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  1. The Porous SilMA Hydrogel Scaffolds Carrying Dual-Sensitive Paclitaxel Nanoparticles Promote Neuronal Differentiation for Spinal Cord Injury Repair

    BACKGROUND:

    In the intricate pathological milieu post-spinal cord injury (SCI), neural stem cells (NSCs) frequently differentiate into astrocytes...

    Zhixiang Li, Tao Zhou, ... Yingji Mao in Tissue Engineering and Regenerative Medicine
    Article 15 July 2024

  2. Platelet-Rich Plasma Promotes the Expansion of Human Myoblasts and Favors the In Vitro Generation of Human Muscle Reserve Cells in a Deeper State of Quiescence

    Stem cell therapy holds significant potential for skeletal muscle repair, with in vitro-generated human muscle reserve cells (MuRCs) emerging as a...

    Axel Tollance, Alexandre Prola, ... Thomas Laumonier in Stem Cell Reviews and Reports
    Article Open access 13 July 2024

  3. The Angiogenic Repertoire of Stem Cell Extracellular Vesicles: Demystifying the Molecular Underpinnings for Wound Healing Applications

    Stem cells-derived extracellular vesicles (SC-EVs) have emerged as promising therapeutic agents for wound repair, recapitulating the biological...

    Shuoyuan Liu, Huayuan Zhao, ... Zhenbing Chen in Stem Cell Reviews and Reports
    Article 13 July 2024

  5. Neurotransmitters at a glance

    Rita Strack in Nature Methods
    Article 12 July 2024

  6. Bats

    Liora Las, Nachum Ulanovsky in Nature Methods
    Article 12 July 2024

  7. Keypoint-MoSeq: parsing behavior by linking point tracking to pose dynamics

    Keypoint tracking algorithms can flexibly quantify animal movement from videos obtained in a wide variety of settings. However, it remains unclear...

    Caleb Weinreb, Jonah E. Pearl, ... Sandeep Robert Datta in Nature Methods
    Article Open access 12 July 2024

  9. Multiplexed base editing

    Madhura Mukhopadhyay in Nature Methods
    Article 12 July 2024

  10. Enzymatic synthesis of RNA oligonucleotides

    Marcel Hollenstein in Nature Biotechnology
    Article 12 July 2024

  11. Template-independent enzymatic synthesis of RNA oligonucleotides

    RNA oligonucleotides have emerged as a powerful therapeutic modality to treat disease, yet current manufacturing methods may not be able to deliver...

    Daniel J. Wiegand, Jonathan Rittichier, ... George M. Church in Nature Biotechnology
    Article Open access 12 July 2024

  12. Precise in vivo RNA base editing with a wobble-enhanced circular CLUSTER guide RNA

    Recruiting the endogenous editing enzyme adenosine deaminase acting on RNA (ADAR) with tailored guide RNAs for adenosine-to-inosine (A-to-I) RNA base...

    Philipp Reautschnig, Carolin Fruhner, ... Thorsten Stafforst in Nature Biotechnology
    Article Open access 12 July 2024

  13. Deep 3D histology powered by tissue clearing, omics and AI

    To comprehensively understand tissue and organism physiology and pathophysiology, it is essential to create complete three-dimensional (3D) cellular...

    Ali Ertürk in Nature Methods
    Article 12 July 2024

  17. Modified mesenchymal stromal cells by in vitro transcribed mRNA: a therapeutic strategy for hepatocellular carcinoma

    Background

    Mesenchymal stromal cells (MSCs) tropism for tumours allows their use as carriers of antitumoural factors and in vitro transcribed mRNA...

    María José Cantero, Barbara Bueloni, ... Mariana G. García in Stem Cell Research & Therapy
    Article Open access 11 July 2024

  18. Autotaxin Inhibition Reduces Post‐Ischemic Myocardial Inflammation via Epigenetic Gene Modifications

    Myocardial infarction (MI) triggers a complex inflammatory response that is essential for cardiac repair but can also lead to adverse outcomes if...

    Landys Z. Guo, Himi Tripathi, ... Ahmed Abdel-Latif in Stem Cell Reviews and Reports
    Article 10 July 2024

  19. CAR-Ts sweep into autoimmunity

    Charlotte Harrison in Nature Biotechnology
    Article 10 July 2024

  20. Redundancy of p75NTR neurotrophin receptor function in development, growth and fertility in the rat

    The p75NTR neurotrophin receptor has positive and negative roles regulating cell survival in the nervous system. Unambiguous interpretation of p75NTR...

    Stephen Meek, Karamjit Singh-Dolt, ... Tom Burdon in Transgenic Research
    Article Open access 09 July 2024
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