58 Result(s)
within
**-Lin Wang
Dentistry
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Article
Open AccessCTHRC1 is a prognostic biomarker correlated with immune infiltration in head and neck squamous cell carcinoma
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy worldwide, characterized by high morbidity, high mortality, and poor prognosis. Collagen triple helix repeat containing 1 (CTHR...
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Article
Open AccessExpert consensus on endodontic therapy for patients with systemic conditions
The overall health condition of patients significantly affects the diagnosis, treatment, and prognosis of endodontic diseases. A systemic consideration of the patient’s overall health along with oral condition...
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Waiting for self-healing as a primary management strategy for lower lip mucoceles
Oral mucoceles are most frequently encountered on the lower lip. A variety of treatment options are currently employed, including surgical excision, pharmacological injections, and laser therapy. However, each...
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Open AccessMultiomics profiling reveals VDR as a central regulator of mesenchymal stem cell senescence with a known association with osteoporosis after high-fat diet exposure
The consumption of a high-fat diet (HFD) has been linked to osteoporosis and an increased risk of fragility fractures. However, the specific mechanisms of HFD-induced osteoporosis are not fully understood. Our...
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Medial sural artery perforator free flap versus radial forearm free flap in oral cavity reconstruction and donor site morbidity
Radial Forearm Free flap (RFFF) is widely used in head and neck reconstruction, yet its donor site defect remains a significant drawback. The Medial Sural Artery Perforator Free Flap (MSAPFF) is considered an ...
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Comparing the effectiveness of caries arrest by micro-operative treatment to operative treatment: A 2-year randomized controlled clinical trial
To compare the effectiveness of caries arrest by micro-operative treatment (sealing) to operative treatment (flowable resin composite restoration) through a 2-year randomized controlled clinical trial.
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Article
Open AccessExpert consensus on irrigation and intracanal medication in root canal therapy
Chemical cleaning and disinfection are crucial steps for eliminating infection in root canal treatment. However, irrigant selection or irrigation procedures are far from clear. The vapor lock effect in the api...
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Open AccessThe involvement of Neuregulin-1 in the process of facial nerve injury repair through the utilization of dental pulp stem cells
Facial nerve injury often results in poor prognosis due to the challenging process of nerve regeneration. Neuregulin-1, a human calmodulin, is under investigation in this study for its impact on the reparative...
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Open AccessCD97 inhibits osteoclast differentiation via Rap1a/ERK pathway under compression
Acceleration of tooth movement during orthodontic treatment is challenging, with osteoclast-mediated bone resorption on the compressive side being the rate-limiting step. Recent studies have demonstrated that ...
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Article
Open AccessExpert consensus on odontogenic maxillary sinusitis multi-disciplinary treatment
Odontogenic maxillary sinusitis (OMS) is a subtype of maxillary sinusitis (MS). It is actually inflammation of the maxillary sinus that secondary to adjacent infectious maxillary dental lesion. Due to the lack...
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Open AccessMagnesium promotes vascularization and osseointegration in diabetic states
Diabetes has long been considered a risk factor in implant therapy and impaired wound healing in soft and hard oral tissues. Magnesium has been proved to promote bone healing under normal conditions. Here, we ...
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Article
Open AccessEffects and mechanisms of Porphyromonas gingivalis outer membrane vesicles induced cardiovascular injury
The outer membrane vesicles (OMVs) derived from Porphyromonas gingivalis (P. gingivalis) have long been acknowledged for their crucial role in the initiation of periodontitis. However, the implications of P. ging...
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Article
Open AccessOral cancer cell to endothelial cell communication via exosomal miR-21/RMND5A pathway
Required for meiotic nuclear division 5 homolog A (RMND5A), a novel ubiquitin E3 Ligase, has been reported to correlate with poor prognosis of several cancers. However, its role in endothelial cells has not be...
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Article
The association of aldehyde exposure with the risk of periodontitis: NHANES 2013–2014
Three distinct models were utilized to investigate the combined impacts of serum aldehyde exposure and periodontitis.
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Article
Modified submandibular mandibulotomy approach versus lip-splitting approach in tongue cancer surgery: a retrospective paired-cohort study
The surgical approach for resection and reconstruction of tongue cancer (TSCC) with or without the lip-splitting incision is controversial. This study introduced a modified approach without lip-splitting and t...
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Open AccessOral administration of Bifidobacterium breve improves anti-angiogenic drugs-derived oral mucosal wound healing impairment via upregulation of interleukin-10
Recent studies have suggested that long-term application of anti-angiogenic drugs may impair oral mucosal wound healing. This study investigated the effect of sunitinib on oral mucosal healing impairment in mi...
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Open AccessDental pulp cells cocultured with macrophages aggravate the inflammatory conditions stimulated by LPS
Pulp inflammation is complex interactions between different types of cells and cytokines. To mimic the interactions of different types of cells in inflamed dental pulp tissues, dental pulp cells (DPCs) were co...
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Article
Open AccessExpert consensus on digital guided therapy for endodontic diseases
Digital guided therapy (DGT) has been advocated as a contemporary computer-aided technique for treating endodontic diseases in recent decades. The concept of DGT for endodontic diseases is categorized into sta...
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Open AccessAntitumor effect of toosendanin on oral squamous cell carcinoma via suppression of p-STAT3
Toosendanin (TSN) exhibits potent antitumor activity against various tumor cell lines. However, its efficacy against oral squamous cell carcinoma (OSCC) remains unknown. Here, we investigated the effects of TS...
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Open AccessA systematic review of the accuracy of digital surgical guides for dental implantation
This review aimed to reveal the influence of implant guides on surgical accuracy with regard to supporting types, manufacturing methods and design (including fixation screws and sleeves).
