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Article
Vagus nerve electrical stimulation in the recovery of upper limb motor functional impairment after ischemic stroke
Ischemic stroke (IS) is characterized by high mortality, disability rates, and a high risk of recurrence. Motor dysfunction, such as limb hemiparesis, dysphagia, auditory disorders, and speech disorders, usual...
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Article
Research progress of epileptic seizure prediction methods based on EEG
At present, at least 30% of refractory epilepsy patients in the world cannot be effectively controlled and treated. The suddenness and unpredictability of seizures greatly affect the physical and mental health...
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Article
Long-range and cross-frequency neural modulation of gamma flicker on vigilance decrement
Vigilance decrement is a ubiquitous problem in attention-demanding tasks. Therefore, it is significant to develop neuromodulation methods to mitigate the negative neural effect of vigilance decrement. As one o...
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Article
Detection of dynamic changes of electrodermal activity to predict the classroom performance of college students
It is emphasized in the Self-regulated learning (SRL) framework that self-monitoring of learning state is vital for students to keep effective in studying. However, it’s still challenging to get an accurate an...
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Article
Open AccessTranscranial alternating current stimulation ameliorates emotional attention through neural oscillations modulation
Numerous clinical reports have suggested that psychopathy like schizophrenia, anxiety and depression is accompanied by early attentional abnormalities in emotional processing. Recently, the efficacy of transcr...
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Article
The tumor immune microenvironment of nasopharyngeal carcinoma after gemcitabine plus cisplatin treatment
Gemcitabine plus cisplatin (GP) chemotherapy is the standard of care for nasopharyngeal carcinoma (NPC). However, the mechanisms underpinning its clinical activity are unclear. Here, using single-cell RNA sequ...
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Article
Open AccessHypofunction of directed brain network within alpha frequency band in depressive patients: a graph-theoretic analysis
Directed brain networks may provide new insights into exploring physiological mechanism and neuromarkers for depression. This study aims to investigate the abnormalities of directed brain networks in depressiv...
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Article
Sensorimotor rhythm neurofeedback training relieves anxiety in healthy people
Timely relief of anxiety in healthy people is important, but there is little research on this topic at present. Neurofeedback training allows subjects to regulate their specific brain activities autonomously a...
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Article
Correction to: Review of brain encoding and decoding mechanisms for EEG-based brain–computer interface
A correction to this paper has been published: https://doi.org/10.1007/s11571-021-09686-x
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Article
Review of brain encoding and decoding mechanisms for EEG-based brain–computer interface
A brain–computer interface (BCI) can connect humans and machines directly and has achieved successful applications in the past few decades. Many new BCI paradigms and algorithms have been developed in recent y...
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Article
Association between thyroglobulin polymorphisms and autoimmune thyroid disease: a systematic review and meta-analysis of case–control studies
Emerging evidence revealed that thyroglobulin (TG) contributes to the development of autoimmune disease, and the relationship between TG and autoimmune thyroid disease (AITD) is still controversial. The aim of...
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Article
CZ-7, a new derivative of Claulansine F, ameliorates 2VO-induced vascular dementia in rats through a Nrf2-mediated antioxidant responses
Vascular dementia (VD) results from accumulated damage in the vascular system, which is characterized by progressive impairments in memory and cognition and is second only to Alzheimer’s disease (AD) in preval...
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Article
Open AccessReduced protocadherin17 expression in leukemia stem cells: the clinical and biological effect in acute myeloid leukemia
Leukemia stem cell (LSC)-enriched genes have been shown to be highly prognostic in acute myeloid leukemia (AML). However, the prognostic value of tumor suppressor genes (TSGs) that are repressed early in LSC r...
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Article
Polygalasaponin XXXII, a triterpenoid saponin from Polygalae Radix, attenuates scopolamine-induced cognitive impairments in mice
Recent studies show that the extract of a Chinese herb Polygalae Radix exerts cognition-enhancing actions in rats and humans. The aim of this study was to characterize the pharmacological profiles of active co...
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Article
Active surveillance of renal masses in von Hippel-Lindau disease: growth rates and clinical outcome over a median follow-up period of 56 months
To evaluate the natural outcome of a surveillance strategy for enhancing renal masses associated with von Hippel-Lindau disease (VHL). From January 1988 to June 2011, a watchful waiting strategy was carried ou...
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Article
Polygalasaponin F induces long-term potentiation in adult rat hippocampus via NMDA receptor activation
To investigate the effect and underlying mechanisms of polygalasaponin F (PGSF), a triterpenoid saponin isolated from Polygala japonica, on long-term potentiation (LTP) in hippocampus dentate gyrus (DG) of anesth...
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Article
Protective effect of Bu-7, a flavonoid extracted from Clausena lansium, against rotenone injury in PC12 cells
To investigate the protective effect and underlying mechanisms of Bu-7, a flavonoid isolated from the leaves of Clausena lansium, against rotenone-induced injury in PC12 cells.
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Article
MicroRNA-155 Regulates Inflammatory Cytokine Production in Tumor-associated Macrophages via Targeting C/EBPβ
Macrophages (Mφ) are prominent components of solid tumors and exhibit distinct phenotypes in different microenvironments. We have recently found that tumors can alter the normal developmental process of Mφ to ...
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Article
Polygalasaponin XXXII from Polygala tenuifolia root improves hippocampal-dependent learning and memory
The aim of this study was to investigate the cognition-enhancing activity and underlying mechanisms of a triterpenoid saponin (polygalasaponin XXXII, PGS32) isolated from the roots of Polygala tenuifolia Willd.
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Article
Suppression of inflammatory cytokine production and oxidative stress by CO-releasing molecules—liberated CO in the small intestine of thermally-injured mice
To determine whether carbon monoxide (CO)-releasing molecules-liberated CO suppress inflammatory cytokine production and oxidative stress in the small intestine of burnt mice.