1,150 Result(s)
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**-Lin Wang
Biotechnology
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Article
Metabolic engineering of Saccharomyces cerevisiae for high-level production of (+)-ambrein from glucose
(+)-Ambrein is the primary component of ambergris, a rare product found in sperm whales (Physeter microcephalus). Microbial production using sustainable resources is a promising way to replace animal extraction a...
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Synthesis of two Fluorescent Complexes and Their use as Multifunctional Nanomedicine Carriers for Rhabdomyosarcoma Treatment
This study focuses on the design and synthesis of two novel coordination polymers (CPs), named 1 and 2, with excellent fluorescent properties. Their structures were characterized by X-ray single-crystal diffracti...
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TYMS Knockdown Suppresses Cells Proliferation, Promotes Ferroptosis via Inhibits PI3K/Akt/mTOR Signaling Pathway Activation in Triple Negative Breast Cancer
Triple-negative breast cancer (TNBC) is characterized by a grim prognosis and numerous challenges. The objective of our study was to examine the role of thymidylate synthase (TYMS) in TNBC and its impact on fe...
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A rho-type GTPase activating protein affects the growth and development of Cordyceps cicadae
Cordyceps cicadae is recognized for its medicinal properties, attributed to bioactive constituents like polysaccharides and adenosine, which have been shown to improve kidney and liver functions and possess anti-...
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MOF-templated tubular Ni1-xCoxS2-CdS heterojunction with intensified direct Z-scheme charge transmission for highly promoted visible-light photocatalysis
Hollow semiconductor nanostructures with direct Z-scheme heterojunction have significant advantages for photocatalytic reactions, and optimizing the interfacial charge transmission of Z-scheme heterojunction i...
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Nanoparticle delivery for central nervous system diseases and its clinical application
In the treatment of central nervous system (CNS) diseases such as glioma, Alzheimer’s disease (AD) and Parkinson’s disease (PD), drugs are expected to reach specific areas of the brain to achieve the desired e...
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Open AccessApplication of metal-organic frameworks in infectious wound healing
The structural composition and morphological characteristics of the MOFs are described.
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Epitaxial quasi-2D/3D hybrid perovskite heterojunctions for photodetector with enhanced detectivity and stability
Although numerous metal halide perovskite materials have been investigated in the field of optoelectronic, the development of perovskite heterojunctions with exotic structures is still rare. Herein, we report ...
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M2-type macrophage membrane-mediated delivery of Carvedilol nanocomplex for acute liver failure treatment and remodeling inflammatory microenvironment
Interactions of hepatic macrophages with local inflammatory microenvironment is the key factor promoting the development of acute liver failure (ALF). Hence, reprogramming pro-inflammatory M1 into anti-inflamm...
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Article
Single-atomic activation on ZnIn2S4 basal planes boosts photocatalytic hydrogen evolution
The use of single-atom cocatalysts plays a crucial role in enhancing artificial photocatalysis, where the precise construction of stable and efficient single-atom configuration is essential but remains challen...
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Article
Soft multifunctional neurological electronic skin through intrinsically stretchable synaptic transistor
Neurological electronic skin (E-skin) can process and transmit information in a distributed manner that achieves effective stimuli perception, holding great promise in neuroprosthetics and soft robotics. Neuro...
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Article
Materials design and preparation of ultrathin two-dimensional metal halide perovskites
Metal halide perovskites (MHPs) have emerged as highly promising candidates for the next generation of photonics and optoelectronic devices, owing to their prominent optical and excitonic properties, as well a...
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Open AccessPhotosynthetic bacteria-based whole-cell inorganic-biohybrid system for multimodal enhanced tumor radiotherapy
The whole-cell inorganic-biohybrid systems show special functions and wide potential in biomedical application owing to the exceptional interactions between microbes and inorganic materials. However, the hybri...
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Article
MiR-214 promotes the antitumor effect of NK cells in colorectal cancer liver metastasis through USP27X/Bim
Colorectal cancer (CRC) is a common tumor type, and liver metastasis reduces the long-term survival in CRC patients. Natural killer (NK) cells play an important role in anti-tumor immunity. The aim of this stu...
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Open AccessProteomic profiling of prostate cancer reveals molecular signatures under antiandrogen treatment
Tumorigenesis and progression of prostate cancer (PCa) are indispensably dependent on androgen receptor (AR). Antiandrogen treatment is the principal preference for patients with advanced PCa. However, the mol...
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Open AccessMicroneedle delivery system with rapid dissolution and sustained release of bleomycin for the treatment of hemangiomas
Hemangioma of infancy is the most common vascular tumor during infancy and childhood. Despite the proven efficacy of propranolol treatment, certain patients still encounter resistance or face recurrence. The n...
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Article
Fasn involved in the nephrotoxicity induced by polystyrene nanoplastics and the intervention of melatonin through intestinal microbiota-mediated lipid metabolism disorder
Nanoplastics (NPs) can accumulate in the kidney and cause kidney injury, but the multi-organ interaction mechanism and preventive measures of kidney injury are still unclear. In this study, in vivo (60 µg/day, 42...
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Article
Open AccessCold exposure-induced plasma exosomes impair bone mass by inhibiting autophagy
Recently, environmental temperature has been shown to regulate bone homeostasis. However, the mechanisms by which cold exposure affects bone mass remain unclear. In our present study, we observed that exposure...
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Detection methods for antibiotics in wastewater: a review
Antibiotics are widely used as fungicides because of their antibacterial and bactericidal effects. However, it is necessary to control their dosage. If the amount of antbiotics is too much, it cannot be comple...
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Influence of SphK1 on Inflammatory Responses in Lipopolysaccharide-Challenged RAW 264.7 Cells
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are serious respiratory disorders caused by a variety of intrapulmonary and extrapulmonary factors. Their incidence is increasing year by ...
