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Cytolytic Pore-Forming Proteins

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  1. Article

    Erratum: Epigenetic changes in the repression and induction of asparagine synthetase in human leukemic cell lines

    Correction to: Leukemia (2005) 19, 420–426. doi: 10.1038/sj.leu.2403639 It has been identified by the authors that the primer sequences for amplification of human ASY cDNA in quantitative real-time RT-PCR as g...

    Y Ding, Z Li, J D Broome in Leukemia (2005)

  2. Article

    Erratum: Functional characterization of TIP60 sumoylation in UV-irradiated DNA damage response

    Correction to: Oncogene (2008) 27, 931–941; doi:10.1038/sj.onc.1210710; published online 20 August 2007 Owing to typesetting errors, three authors were omitted from the author list. The corrected list and affi...

    Z Cheng, Y Ke, X Ding, F Wang, H Wang, W Wang, K Ahmed, Z Liu, Y Xu in Oncogene (2008)

  3. Article

    High expressions of vascular endothelial growth factor and platelet-derived endothelial cell growth factor predict poor prognosis in alpha-fetoprotein-negative hepatocellular carcinoma patients after curative resection

    Jie Hu, Yang Xu, Zao-Zhuo Shen, Zheng Wang in Journal of Cancer Research and Clinical On… (2009)

  4. Article

    Open Access

    Characterization of High-Fat, Diet-Induced, Non-alcoholic Steatohepatitis with Fibrosis in Rats

    An ideal animal model is necessary for a clear understanding of the etiology, pathogenesis, and mechanisms of human non-alcoholic steatohepatitis (NASH) and for facilitating the design of effective therapy for...

    Zheng-Jie Xu, Jian-Gao Fan, **ao-Dong Ding, Liang Qiao in Digestive Diseases and Sciences (2010)

  5. Article

    Erratum to: Convection-enhanced delivery of free gadolinium with the recombinant immunotoxin MR1-1

    Dale Ding, Charles W. Kanaly, Darrell D. Bigner in Journal of Neuro-Oncology (2010)

  6. Article

    Open Access

    Expression and significance of hypoxia-inducible factor-1 alpha and MDR1/P-glycoprotein in human colon carcinoma tissue and cells

    Hypoxia in tumors is generally associated with chemoresistance and radioresistance. However, the correlation between the heterodimeric hypoxia-inducible factor-1 (HIF-1) and the multidrug resistance (MDR1) gen...

    Zhenyu Ding, Li Yang, **aodong **e in Journal of Cancer Research and Clinical On… (2010)

  7. Article

    Open Access

    HLA-matched sibling transplantation with G-CSF mobilized PBSCs and BM decreases GVHD in adult patients with severe aplastic anemia

    Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an effective treatment for severe aplastic anemia (SAA). However, graft failure and graft-versus-host disease (GVHD) are major causes of the ea...

    Sun Zi-Min, Liu Hui-Lan, Geng Liang-Quan, Wang **n-Bing in Journal of Hematology & Oncology (2010)

  8. Article

    Open Access

    The influence of family history and histological stratification on breast cancer risk in women with benign breast disease: a meta-analysis

    Benign breast disease (BBD) is an important risk factor for subsequent breast cancer. However, it is unclear whether breast cancer risk is higher in cases of atypical ductal hyperplasia (ADH) than atypical lob...

    Wen-Bin Zhou, Dan-Qing Xue, **ao-An Liu in Journal of Cancer Research and Clinical On… (2011)

  9. Article

    Open Access

    GEIRA: gene-environment and gene–gene interaction research application

    The GEIRA (Gene-Environment and Gene–Gene Interaction Research Application) algorithm and subsequent program is dedicated to genome-wide gene-environment and gene–gene interaction analysis. It implements conce...

    Bo Ding, Henrik Källberg, Lars Klareskog in European Journal of Epidemiology (2011)

  10. Article

    Open Access

    Microbiological safety of a novel bio-artificial liver support system based on porcine hepatocytes: a experimental study

    Our institute has developed a novel bio-artificial liver (BAL) support system, based on a multi-layer radial-flow bioreactor carrying porcine hepatocytes and mesenchymal stem cells. It has been shown that porc...

    Bing Han, **ao-lei Shi, Yue Zhang, Xue-hui Chu in European Journal of Medical Research (2012)

  11. Article

    Open Access

    miR-200b restoration and DNA methyltransferase inhibitor block lung metastasis of mesenchymal-phenotype hepatocellular carcinoma

    Epithelial-to-mesenchymal transition (EMT) is associated with poor prognosis and metastasis in hepatocellular carcinoma. We have previously demonstrated an in vivo model of liver cancer in which mesenchymal cells...

    W Ding, H Dang, H You, S Steinway, Y Takahashi, H-G Wang, J Liao, B Stiles in Oncogenesis (2012)

  12. Article

    Open Access

    Effects and mechanism of duodenal-jejunal bypass and sleeve gastrectomy on GLUT2 and glucokinase in diabetic Goto–Kakizaki rats

    The study investigated the effects and mechanism of duodenal-jejunal bypass (DJB) and sleeve gastrectomy (SG) on the expression of liver GLUT2 and glucokinase (GCK) in diabetic rats.

    Zhou Donglei, Lu Liesheng, Jiang Xun, Zhen Chenzhu in European Journal of Medical Research (2012)

  13. Article

    Open Access

    The significance of 18F-FDG PET/CT in secondary hemophagocytic lymphohistiocytosis

    This study was aimed to investigate the significance of 18F-FDG PET/CT in secondary hemophagocytic lymphohistiocytosis (sHLH) patients. A total of 18 patients received 18F-FDG PET/CT scan at initial diagnosis. Al...

    Li-Juan Zhang, Ji Xu, Peng Liu, Chong-Yang Ding in Journal of Hematology & Oncology (2012)

  14. Article

    Open Access

    Homozygous A polymorphism of the complement C1qA 276 correlates with prolonged overall survival in patients with diffuse large B cell lymphoma treated with R-CHOP

    The precise mechanism of action for rituximab (R) is not fully elucidated. Besides antibody-dependent cellular cytotoxicity (ADCC), complements may also play an important role in the clinical response to ritux...

    Xuan **, Huirong Ding, Ning Ding, Zhiying Fu in Journal of Hematology & Oncology (2012)

  15. Article

    The Role of Endocrine Disruptors in the Epigenetics of Reproductive Disease and Dysfunction: Potential Relevance to Humans

    In a murine model, we have linked early life toxicant exposure to reduced uterine sensitivity to progesterone, a phenotype we had previously associated with inflammation in endometriosis patients. Subsequent s...

    Kaylon L. Bruner-Tran, David Resuehr in Current Obstetrics and Gynecology Reports (2012)

  16. Article

    Open Access

    A novel monoclonal antibody of human stem cell factor inhibits umbilical cord blood stem cell ex vivo expansion

    Stem cell factor (SCF) activates hematopoietic stem cell (HSC) self-renewal and is being used to stimulate the ex vivo expansion of HSCs. The mechanism by which SCF supports expansion of HSCs remains poorly un...

    Jie Fan, **nxin Ding, Yong** Jiang in Journal of Hematology & Oncology (2012)

  17. Article

    Open Access

    Tracheal stenting for primary tracheal mucosa-associated lymphoid tissue lymphoma

    Primary tracheal mucosa-associated lymphoid tissue (MALT) lymphoma is extremely rare. We report a 49-year-old female patient with the complaint of dyspnea. Fiberoptic bronchoscopy showed polypoid, variable-siz...

    Juanjuan Ding, Zhuochang Chen, Manli Shi in European Journal of Medical Research (2013)

  18. Article

    Open Access

    Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation

    Embryonal cancer can arise from postnatally persistent embryonal remnant or rest cells, which are uniquely characterized by the absence of p53 mutations. Perinatal overexpression of the MycN oncoprotein in emb...

    M Calao, E O Sekyere, H J Cui, B B Cheung, W D Thomas, J Keating, J B Chen in Oncogene (2013)

  19. Article

    Open Access

    Clinical significance of the uPA system in gastric cancer with peritoneal metastasis

    It has been demonstrated that urokinase-type plasminogen activator (uPA) is involved in tumor cell metastasis by degrading the extracellular matrix. However, there is little direct evidence of clinical uPA sys...

    Youcheng Ding, Hui Zhang, Mingan Zhong in European Journal of Medical Research (2013)

  20. Article

    Open Access

    Analysis of UGT1A1*28 genotype and SN-38 pharmacokinetics for irinotecan-based chemotherapy in patients with advanced colorectal cancer: results from a multicenter, retrospective study in Shanghai

    The UGT1A1*28 polymorphism, although closely linked with CPT-11-related adverse effects, cannot be used alone to guide individualized treatment decisions. However, CPT-11 dosage can be adjusted according to m...

    Xun Cai, Weiguo Cao, Honghua Ding in Journal of Cancer Research and Clinical On… (2013)

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