277 Result(s)
-
Article
Open AccessMir22hg facilitates ferritinophagy-mediated ferroptosis in sepsis by recruiting the m6A reader YTHDC1 and enhancing Angptl4 mRNA stability
Ferritinophagy-mediated ferroptosis plays a crucial role in fighting pathogen aggression. The long non-coding RNA Mir22hg is involved in the regulation of ferroptosis and aberrantly overexpression in lipopolys...
-
Article
Open AccessMicroneedle delivery system with rapid dissolution and sustained release of bleomycin for the treatment of hemangiomas
Hemangioma of infancy is the most common vascular tumor during infancy and childhood. Despite the proven efficacy of propranolol treatment, certain patients still encounter resistance or face recurrence. The n...
-
Article
Open AccessMultifunctional nano-in-micro delivery systems for targeted therapy in fundus neovascularization diseases
Fundus neovascularization diseases are a series of blinding eye diseases that seriously impair vision worldwide. Currently, the means of treating these diseases in clinical practice are continuously evolving a...
-
Article
Open AccessInfluence of liquid properties of colloidal crystals to thermal stability of colloidal crystals on different substrate surfaces through heterogeneous nucleation
The effects of liquid properties, such as pH and conductivity, on the thermal stability of electrostatically interacting colloidal silica crystals generated from heterogeneous nuclei were investigated mainly b...
-
Article
Open AccessOral administration of probiotic spore ghosts for efficient attenuation of radiation-induced intestinal injury
Radiation-induced intestinal injury is the most common side effect during radiotherapy of abdominal or pelvic solid tumors, significantly impacting patients’ quality of life and even resulting in poor prognosi...
-
Article
Open AccessOptimizing a self-solidifying hydrogel as an endoscopically deliverable hydrogel coating system: a proof-of-concept study on porcine endoscopic submucosal dissection-induced ulcers
Endoscopic submucosal dissection (ESD) benefits patients in the early stages of cancer, but it poses various risks of complication. Strategies involving the application of clinically approved products to cover...
-
Article
Open AccessStructural basis of a small monomeric Clivia fluorogenic RNA with a large Stokes shift
RNA-based fluorogenic modules have revolutionized the spatiotemporal localization of RNA molecules. Recently, a fluorophore named 5-((Z)-4-((2-hydroxyethyl)(methyl)amino)benzylidene)-3-methyl-2-((E)-styryl)-3,5-d...
-
Article
Open AccessTitanium dioxide nanoparticles alleviates polystyrene nanoplastics induced growth inhibition by modulating carbon and nitrogen metabolism via melatonin signaling in maize
Nanoplastics, are emerging pollutants, present a potential hazard to food security and human health. Titanium dioxide nanoparticles (Nano-TiO2), serving as nano-fertilizer in agriculture, may be important in alle...
-
Article
Open AccessTernary heterostructure-driven photoinduced electron-hole separation enhanced oxidative stress for triple-negative breast cancer therapy
Zinc oxide nanoparticles (ZnO NPs) stand as among the most significant metal oxide nanoparticles in trigger the formation of reactive oxygen species (ROS) and induce apoptosis. Nevertheless, the utilization of...
-
Article
Open AccessCo-production of 1,3-propanediol and phage phiKpS2 from the glycerol fermentation by Klebsiella pneumoniae
As an alternative to antibiotics in response to antimicrobial-resistant infections, bacteriophages (phages) are garnering renewed interest in recent years. However, the massive preparation of phage is restrict...
-
Article
Open AccessRapid fractionation of corn stover by microwave-assisted protic ionic liquid [TEA][HSO4] for fermentative acetone–butanol–ethanol production
The use of ionic liquids (ILs) to fractionate lignocelluloses for various bio-based chemicals productions is in the ascendant. On this basis, the protic ILs consisting of triethylammonium hydrogen sulfate ([TE...
-
Article
Retraction Note to: MIXED-LIGAND COORDINATION POLYMERS: STRUCTURAL DIVERSITY AND PROTECTIVE EFFECT ON CARDIAC ARREST INDUCED BY ANESTHESIA VIA INDUCING Sirt1 PATHWAY
This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1134/S002247662405024X
-
Article
Open AccessLIFU/MMP-2 dual-responsive release of repurposed drug disulfiram from nanodroplets for inhibiting vasculogenic mimicry and lung metastasis in triple-negative breast cancer
Vasculogenic mimicry (VM), when microvascular channels are formed by cancer cells independent of endothelial cells, often occurs in deep hypoxic areas of tumors and contributes to the aggressiveness and metast...
-
Article
Open AccessBiomimetic MDSCs membrane coated black phosphorus nanosheets system for photothermal therapy/photodynamic therapy synergized chemotherapy of cancer
Photothermal therapy is favored by cancer researchers due to its advantages such as controllable initiation, direct killing and immune promotion. However, the low enrichment efficiency of photosensitizer in tu...
-
Article
Open AccessAnti-EGFR ScFv functionalized exosomes delivering LPCAT1 specific siRNAs for inhibition of lung cancer brain metastases
Brain metastasis (BM) is one of the leading causes of cancer-related deaths in patients with advanced non-small cell lung cancer (NSCLC). However, limited treatments are available due to the presence of the bl...
-
Article
Open AccessRecent advances in the biosynthesis and industrial biotechnology of Gamma-amino butyric acid
GABA (Gamma-aminobutyric acid), a crucial neurotransmitter in the central nervous system, has gained significant attention in recent years due to its extensive benefits for human health. The review focused on ...
-
Article
Open AccessA versatile engineered extracellular vesicle platform simultaneously targeting and eliminating senescent stromal cells and tumor cells to promote tumor regression
Chemotherapy is an important therapeutic approach for malignant tumors for it triggers apoptosis of cancer cells. However, chemotherapy also induces senescence of stromal cells in the tumor microenvironment to...
-
Article
Open AccessSulfonate derivatives bearing an amide unit: design, synthesis and biological activity studies
Pest disasters which occurs on crops is a serious problem that not only cause crop yield loss or even crop failure but can also spread a number of plant diseases.Sulfonate derivatives have been widely used in ...
-
Article
Retraction Note to: A New Co-Based Coordination Polymer with an N-Tripodal Ligand: Synthesis, Crystal Structure, and Inhibition of Human Osteosarcoma Cells
This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1134/S0022476624030223
-
Article
Retraction Note: A water-soluble DsbB variant that catalyzes disulfide-bond formation in vivo
