-
Article
Open AccessLong-term exercise training down-regulates m6A RNA demethylase FTO expression in the hippocampus and hypothalamus: an effective intervention for epigenetic modification
Exercise boosts the health of some brain parts, such as the hippocampus and hypothalamus. Several studies show that long-term exercise improves spatial learning and memory, enhances hypothalamic leptin sensiti...
-
Article
Open AccessEpileptiform activity in mouse hippocampal slices induced by moderate changes in extracellular Mg2+, Ca2+, and K+
Rodent brain slices—particularly hippocampal slices—are widely used in experimental investigations of epileptiform activity. Oxygenated artificial cerebrospinal fluid (ACSF) is used to maintain slices in vitro...
-
Chapter
“Gating-Spring” Model for Mechanotransduction
In Chap. 1, we provided a general introduction for mechanotransduction. We feel that before going to the biological details (molecule, structures, etc.), it may he...
-
Chapter
Mechanoreceptors in Drosophila melanogaster
In Chaps. 1 and 2, we introduced the physiological roles of mechanotransduction and the conceptual design of a mec...
-
Chapter
Overview of Mechanosensory Transduction
As the start of this booklet, we begin this chapter by providing a definition on “what is mechanosensory transduction” at the cell biological level and listing the fundamental questions in this emerging field....
-
Chapter
Mechanotransduction in Drosophila Mechanoreceptors
In Chap. 3, we discussed the general physiology of fly mechanoreceptors. You may ask “well, these cells are sensitive to forces, but…how?” Great question! In Chap....
-
Chapter
Drosophila Mechanotransduction Channels
In Chap. 4, we discussed the working mechanisms of several fly mechanoreceptors. These mechanoreceptors have developed striking structural-mechanical features that...