940 Result(s)

Article

Use of intravenous immune globulin in patients receiving bone marrow transplants

Patients undergoing bone marrow transplantation for acute leukemia or aplastic anemia are a great risk for the development of interstitial pneumonia associated with the cytomegalovirus (CMV). Passive immunizat...

Drew J. Winston, Winston G. Ho, Lucille E. Rasmussen… in Journal of Clinical Immunology (1982)

Chapter

Protection of Cats from Infectious Peritonitis by Vaccination with a Recombinant Raccoon Poxvirus Expressing the Nucleocapsid Gene of Feline Infectious Peritonitis Virus

Feline Infectious Peritonitis Virus (FIPV) is a coronavirus that induces an often fatal, systemic infection in cats. Various vaccines designed to prevent FIPV infection have been shown to exacerbate the diseas...

T. L. Wasmoen, N. P. Kadakia, R. C. Unfer, B. L. Fickbohm… in Corona- and Related Viruses (1995)

Chapter

Efficacy of an Inactivated Vaccine against Clinical Disease Caused by Canine Coronavirus

Canine Coronavirus (CCV) is a causative agent of diarrhea in dogs. The reproduction of severe clinical disease with experimental CCV infection has been difficult. We have recently developed a CCV challenge mod...

R. Fulker, T. Wasmoen, R. Atchison, H-J. Chu, W. Acree in Corona- and Related Viruses (1995)

Article

Reliability and validity of tympanic temperature measurement in persons with high spinal cord injuries

Tympanic temperature measurements in the able bodied have been well studied and validated in previous investigations. This validation has not been studied in individuals with high spinal cord injuries where au...

A Chu, R S Burnham in Spinal Cord (1995)

Article

Intracavernous injection of prostaglandin e1 in spinal cord injured patients with erectile dysfunction. A preliminary report

Our experience with intracavernous injection of prostaglandin E1 in spinal cord injured patients with neurogenic erectile dysfunction included 15 men. They received testing dosage starting from 5 µg with increasi...

S F T Tang, N K Chu, M K Wong in Spinal Cord (1995)

Article

Microsatellite instability, Epstein–Barr virus, mutation of type II transforming growth factor β receptor and BAX in gastric carcinomas in Hong Kong Chinese

Microsatellite instability (MI), the phenotypic manifestation of mismatch repair failure, is found in a proportion of gastric carcinomas. Little is known of the links between MI and Epstein–Barr virus (EBV) st...

S Y Leung, S T Yuen, L P Chung, K M Chu, M P Wong… in British Journal of Cancer (1999)

Article

Activation of monocytes, T-lymphocytes and plasma inflammatory markers in angina patients

Inflammation and activation of immune cells have important roles in the pathogenesis of atherosclerosis. We analyzed the plasma levels of inflammatory markers and the degree of activation of peripheral blood m...

Won-Ha Lee, Yoon Lee, Jong-Ran Kim, **-A Chu… in Experimental & Molecular Medicine (1999)

Article

Genomic-scale genetic expression profiles of oral cancers

Eduardo Mendez, Chen Chu in Nature Genetics (2001)

Article

Mitochondrial DNA polymorphisms in Yunnan nationalities in China

Nucleotide sequences of the D-loop region of human mitochondrial DNA from four Yunnan nationalities, Dai, Wa, Lahu, and Tibetan, were analyzed. Based on a comparison of 563-bp sequences in 99 people, 66 diffe...

Y. P. Qian, Z. -T. Chu, Q. Dai, C.-D. Wei, J. Y. Chu… in Journal of Human Genetics (2001)

Article

Method for non-invasively recording electrocardiograms in conscious mice

The rapid increase in the development of mouse models is resulting in a growing demand for non-invasive physiological monitoring of large quantities of mice. Accordingly, we developed a new system for recordin...

Victor Chu, Jose M Otero, Orlando Lopez, James P Morgan, Ivo Amende… in BMC Physiology (2001)

Article

Specific and nonspecific NK cell activation during virus infection

The natural killer (NK) cell activation receptor Ly49H is required for resistance to murine cytomegalovirus (MCMV). We show here that NK cell proliferation and production of interferon-γ (IFN-γ) was not depend...

Ayotunde O. Dokun, Sung** Kim, Hamish R.C. Smith, Hyun-Seok P. Kang… in Nature Immunology (2001)

Article

Investigations on a clinically and functionally unusual and novel germline p53 mutation

This report describes an individual with a rare choroid plexus papilloma in adulthood (age 29) after earlier having an osteosarcoma (age 22). The results from this study, and others, suggest that it may be adv...

J Rutherford, C E Chu, P M Duddy, R S Charlton, P Chumas… in British Journal of Cancer (2002)

Article

The κB transcriptional enhancer motif and signal sequences of V(D)J recombination are targets for the zinc finger protein HIVEP3/KRC: a site selection amplification binding study

The ZAS family is composed of proteins that regulate transcription via specific gene regulatory elements. The amino-DNA binding domain (ZAS-N) and the carboxyl-DNA binding domain (ZAS-C) of a representative fa...

Carl E Allen, Chi-ho Mak, Lai-Chu Wu in BMC Immunology (2002)

Article

Aberrant caspase-activated DNase (CAD) transcripts in human hepatoma cells

The gene of caspase-activated DNase (CAD), the key enzyme for nucleosome cleavage during apoptosis, is mapped at chromosome 1p36, a region usually associated with hemizygous deletions in human cancers, particu...

S Y Hsieh, S F Liaw, S N Lee, P S Hsieh, K H Lin, C M Chu… in British Journal of Cancer (2003)

Article

Association of HLA class I with severe acute respiratory syndrome coronavirus infection

The human leukocyte antigen (HLA) system is widely used as a strategy in the search for the etiology of infectious diseases and autoimmune disorders. During the Taiwan epidemic of severe acute respiratory synd...

Marie Lin, Hsiang-Kuang Tseng, Jean A Trejaut, Hui-Lin Lee… in BMC Medical Genetics (2003)

Article

Constitutional activation of IL-6-mediated JAK/STAT pathway through hypermethylation of SOCS-1 in human gastric cancer cell line

The interleukin-mediated Janus kinase (JAK)/STAT pathway plays a crucial role in carcinogenesis. Recently, increased STAT3 activity was found in hepatocellular carcinoma and multiple myeloma in which there was...

K F To, M W Y Chan, W K Leung, E K W Ng, J Yu, A H C Bai… in British Journal of Cancer (2004)

Article

Modulating HIV-1 replication by RNA interference directed against human transcription elongation factor SPT5

Several cellular positive and negative elongation factors are involved in regulating RNA polymerase II processivity during transcription elongation in human cells. In recruiting several of these regulatory fac...

Yueh-Hsin **, Chia-ying Chu, Hong Cao, Jean-Marc Jacque, Mario Stevenson… in Retrovirology (2004)

Article

Persistent shedding of viable SARS-CoV in urine and stool of SARS patients during the convalescent phase

In order to further the present knowledge of the emerging severe acute respiratory syndrome-associated coronavirus (SARS-CoV), 486 different specimens from 54 patients with a clinical diagnosis of SARS were in...

D. Xu, Z. Zhang, L. **, F. Chu, Y. Mao… in European Journal of Clinical Microbiology … (2005)

Article

Mutations of PIK3CAin gastric adenocarcinoma

Activation of the phosphatidylinositol 3-kinase (PI3K) through mutational inactivation of PTEN tumour suppressor gene is common in diverse cancer types, but rarely reported in gastric cancer. Recently, mutations ...

Vivian Sze Wing Li, Chi Wai Wong, Tsun Leung Chan, Agnes Sze Wah Chan… in BMC Cancer (2005)

Article

Low RET mutation frequency and polymorphism analysis of the RET and EDNRB genes in patients with Hirschsprung disease in Taiwan

Hirschsprung disease (HSCR), or congenital intestinal aganglionosis, is a relatively common disorder characterized by the absence of ganglion cells in the nerve plexuses of the lower digestive tract, resulting...

Trang-Tiau Wu, Tsui-Wei Tsai, Chao-Ta Chu, Zen-Fung Lee… in Journal of Human Genetics (2005)