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  1. Article

    Open Access

    Long-term exercise training down-regulates m6A RNA demethylase FTO expression in the hippocampus and hypothalamus: an effective intervention for epigenetic modification

    Exercise boosts the health of some brain parts, such as the hippocampus and hypothalamus. Several studies show that long-term exercise improves spatial learning and memory, enhances hypothalamic leptin sensiti...

    Shu-**g Liu, Tong-Hui Cai, Chun-Lu Fang, Shao-Zhang Lin, Wen-Qi Yang in BMC Neuroscience (2022)

  2. Article

    Open Access

    Epileptiform activity in mouse hippocampal slices induced by moderate changes in extracellular Mg2+, Ca2+, and K+

    Rodent brain slices—particularly hippocampal slices—are widely used in experimental investigations of epileptiform activity. Oxygenated artificial cerebrospinal fluid (ACSF) is used to maintain slices in vitro...

    Haiyu Liu, Sai Zhang, Liang Zhang in BMC Neuroscience (2021)

  3. No Access

    Protocol

    Library Preparation for Multiplexed Reduced Representation Bisulfite Sequencing with a Universal Adapter

    Reduced representation bisulfite sequencing (RRBS) is an efficient approach for estimating cytosine methylation and hydroxymethylation at single nucleotide resolution with a focus on CpG sites located in CpG i...

    Yong Liu, Alison J. Kriegel, Mingyu Liang in Rat Genomics (2019)

  4. No Access

    Chapter

    “Gating-Spring” Model for Mechanotransduction

    In Chap. 1, we provided a general introduction for mechanotransduction. We feel that before going to the biological details (molecule, structures, etc.), it may he...

    **n Liang, Landi Sun, Zhen Liu in Mechanosensory Transduction in Drosophila Melanogaster (2017)

  5. No Access

    Chapter

    Mechanoreceptors in Drosophila melanogaster

    In Chaps. 1 and 2, we introduced the physiological roles of mechanotransduction and the conceptual design of a mec...

    **n Liang, Landi Sun, Zhen Liu in Mechanosensory Transduction in Drosophila Melanogaster (2017)

  6. No Access

    Chapter

    Overview of Mechanosensory Transduction

    As the start of this booklet, we begin this chapter by providing a definition on “what is mechanosensory transduction” at the cell biological level and listing the fundamental questions in this emerging field....

    **n Liang, Landi Sun, Zhen Liu in Mechanosensory Transduction in Drosophila Melanogaster (2017)

  7. No Access

    Chapter

    Mechanotransduction in Drosophila Mechanoreceptors

    In Chap. 3, we discussed the general physiology of fly mechanoreceptors. You may ask “well, these cells are sensitive to forces, but…how?” Great question! In Chap....

    **n Liang, Landi Sun, Zhen Liu in Mechanosensory Transduction in Drosophila Melanogaster (2017)

  8. No Access

    Chapter

    Drosophila Mechanotransduction Channels

    In Chap. 4, we discussed the working mechanisms of several fly mechanoreceptors. These mechanoreceptors have developed striking structural-mechanical features that...

    **n Liang, Landi Sun, Zhen Liu in Mechanosensory Transduction in Drosophila Melanogaster (2017)

  9. Article

    Open Access

    Expression profiling of human glial precursors

    We have generated gene expression databases for human glial precursors, neuronal precursors, astrocyte precursors and neural stem cells and focused on comparing the profile of glial precursors with that of oth...

    James T Campanelli, Robert W Sandrock, Will Wheatley in BMC Developmental Biology (2008)