133 Result(s)
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Article
Meta-analysis of different test indicators: Helicobacter pylori infection and the risk of colorectal cancer
Recent studies have demonstrated the relationship between Helicobacter pylori infection and the risk of colorectal carcinoma. However, the results of these studies remain controversial as the studies were relativ...
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Overexpression of FMNL2 is closely related to metastasis of colorectal cancer
Formin-like 2 (FMNL2) is a member of diaphanous-related formins which can control the actin-dependent processes such as cell motility and invasion. In this study, we investigated the expression of FMNL2 in col...
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Article
A simple colostomy implantation model for evaluating colon cancer
Realistic models of colorectal cancer are necessary to study cancer biology and evaluate therapeutic interventions. Real-time observation and repeated sampling of implanted tumor is difficult to achieve in the...
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Article
The change pattern of SP and NO in the portal vein during the RAIR
To investigate the change pattern of substance P (SP) and nitric oxide (NO) in the portal vein during the recto-anal inhibitory reflex (RAIR), and its physiological significance; the influence of external spla...
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Integration of genetic signature and TNM staging system for predicting the relapse of locally advanced colorectal cancer
To identify potential genetic markers in treated stage II–III colorectal cancer patients and predict 3-year tumor relapse using statistical models based on important clinical factors and significant genetic ma...
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Elevated preoperative neutrophil to lymphocyte ratio predicts risk of recurrence following curative resection for stage IIA colon cancer
Adjuvant chemotherapy for stage II colon cancer remains controversial but may be considered for patients with high-risk features. Recent studies have shown that elevated neutrophil to lymphocyte ratio (NLR) is...
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Article
The study of effect of tea polyphenols on microsatellite instability colorectal cancer and its molecular mechanism
Tea polyphenol has been shown to have anti-colorectal cancer and anti-gene mutation effects, although the mechanism of inhibition of microsatellite instability (MSI) colorectal cancer is not known.
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Erratum: The study of effect of tea polyphenols on microsatellite instability colorectal cancer and its molecular mechanism
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Sedation, analgesia, and cardiorespiratory function in colonoscopy using midazolam combined with fentanyl or propofol
The use of sedatives during colonoscopy remains controversial because of its safety concerns. We compared cardiorespiratory function and sedative and analgesic effects in sedative colonoscopy, using combinatio...
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Lack of association between XPD Lys751Gln and Asp312Asn polymorphisms and colorectal cancer risk: a meta-analysis of case–control studies
The published data on the association between xeroderma pigmentosum group D (XPD) Lys751Gln and Asp312Asn polymorphisms and colorectal cancer remained controversial. The present meta-analysis of literatures wa...
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Open AccessMicrobiological safety of a novel bio-artificial liver support system based on porcine hepatocytes: a experimental study
Our institute has developed a novel bio-artificial liver (BAL) support system, based on a multi-layer radial-flow bioreactor carrying porcine hepatocytes and mesenchymal stem cells. It has been shown that porc...
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Open AccessEffects and mechanism of duodenal-jejunal bypass and sleeve gastrectomy on GLUT2 and glucokinase in diabetic Goto–Kakizaki rats
The study investigated the effects and mechanism of duodenal-jejunal bypass (DJB) and sleeve gastrectomy (SG) on the expression of liver GLUT2 and glucokinase (GCK) in diabetic rats.
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Article
Association of NQO1 rs1800566 polymorphism and the risk of colorectal cancer: a meta-analysis
NAD(P)H:quinone oxidoreductase 1 (NQO1) rs1800566 polymorphism is found to have a lower enzymatic activity, which may result in increased incidence of several kinds of carcinomas including colorectal cancer. R...
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Neuroprotective effect of neurotropin on chronic oxaliplatin-induced neurotoxicity in stage II and stage III colorectal cancer patients: results from a prospective, randomised, single-centre, pilot clinical trial
Oxaliplatin is effective in adjuvant and first-line colorectal cancer chemotherapy. Oxaliplatin-induced severe chronic neurotoxicity is the main dose-limiting adverse event. No standard treatment for oxaliplat...
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Open AccessTracheal stenting for primary tracheal mucosa-associated lymphoid tissue lymphoma
Primary tracheal mucosa-associated lymphoid tissue (MALT) lymphoma is extremely rare. We report a 49-year-old female patient with the complaint of dyspnea. Fiberoptic bronchoscopy showed polypoid, variable-siz...
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Long-term results of laparoscopy-assisted radical right hemicolectomy with D3 lymphadenectomy: clinical analysis with 177 cases
To study the feasibility, safety, and short-/long-term outcomes of laparoscopy-assisted right hemicolectomy with D3 lymphadenectomy for colon cancer.
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Open AccessClinical significance of the uPA system in gastric cancer with peritoneal metastasis
It has been demonstrated that urokinase-type plasminogen activator (uPA) is involved in tumor cell metastasis by degrading the extracellular matrix. However, there is little direct evidence of clinical uPA sys...
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Simvastatin attenuates the lipopolysaccharideinduced inflammatory response of rat pulmonary microvascular endothelial cells by downregulating toll-like receptor 4 expression
The therapeutic potential of simvastatin as an anti-inflammatory agent was explored by investigating its effect on the lipopolysaccharide (LPS)-induced inflammatory response in rat pulmonary microvascular endo...
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Open AccessSelective use of adjuvant chemotherapy for rectal cancer patients with ypN0
The administration of adjuvant chemotherapy for rectal cancer patients with ypN0 is controversial. The purposes of this study were to evaluate the role of adjuvant chemotherapy in ypN0 patients and to optimize...
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Open AccessRisk factors for post-ERCP pancreatitis: a systematic review of clinical trials with a large sample size in the past 10 years
Post- endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) is the most common and most severe complication associated with diagnostic and therapeutic ERCP. A multivariate analysis of risk f...