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Article
Vagus nerve electrical stimulation in the recovery of upper limb motor functional impairment after ischemic stroke
Ischemic stroke (IS) is characterized by high mortality, disability rates, and a high risk of recurrence. Motor dysfunction, such as limb hemiparesis, dysphagia, auditory disorders, and speech disorders, usual...
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Article
Research progress of epileptic seizure prediction methods based on EEG
At present, at least 30% of refractory epilepsy patients in the world cannot be effectively controlled and treated. The suddenness and unpredictability of seizures greatly affect the physical and mental health...
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Article
Long-range and cross-frequency neural modulation of gamma flicker on vigilance decrement
Vigilance decrement is a ubiquitous problem in attention-demanding tasks. Therefore, it is significant to develop neuromodulation methods to mitigate the negative neural effect of vigilance decrement. As one o...
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Article
Detection of dynamic changes of electrodermal activity to predict the classroom performance of college students
It is emphasized in the Self-regulated learning (SRL) framework that self-monitoring of learning state is vital for students to keep effective in studying. However, it’s still challenging to get an accurate an...
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Article
Open AccessTranscranial alternating current stimulation ameliorates emotional attention through neural oscillations modulation
Numerous clinical reports have suggested that psychopathy like schizophrenia, anxiety and depression is accompanied by early attentional abnormalities in emotional processing. Recently, the efficacy of transcr...
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Article
The tumor immune microenvironment of nasopharyngeal carcinoma after gemcitabine plus cisplatin treatment
Gemcitabine plus cisplatin (GP) chemotherapy is the standard of care for nasopharyngeal carcinoma (NPC). However, the mechanisms underpinning its clinical activity are unclear. Here, using single-cell RNA sequ...
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Article
Open AccessHypofunction of directed brain network within alpha frequency band in depressive patients: a graph-theoretic analysis
Directed brain networks may provide new insights into exploring physiological mechanism and neuromarkers for depression. This study aims to investigate the abnormalities of directed brain networks in depressiv...
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Article
Sensorimotor rhythm neurofeedback training relieves anxiety in healthy people
Timely relief of anxiety in healthy people is important, but there is little research on this topic at present. Neurofeedback training allows subjects to regulate their specific brain activities autonomously a...
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Article
Correction to: Review of brain encoding and decoding mechanisms for EEG-based brain–computer interface
A correction to this paper has been published: https://doi.org/10.1007/s11571-021-09686-x
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Article
VEGF Modulates the Neural Dynamics of Hippocampal Subregions in Chronic Global Cerebral Ischemia Rats
Theta and gamma rhythms in hippocampus are important to cognitive performance. The cognitive impairments following cerebral ischemia is linked with the dysfunction of theta and gamma oscillations. As the prima...
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Article
Review of brain encoding and decoding mechanisms for EEG-based brain–computer interface
A brain–computer interface (BCI) can connect humans and machines directly and has achieved successful applications in the past few decades. Many new BCI paradigms and algorithms have been developed in recent y...
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Article
EEG-Based Anxious States Classification Using Affective BCI-Based Closed Neurofeedback System
Anxiety disorder is one of the psychiatric disorders that involves extreme fear or worry, which can change the balance of chemicals in the brain. To the best of our knowledge, the evaluation of anxiety state i...
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Article
Dynamic Brain Responses Modulated by Precise Timing Prediction in an Opposing Process
The brain function of prediction is fundamental for human beings to shape perceptions efficiently and successively. Through decades of effort, a valuable brain activation map has been obtained for prediction. ...
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Article
Downregulation of Adhesion Molecule CHL1 in B Cells but Not T Cells of Patients with Major Depression and in the Brain of Mice with Chronic Stress
Depression is a common serious mental disorder with unclear pathogenesis. Currently, specific diagnostic biomarkers are yet to be characterized. The close homolog of L1 (CHL1) is a L1 family cell adhesion mole...
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Article
Open AccessContributions of Age-Related Thymic Involution to Immunosenescence and Inflammaging
Immune system aging is characterized by the paradox of immunosenescence (insufficiency) and inflammaging (over-reaction), which incorporate two sides of the same coin, resulting in immune disorder. Immunosenes...
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Article
Open AccessDown-regulation of miR-29c is a prognostic biomarker in acute myeloid leukemia and can reduce the sensitivity of leukemic cells to decitabine
MicroRNA-29c (miR-29c) is abnormally expressed in several cancers and serves as an important predictor of tumor prognosis. Herein, we investigate the effects of abnormal miR-29c expression and analyze its clin...
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Article
Association between thyroglobulin polymorphisms and autoimmune thyroid disease: a systematic review and meta-analysis of case–control studies
Emerging evidence revealed that thyroglobulin (TG) contributes to the development of autoimmune disease, and the relationship between TG and autoimmune thyroid disease (AITD) is still controversial. The aim of...
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Article
CZ-7, a new derivative of Claulansine F, ameliorates 2VO-induced vascular dementia in rats through a Nrf2-mediated antioxidant responses
Vascular dementia (VD) results from accumulated damage in the vascular system, which is characterized by progressive impairments in memory and cognition and is second only to Alzheimer’s disease (AD) in preval...
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Article
Open AccessReduced protocadherin17 expression in leukemia stem cells: the clinical and biological effect in acute myeloid leukemia
Leukemia stem cell (LSC)-enriched genes have been shown to be highly prognostic in acute myeloid leukemia (AML). However, the prognostic value of tumor suppressor genes (TSGs) that are repressed early in LSC r...
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Article
Oxymatrine Sensitizes the HaCaT Cells to the IFN-γ Pathway and Downregulates MDC, ICAM-1, and SOCS1 by Activating p38, JNK, and Akt
Decreased interferon (IFN)-γ levels and increased levels of macrophage-derived chemokine (MDC) and intercellular adhesion molecule (ICAM)-1 are known to be involved in allergic skin diseases, such as eczema an...