172 Result(s)
within
Biomedicine
Immunology
**** Chu
-
Article
Use of intravenous immune globulin in patients receiving bone marrow transplants
Patients undergoing bone marrow transplantation for acute leukemia or aplastic anemia are a great risk for the development of interstitial pneumonia associated with the cytomegalovirus (CMV). Passive immunizat...
-
Chapter
Protection of Cats from Infectious Peritonitis by Vaccination with a Recombinant Raccoon Poxvirus Expressing the Nucleocapsid Gene of Feline Infectious Peritonitis Virus
Feline Infectious Peritonitis Virus (FIPV) is a coronavirus that induces an often fatal, systemic infection in cats. Various vaccines designed to prevent FIPV infection have been shown to exacerbate the diseas...
-
Chapter
Efficacy of an Inactivated Vaccine against Clinical Disease Caused by Canine Coronavirus
Canine Coronavirus (CCV) is a causative agent of diarrhea in dogs. The reproduction of severe clinical disease with experimental CCV infection has been difficult. We have recently developed a CCV challenge mod...
-
Article
Specific and nonspecific NK cell activation during virus infection
The natural killer (NK) cell activation receptor Ly49H is required for resistance to murine cytomegalovirus (MCMV). We show here that NK cell proliferation and production of interferon-γ (IFN-γ) was not depend...
-
Article
Open AccessThe κB transcriptional enhancer motif and signal sequences of V(D)J recombination are targets for the zinc finger protein HIVEP3/KRC: a site selection amplification binding study
The ZAS family is composed of proteins that regulate transcription via specific gene regulatory elements. The amino-DNA binding domain (ZAS-N) and the carboxyl-DNA binding domain (ZAS-C) of a representative fa...
-
Chapter and Conference Paper
Fluorescence Dequenching Assays of Coronavirus Fusion
-
Chapter and Conference Paper
Avian Infectious Bronchitis Virus Enters Cells Via the Endocytic Pathway
-
Article
Baculovirus ETL promoter acts as a shuttle promoter between insect cells and mammalian cells
To identify a shuttle promoter that can mediate gene expression in both insect cells and mammalian cells to facilitate the development of a baculovirus vector-based mammalian cell gene delivery vehicle.
-
Article
Pranlukast reduces neutrophil but not macrophage/microglial accumulation in brain after focal cerebral ischemia in mice
To determine whether pranlukast, a cysteinyl leukotriene receptor-1 antagonist, exerts an anti-inflammatory effect on focal cerebral ischemia in mice.
-
Article
Role of rat liver cytochrome P450 3A and 2D in metabolism of imrecoxib
To investigate the in vitro metabolism of imrecoxib in rat liver microsomes and to identify the cytochrome P450 (CYP) forms involved in its metabolism.
-
Article
Formation of 4′-carboxyl acid metabolite of imrecoxib by rat liver microsomes
Imrecoxib is a novel and moderately selective COX-2 inhibitor. The aim of the present in vitro investigation was to study the formation of the major metabolite 4′-carboxylic acid imrecoxib (M2) and identify the e...
-
Article
Caffeic acid ameliorates early and delayed brain injuries after focal cerebral ischemia in rats
To investigate the effects of caffeic acid on early and delayed injuries after focal cerebral ischemia in rats, and the possible relation to 5-lipoxygenase inhibition.
-
Article
Antisense oligonucleotide targeting p53 increased apoptosis of MCF-7 cells induced by ionizing radiation
To investigate the effect of antisense compounds (AS) targeting human p53 mRNA on radiosensitivity of MCF-7 cells.
-
Article
Influence of CYP3A5 genetic polymorphism on cyclosporine A metabolism and elimination in Chinese renal transplant recipients
To investigate whether the CYP3A5*3 polymorphism would affect cyclosporine A (CsA) metabolism in Chinese renal transplant patients.
-
Article
Granulocyte-macrophage colony-stimulating factor DNA prime-protein boost strategy to enhance efficacy of a recombinant pertussis DNA vaccine
To investigate a new strategy to enhance the efficacy of a recombinant pertussis DNA vaccine. The strategy is co-injection with cytokine plasmids as prime, and boosted with purified homologous proteins.
-
Article
Synergism of hydrochlorothiazide and nitrendipine on reduction of blood pressure and blood pressure variability in spontaneously hypertensive rats
To investigate the possible synergism of hydrochlorothiazide and nitrendipine on reducing both blood pressure (BP) and blood pressure variability (BPV) in spontaneously hypertensive rats (SHR).
-
Article
Modulation of inflammation-related genes of polysaccharides fractionated from mycelia of medicinal basidiomycete Antrodia camphorata
To investigate the effect of water soluble-ethanol precipitation fraction (AC-1) and alkaline extraction-isoelectric precipitation fraction (AC-2) from Antrodia camphorata (Polyporaceae, Aphyllophorales) on lipop...
-
Article
l-Stepholidine increases the frequency of sEPSC via the activation of D1 dopamine signaling pathway in rat prelimbic cortical neurons
To investigate the effect of l-stepholidine (SPD) on the frequency of spontaneous excitatory postsynaptic currents (sEPSC) in the pyramidal cells between layers V and VI in the prelimbic cortex (PL).
-
Article
Requirement of PSD-95 for dopamine D1 receptor modulating glutamate NR1a/NR2B receptor function
To elucidate the role of scaffold protein postsynaptic density (PSD)-95 in the dopamine D1 receptor (D1R)-modulated NR1a/NR2B receptor response.
-
Article
Minocycline inhibits 5-lipoxygenase activation and brain inflammation after focal cerebral ischemia in rats
To determine whether the anti-inflammatory effect of minocycline on postischemic brain injury is mediated by the inhibition of 5-lipoxygenase (5-LOX) expression and enzymatic activation in rats.
