233 Result(s)

Article

ATP6V0A1-dependent cholesterol absorption in colorectal cancer cells triggers immunosuppressive signaling to inactivate memory CD8⁺ T cells

Obesity shapes anti-tumor immunity through lipid metabolism; however, the mechanisms underlying how colorectal cancer (CRC) cells utilize lipids to suppress anti-tumor immunity remain unclear. Here, we show th...

Tu-**ong Huang, Hui-Si Huang, Shao-Wei Dong, Jia-Yan Chen… in Nature Communications (2024)

Article

Effects of edge disorder on the stability of quantum oscillations in two-dimensional coupled systems

This paper utilizes the theory of quantum diffusion to analyze the electron probability and spreading width of a wavepacket on each layer in a two-dimensional (2D) coupled system with edge disorder, aiming to ...

Yan-Yan Lu, Zhao-Nan Mu, Yu Huang, Gui-Rong Guo, Han-Hui Li… in Scientific Reports (2024)

Article

Prevalence and genetic diversity of Anaplasma and Ehrlichia in ticks and domesticated animals in Suizhou County, Hubei Province, China

Anaplasma and Ehrlichia are tick-borne bacterial pathogens that cause anaplasmoses and ehrlichioses in humans and animals. In this study, we examined the prevalence of Anaplasma and Ehrlichia species in ticks and...

Ju Tang, Jiao Xu, **ao-hui Liu, Fang-zhi Lv, Qiu-ju Yao… in Scientific Reports (2024)

Article

Robotic versus laparoscopic distal gastrectomy for resectable gastric cancer: a randomized phase 2 trial

Robotic surgery may be an alternative to laparoscopic surgery for gastric cancer (GC). However, randomized controlled trials (RCTs) reporting the differences in survival between these two approaches are curren...

Jun Lu, Bin-bin Xu, Hua-Long Zheng, ** Li, Jian-wei **e… in Nature Communications (2024)

Article

Palladium-catalyzed asymmetric carbene coupling en route to inherently chiral heptagon-containing polyarenes

Develo** facile and direct synthesis routes for enantioselective construction of cyclic π-conjugated molecules is crucial. However, originate chirality from the distorted structure around heptagon-containing...

Huan Zhang, Chuan-Jun Lu, Gao-Hui Cai, Long-Long **, Jia Feng… in Nature Communications (2024)

Article

Proteomic analysis of serum extracellular vesicles from biliary tract infection patients to identify novel biomarkers

Biliary tract infection (BTI), a commonly occurring abdominal disease, despite being extensively studied for its initiation and underlying mechanisms, continues to pose a challenge in the quest for identifying...

Chih-Jung Chang, Yung-Ning Huang, Yang-Bor Lu, Yi Zhang, **-Hua Wu… in Scientific Reports (2024)

Article

Melt-quenched glass formation of a family of metal-carboxylate frameworks

Metal-organic framework (MOF) glasses are an emerging class of glasses which complement traditional inorganic, organic and metallic counterparts due to their hybrid nature. Although a few zeolitic imidazolate ...

Wen-Long Xue, Guo-Qiang Li, Hui Chen, Yu-Chen Han, Li Feng… in Nature Communications (2024)

Article

Global fungal-host interactome map** identifies host targets of candidalysin

Candidalysin, a cytolytic peptide toxin secreted by the human fungal pathogen Candida albicans, is critical for fungal pathogenesis. Yet, its intracellular targets have not been extensively mapped. Here, we perfo...

Tian-Yi Zhang, Yao-Qi Chen, **g-Cong Tan, **-An Zhou… in Nature Communications (2024)

Article

4D printed hydrogel scaffold with swelling-stiffening properties and programmable deformation for minimally invasive implantation

The power of three-dimensional printing in designing personalized scaffolds with precise dimensions and properties is well-known. However, minimally invasive implantation of complex scaffolds is still challeng...

Bo Liu, Hui Li, Fengzhen Meng, Ziyang Xu, Liuzhi Hao, Yuan Yao… in Nature Communications (2024)

Article

Regulation of long-range BMP gradients and embryonic polarity by propagation of local calcium-firing activity

Many amniote vertebrate species including humans can form identical twins from a single embryo, but this only occurs rarely. It has been suggested that the primitive-streak-forming embryonic region emits signa...

Hyung Chul Lee, Nidia M. M. Oliveira, Cato Hastings… in Nature Communications (2024)

Article

SEL1L-HRD1 interaction is required to form a functional HRD1 ERAD complex

The SEL1L-HRD1 protein complex represents the most conserved branch of endoplasmic reticulum (ER)-associated degradation (ERAD). Despite recent advances in both mouse models and humans, in vivo evidence for th...

Liangguang Leo Lin, Huilun Helen Wang, Brent Pederson… in Nature Communications (2024)

Article

Camrelizumab and apatinib plus induction chemotherapy and concurrent chemoradiotherapy in stage N3 nasopharyngeal carcinoma: a phase 2 clinical trial

The antiangiogenic agent apatinib has been shown to clinically improve responses to immune checkpoint inhibitors in several cancer types. Patients with N3 nasopharyngeal carcinoma have a high risk of distant m...

Hu Liang, Yao-Fei Jiang, Guo-Ying Liu, Lin Wang, Jian-Wei Wang… in Nature Communications (2024)

Article

Addendum: Cellular differentiation into hyphae and spores in halophilic archaea

Shu-Kun Tang, **ao-Yang Zhi, Yao Zhang, Kira S. Makarova… in Nature Communications (2024)

Article

Identification of gene signatures and molecular mechanisms underlying the mutual exclusion between psoriasis and leprosy

Leprosy and psoriasis rarely coexist, the specific molecular mechanisms underlying their mutual exclusion have not been extensively investigated. This study aimed to reveal the underlying mechanism responsible...

You-Wang Lu, Rong-**g Dong, Lu-Hui Yang, Jiang Liu, Ting Yang… in Scientific Reports (2024)

Article

AMPKα2 regulates fasting-induced hyperketonemia by suppressing SCOT ubiquitination and degradation

Ketone bodies serve as an energy source, especially in the absence of carbohydrates or in the extended exercise. Adenosine monophosphate (AMP)-activated protein kinase (AMPK) is a crucial energy sensor that re...

Lingxue Zhang, Yanqiao Lu, Junqing An, Yin Wu, Zhixue Liu… in Scientific Reports (2024)

Article

Electrical tuning of branched flow of light

Branched flows occur ubiquitously in various wave systems, when the propagating waves encounter weak correlated scattering potentials. Here we report the experimental realization of electrical tuning of the br...

Shan-shan Chang, Ke-Hui Wu, Si-jia Liu, Zhi-Kang Lin, **-bing Wu… in Nature Communications (2024)

Article

Neoadjuvant camrelizumab and apatinib combined with chemotherapy versus chemotherapy alone for locally advanced gastric cancer: a multicenter randomized phase 2 trial

Prospective evidence regarding the combination of programmed cell death (PD)−1 and angiogenesis inhibitors in treating locally advanced gastric cancer (LAGC) is limited. In this multicenter, randomized, phase ...

Jian-**an Lin, Yi-Hui Tang, Hua-Long Zheng, Kai Ye, Jian-Chun Cai… in Nature Communications (2024)

Article

Reassessing endothelial-to-mesenchymal transition in mouse bone marrow: insights from lineage tracing models

Endothelial cells (ECs) and bone marrow stromal cells (BMSCs) play crucial roles in supporting hematopoiesis and hematopoietic regeneration. However, whether ECs are a source of BMSCs remains unclear. Here, we...

Jia Cao, Ling **, Zi-Qi Yan, **ao-Kai Wang, You-You Li, Zun Wang… in Nature Communications (2023)

Article

Transfer learning with CNNs for efficient prostate cancer and BPH detection in transrectal ultrasound images

Early detection of prostate cancer (PCa) and benign prostatic hyperplasia (BPH) is crucial for maintaining the health and well-being of aging male populations. This study aims to evaluate the performance of tr...

Te-Li Huang, Nan-Han Lu, Yung-Hui Huang, Wen-Hung Twan, Li-Ren Yeh… in Scientific Reports (2023)

Article

Integrated global assessment of the natural forest carbon potential

Forests are a substantial terrestrial carbon sink, but anthropogenic changes in land use and climate have considerably reduced the scale of this system¹. Remote-sensing estimates to quantify carbon losses from gl...

Lidong Mo, Constantin M. Zohner, Peter B. Reich, **g**g Liang, Sergio de Miguel… in Nature (2023)