specific genetic effects to identify gene-trait associations
TWAS have shown great promise in extending GWAS loci to a functional understanding of disease mechanisms. In an effort to fully unleash the TWAS and GWAS information, we propose MTWAS, a statistical framework ...
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Open AccessTargeting the transmembrane cytokine co-receptor neuropilin-1 in distal tubules improves renal injury and fibrosis
Neuropilin-1 (NRP1), a co-receptor for various cytokines, including TGF-β, has been identified as a potential therapeutic target for fibrosis. However, its role and mechanism in renal fibrosis remains elusive....
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Open AccessRefining silicon nitride waveguide quality through femtosecond laser annealing
We present a method for modification of silicon nitride (Si3N4) waveguide resonators using femtosecond laser annealing. The quality (Q) factor of the waveguide resonators can be improved by approximately 1.3 time...
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Open AccessMulti-omics and single cell characterization of cancer immunosenescence landscape
Cellular senescence (CS) is closely related to tumor progression. However, the studies about CS genes across human cancers have not explored the relationship between cancer senescence signature and telomere le...
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Open AccessGeneral negative pressure annealing approach for creating ultra-high-loading single atom catalyst libraries
Catalyst systems populated by high-density single atoms are crucial for improving catalytic activity and selectivity, which can potentially maximize the industrial prospects of heterogeneous single-atom cataly...
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Open AccessReformulating lipid nanoparticles for organ-targeted mRNA accumulation and translation
Fully targeted mRNA therapeutics necessitate simultaneous organ-specific accumulation and effective translation. Despite some progress, delivery systems are still unable to fully achieve this. Here, we reformu...
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Open AccessA high security coding and anti-counterfeiting method based on the nonlinear magnetization response of superparamagnetic nanomaterials
Traditional coding methods based on graphics and digital or magnetic labels have gradually decreased their anti-counterfeiting because of market popularity. This paper presents a new magnetic anti-counterfeiti...
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Open AccessNLRC5 promotes tumorigenesis by regulating the PI3K/AKT signaling pathway in cervical cancer
Cervical cancer (CC) is the fourth most common cancer among women worldwide. NLR Family CARD Domain Containing 5 (NLRC5) plays an important role in tumorigenesis. However, its effect and mechanism in CC remain...
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Open AccessMulti-omic characterization of allele-specific regulatory variation in hybrid pigs
Hybrid map** is a powerful approach to efficiently identify and characterize genes regulated through mechanisms in cis. In this study, using reciprocal crosses of the phenotypically divergent Duroc and Lulai...
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Open AccessA(H2N2) and A(H3N2) influenza pandemics elicited durable cross-reactive and protective antibodies against avian N2 neuraminidases
Human cases of avian influenza virus (AIV) infections are associated with an age-specific disease burden. As the influenza virus N2 neuraminidase (NA) gene was introduced from avian sources during the 1957 pan...
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Open AccessProlonged ventricular repolarization associated with mild cognitive impairment and white matter hyperintensities: a cross-sectional study
Prolonged ventricular repolarization has been associated with cardiovascular disease. We sought to investigate the association of prolonged ventricular repolarization with mild cognitive impairment (MCI) and t...
