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Article
Vagus nerve electrical stimulation in the recovery of upper limb motor functional impairment after ischemic stroke
Ischemic stroke (IS) is characterized by high mortality, disability rates, and a high risk of recurrence. Motor dysfunction, such as limb hemiparesis, dysphagia, auditory disorders, and speech disorders, usual...
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Article
Research progress of epileptic seizure prediction methods based on EEG
At present, at least 30% of refractory epilepsy patients in the world cannot be effectively controlled and treated. The suddenness and unpredictability of seizures greatly affect the physical and mental health...
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Article
Long-range and cross-frequency neural modulation of gamma flicker on vigilance decrement
Vigilance decrement is a ubiquitous problem in attention-demanding tasks. Therefore, it is significant to develop neuromodulation methods to mitigate the negative neural effect of vigilance decrement. As one o...
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Article
Detection of dynamic changes of electrodermal activity to predict the classroom performance of college students
It is emphasized in the Self-regulated learning (SRL) framework that self-monitoring of learning state is vital for students to keep effective in studying. However, it’s still challenging to get an accurate an...
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Article
Open AccessTranscranial alternating current stimulation ameliorates emotional attention through neural oscillations modulation
Numerous clinical reports have suggested that psychopathy like schizophrenia, anxiety and depression is accompanied by early attentional abnormalities in emotional processing. Recently, the efficacy of transcr...
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Article
CDK6 is a novel predictive and prognosis biomarker correlated with immune infiltrates in multiple human neoplasms, including small cell lung carcinoma
The roles of cyclin-dependent kinase 6 (CDK6) in various cancers, including small cell lung carcinoma (SCLC), remain unclear. Here, 111,54 multi-center samples were investigated to determine the expression, clini...
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Article
ITGB4 Serves as an Identification and Prognosis Marker Associated with Immune Infiltration in Small Cell Lung Carcinoma
Integrin beta 4 (ITGB4) is a vital factor for numerous cancers. However, no reports regarding ITGB4 in small cell lung carcinoma (SCLC) have been found in the existing literature. This study systematically invest...
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Article
Knockdown of LINC01087 inhibits gastric cancer malignant behavior by regulating the miR-135a-5p/CAAP1 axis
Long noncoding RNAs play important roles in the occurrence and development of many malignant cancers. This study focuses on the effects of LINC01087 on gastric cancer and its underlying mechanism. In the prese...
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Article
Open AccessHypofunction of directed brain network within alpha frequency band in depressive patients: a graph-theoretic analysis
Directed brain networks may provide new insights into exploring physiological mechanism and neuromarkers for depression. This study aims to investigate the abnormalities of directed brain networks in depressiv...
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Article
Sensorimotor rhythm neurofeedback training relieves anxiety in healthy people
Timely relief of anxiety in healthy people is important, but there is little research on this topic at present. Neurofeedback training allows subjects to regulate their specific brain activities autonomously a...
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Article
Open AccessTargeting NAD+: is it a common strategy to delay heart aging?
Heart aging is the main susceptible factor to coronary heart disease and significantly increases the risk of heart failure, especially when the aging heart is suffering from ischemia-reperfusion injury. Numero...
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Article
Open AccessObacunone alleviates ferroptosis during lipopolysaccharide-induced acute lung injury by upregulating Nrf2-dependent antioxidant responses
Acute lung injury (ALI) has received considerable attention in the field of intensive care as it is associated with a high mortality rate. Obacunone (OB), widely found in citrus fruits, is a natural bioactive ...
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Article
Open AccessCircNEIL3 mediates pyroptosis to influence lung adenocarcinoma radiotherapy by upregulating PIF1 through miR-1184 inhibition
Circular RNAs (circRNAs) belong to an abundant category of non-coding RNAs that are stable and specific, and thus have great potential in cancer treatment. However, little is known about the role of circRNAs d...
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Article
Correction to: Review of brain encoding and decoding mechanisms for EEG-based brain–computer interface
A correction to this paper has been published: https://doi.org/10.1007/s11571-021-09686-x
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Article
Review of brain encoding and decoding mechanisms for EEG-based brain–computer interface
A brain–computer interface (BCI) can connect humans and machines directly and has achieved successful applications in the past few decades. Many new BCI paradigms and algorithms have been developed in recent y...
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Article
Immune landscape and therapeutic strategies: new insights into PD-L1 in tumors
PD-1/PD-L1 axis represents an important target for renormalizing and resetting anti-tumor immunity in cancer patients. Currently, anti-PD-1/PD-L1 therapy has been applied in a broad spectrum of tumors and has ...
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Article
Prolyl hydroxylase 3 controls the intestine goblet cell generation through stabilizing ATOH1
Intestinal epithelia self-renew constantly and generate differentiated cells such as secretary goblet cells. The intestine goblet cells secrete gel-forming mucins that form mucus to create a barrier of defense...
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Article
PtNPs-GNPs-MWCNTs-β-CD nanocomposite modified glassy carbon electrode for sensitive electrochemical detection of folic acid
A novel electrochemical sensor, platinum nanoparticles/graphene nanoplatelets/multi-walled carbon nanotubes/β-cyclodextrin composite (PtNPs-GNPs-MWCNTs-β-CD) modified carbon glass electrode (GCE), was fabricat...
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Article
Open AccessThe PAX6-ZEB2 axis promotes metastasis and cisplatin resistance in non-small cell lung cancer through PI3K/AKT signaling
Paired-box 6 (PAX6) is an important transcription factor required for the function of human neuroectodermal epithelial tissues. Previous studies have suggested that it is also expressed in several types of tum...
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Article
Artemisinin biosynthesis in Artemisia annua and metabolic engineering: questions, challenges, and perspectives
Artemisinin-based combination therapy (ACT) forms the frontline treatment of malaria. Artemisinin, an endoperoxide sesquiterpenoid lactone biosynthesized by Artemisia annua, is the effective medicine that kills m...