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Article
Laparoscopic liver resection as a treatment option for intrahepatic cholangiocarcinoma
Laparoscopic liver resection (LLR) remains controversial in the treatment of intrahepatic cholangiocarcinoma (ICC). The aim of the present study is to investigate the outcomes of LLR for ICC compared to open ...
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Article
Open AccessGNUV201, a novel human/mouse cross-reactive and low pH-selective anti-PD-1 monoclonal antibody for cancer immunotherapy
Several PD-1 antibodies approved as anti-cancer therapies work by blocking the interaction of PD-1 with its ligand PD-L1, thus restoring anti-cancer T cell activities. These PD-1 antibodies lack inter-species ...
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Article
Electro-optical properties of solution-processed aluminum–nickel oxide film containing graphene oxide in liquid crystal system
Aluminum–nickel oxide and graphene oxide hybrid films are investigated in this study. The films produced via solution processing were doped with GO at three concentrations: 0, 5, and 15 wt%. The optical transm...
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Article
Open AccessSingle-sided magnetic resonance-based sensor for point-of-care evaluation of muscle
Magnetic resonance imaging is a widespread clinical tool for the detection of soft tissue morphology and pathology. However, the clinical deployment of magnetic resonance imaging scanners is ultimately limited...
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Article
Use of individualized 3D-printed models of pancreatic cancer to improve surgeons’ anatomic understanding and surgical planning
Three-dimensional (3D) printing has been increasingly used to create accurate patient-specific 3D-printed models from medical imaging data. We aimed to evaluate the utility of 3D-printed models in the localiza...
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Chapter and Conference Paper
Reduction of Bubble-Induced Defect in Semiconductor Lithography Process
In this study, methods for suppressing the occurrence of air bubbles in the photoresist (PR) dispensing apparatus of photo lithography system in semiconductor manufacturing process were analyzed. The proposed ...
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Article
Effect of Intraoperatively Detected Bacteriobilia on Surgical Outcomes After Pancreatoduodenectomy: Analysis of a Prospective Database in a Single Institute
Bacteriobilia, the colonization of bacteria in bile, can be caused by obstructive cholangitis or preoperative biliary drainage (PBD), and is not uncommon condition in patients undergoing pancreatoduodenectomy ...
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Article
Open AccessSurgical outcomes and prognostic factors of distal common bile duct adenocarcinoma: chronological analysis in a single high-volume institutional experience
Distal common bile duct (dCBD) cancer is typical indication for pancreaticoduodenectomy (PD). We aimed to retrospectively evaluate surgical outcomes and investigate prognostic factors of dCBD adenocarcinoma fo...
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Article
Open AccessHuman adipose mesenchymal stem cells modulate inflammation and angiogenesis through exosomes
Stem cell-derived exosomes are efficient and safe therapeutic tools for transferring endogenous biological cargo or functional biomolecules for regenerative medicine. The regulation of inflammation and angioge...
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Article
A parallel and accurate method for large-scale image segmentation on a cloud environment
In this paper, we present a parallel algorithm for SLIC on Apache Spark, which we call PSLIC-on-Spark. To this purpose, we have extended the original SLIC algorithm to use the operations in Apache Spark, supporti...
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Article
Minimally Invasive Versus Open Pancreatectomy for Right-Sided and Left-Sided G1/G2 Nonfunctioning Pancreatic Neuroendocrine Tumors: A Multicenter Matched Analysis with an Inverse Probability of Treatment-Weighting Method
Limited evidence exists for the safety and oncologic efficacy of minimally invasive surgery (MIS) for nonfunctioning pancreatic neuroendocrine tumors (NF-PNETs) according to tumor location. This study aimed to...
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Article
Design and Fabrication of a Disposable Nanoactuator Using 3D Printing
Nanoscale patterning has been widely used in various research fields. Conventional technology, however, has its limitations such as high cost and complicated processes. Recently, many alternative processes hav...
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Article
Human Adipose Mesenchymal Stem Cell-Derived Exosomes: A Key Player in Wound Healing
Human adipose-derived mesenchymal stem cells (AMSCs) are an attractive resource for wound healing because their regenerative capacity improves injury repair. Recently, stem cell-derived exosomes have been show...
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Article
Open AccessRisk prediction for malignant intraductal papillary mucinous neoplasm of the pancreas: logistic regression versus machine learning
Most models for predicting malignant pancreatic intraductal papillary mucinous neoplasms were developed based on logistic regression (LR) analysis. Our study aimed to develop risk prediction models using machi...
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Article
Comparative study of laparoscopic versus open technique for simultaneous resection of colorectal cancer and liver metastases with propensity score analysis
Laparoscopic liver resection for metastatic colorectal cancer (CRC) remains controversial. The objective of this study was to compare the short-term and mid-term outcomes of patients with CRC undergoing laparo...
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Article
Open AccessSingle-cell transcriptome analysis of tumor and stromal compartments of pancreatic ductal adenocarcinoma primary tumors and metastatic lesions
Solid tumors such as pancreatic ductal adenocarcinoma (PDAC) comprise not just tumor cells but also a microenvironment with which the tumor cells constantly interact. Detailed characterization of the cellular ...
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Article
Recurrence After Resection for Intraductal Papillary Neoplasm of Bile Duct (IPNB) According to Tumor Location
No studies have yet analyzed the characteristics of recurrence after resection for intraductal papillary neoplasm of bile duct (IPNB) based on tumor location. We analyzed the patterns, timing, and risk factors...
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Article
Characteristics of Integrated Air Control and Low-Pressure Exhaust Gas Recirculation Valve for Diesel Engines
The purpose of this study is to investigate the characteristics of a newly introduced integrated exhaust gas recirculation (EGR) valve. Traditionally, a exhaust-pressure regulating valve is installed to increa...
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Article
Open AccessThe efficacy of polyglycolic acid felt reinforcement in preventing postoperative pancreatic fistula after pancreaticojejunostomy in patients with main pancreatic duct less than 3 mm in diameter and soft pancreas undergoing pancreatoduodenectomy (PLANET-PJ trial): study protocol for a multicentre randomized phase III trial in Japan and Korea
Partial pancreatoduodenectomy is performed for malignant and benign diseases of the pancreatic head region. The procedure is considered highly difficult and highly invasive. Postoperative pancreatic fistula (P...
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Article
Development of a Single-Suction Double-Discharge Automatic Transmission Oil Pump for Power-Consumption Reduction
The high power consumption of the automatic transmission oil pump has led to the undertaking of efficiency improvement studies over a number of decades. For the unique idea of the present paper, a single autom...
