37 Result(s)
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Reference Work Entry
**an Zheng
Medicine & Public Health
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Living Reference Work Entry In depth
Cervical Cancer Development, Screening, and Prevention
Cervical cancer ranks as the fourth most common cancer in women globally with an estimated 604,000 new cases and 342,000 deaths in 2020. Most cases (75–85%) are squamous cell carcinomas (SCC), with a smaller p...
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Living Reference Work Entry In depth
Endometriosis and Endometriosis-Associated Tumors
Endometriosis is a chronic, estrogen-dependent, inflammatory disorder that affects ~10% of reproductive-aged women. The condition, characterized by the presence of endometrial glands and stroma outside of the ...
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Living Reference Work Entry In depth
Endometrial Carcinogenesis
The conventional dualistic model of endometrial cancer (types I and II) has been the mainstay in clinical practice for decades. However, recent advances show that this model does not capture the heterogeneity ...
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Living Reference Work Entry In depth
Unveiling Residual Diseases of Endometrial Precancer/Cancer After Progestin Therapy
The widespread use of progestin therapy for endometrial precancer/cancer introduces complexities in the interpretation of pathology specimens. This chapter delves into the nuanced morphological changes trigger...
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Living Reference Work Entry In depth
Peritoneum and Broad Ligament
The peritoneum is a site for diverse nonneoplastic and neoplastic disease processes, including those encountered in many other organ systems in the body. A recent theory is that Müllerian peritoneal/omental se...
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Reference Work Entry In depth
International Guideline on Natural Orifice Specimen Extraction Surgery (NOSES) for Colorectal Cancer (2023 Version)
Purpose: In recent years, natural orifice specimen extraction surgery (NOSES) has gained widespread attention as an alternative approach. Although the safety and feasibility of NOSES have been well documented, ma...
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Reference Work Entry In depth
Experience Sharing on Digestive Tract Reconstruction in NOSES
Since NOSES is a type of total laparoscopic surgery, the most difficult and least error-tolerant surgical step is totally laparoscopic digestive tract reconstruction. Different methods of digestive tract recon...
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Reference Work Entry In depth
Laparoscopic Ultralow Rectal Cancer Resection with Transanal Specimen Extraction: Intersphincteric Resection Method (CRC-NOSES ID)
NOSES ID is mainly applicable to patients with lower and ultralow rectal cancer with good mobility. Laparoscopic operation should strictly follow the principles of total mesorectal excision (TME). The characte...
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Reference Work Entry In depth
Laparoscopic Extended Lower Rectal Cancer Resection with En Bloc Lateral Lymph Node Dissection (Wang’s Approach)
Lateral lymph node metastasis of middle and lower rectal cancer is an objective fact and a route of lymphatic drainage of the rectum. The incidence of lateral lymph node metastasis is reported to be 9–25%, whi...
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Reference Work Entry In depth
Laparoscopic Left Hemicolectomy with Transrectal Specimen Extraction (CRC-NOSES VIB)
For patients with tumors located at the splenic flexure or left transverse colon, specimen extraction through the sigmoid colon is often difficult because the tumor is located far from the anus. For such patie...
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Reference Work Entry In depth
Laparoscopic Total Colectomy with Transvaginal Specimen Extraction (CRC-NOSES X)
Total colectomy is one of the most difficult and complex techniques in colorectal surgery involving complex surgical procedures and a wide resection range. Compared with conventional laparoscopic total colecto...
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Reference Work Entry In depth
Transvaginal Radical Resection of Rectal Cancer Through Rigid Endoscopy (Rectal Tv-NOTES)
Under the impact of the NOTES concept, Professor Wang **shan took the lead in conducting two cases of NOTES for rectal tumor in 2010. The surgery went smoothly, the patients had a quick recovery and showed goo...
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Reference Work Entry In depth
Laparoscopic Abdominal Pelvic Anatomical Landmarks and Essentials of Surgical Exploration
In conventional open surgery, the surgeon carries out the operation depending on the visualization and haptic sensations of the affected tissue directly. With the continuous development of the laparoscopic tec...
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Reference Work Entry In depth
Laparoscopic Ultralow Rectal Cancer Resection with Transanal Specimen Extraction: Park Method (CRC-NOSES IC)
The special anatomical location of lower rectal cancer makes anus-preserving surgery more challenging. Although the double stapling technique increases the chance of anus preservation, it is still difficult to...
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Reference Work Entry In depth
International Consensus on Natural Orifice Specimen Extraction Surgery (NOSES) for Gastric Cancer (2019)
At present, natural orifice specimen extraction surgery (NOSES) has attracted more and more attention worldwide, because of its great advantages including minimal cutaneous trauma and postoperative pain, fast ...
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Reference Work Entry In depth
Laparoscopic Left Hemicolectomy with Transanal Specimen Extraction (CRC-NOSES VI A)
The relative low incidence of left colon cancer (only accounting for 5–6% of colon cancer), with some cases of sclerotic type accompanied by obstructive symptoms, leads to a lower amount of experience in NOSES...
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Reference Work Entry In depth
Laparoscopic Left Hemicolectomy with Transvaginal Specimen Extraction (CRC-NOSES VII)
NOSES VII is mainly applicable to female patients with larger tumors located at the left-sided colon. The main operating features of this procedure include totally laparoscopic dissection and transection of th...
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Reference Work Entry In depth
Laparoscopic Total Colectomy with Transanal Specimen Extraction (CRC-NOSES IX)
NOSES IX is completed on the basis of laparoscopic total colectomy combined with unique digestive tract reconstruction and transanal specimen extraction. The main operating features of this procedure include c...
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Reference Work Entry In depth
Comprehensive Experience Sharing on NOSES
Different surgeons have gradually developed their own distinctive understanding of NOSES in clinical practice. In addition to standard surgical methods, experts from different hospitals have adapted and improv...
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Reference Work Entry In depth
From Anti-Parkinson’s Drug Rasagiline to Novel Multitarget Iron Chelators with Acetylcholinesterase and Monoamine Oxidase Inhibitory and Neuroprotective Properties for Alzheimer’s Disease
Alzheimer’s disease (AD) is a multifactorial syndrome involving a complex array of different, while related factors in its progression. Accordingly, novel approaches that can simultaneously modulate several di...
