Skip to main content

and
  1. No Access

    Protocol

    3D-Autologous Culture Method for Precision Oncology

    The 3D-autologous culture method (3D-ACM) for patient-derived cancer samples utilizes a patient’s own body fluid or serum to prepare a 3D scaffold and for the culture medium. 3D-ACM enables tumor cells and/or ...

    Qian Xu, Meiling Yan, Yao Tang in Cancer Systems and Integrative Biology (2023)

  2. No Access

    Protocol

    The Detection of Exosomal PD-L1 in Peripheral Blood

    Peripheral blood is a source for liquid biopsy, which can meet the requirements of pretreatment disease ty** to determine precise targeted therapy and monitoring of posttreatment minimal residual disease mon...

    Rui Wang, Yanjia Yang, Jiajun Huang, Yandan Yao in Liquid Biopsies (2023)

  3. No Access

    Protocol

    Functional Interrogation of Ca2+ Signals in Human Cancer Cells In Vitro and Ex Vivo by Fluorescent Microscopy and Molecular Tools

    Genetically encoded calcium indicators (GECIs) and high-resolution confocal microscopy enable dynamic visualization of calcium signals in cells and tissues. Two-dimensional and 3D biocompatible materials mimic...

    Chenyu Liang, Miao Huang, Mai Tanaka in Microfluidic Systems for Cancer Diagnosis (2023)

  4. No Access

    Protocol

    Develo** and Using a Data Commons for Understanding the Molecular Characteristics of Germ Cell Tumors

    Germ cell tumors (GCTs) are a rare disease, but they account for 15% of all malignancies diagnosed during adolescence. The biological mechanisms underpinning their development are only starting to be explored....

    Bo Ci, Shin-Yi Lin, Bo Yao, Danni Luo, Lin Xu, Mark Krailo in Testicular Germ Cell Tumors (2021)

  5. No Access

    Protocol

    Assessing Neurological Function in Brain Tumor Mouse Model

    Of all cancer types, brain cancers often constitute the most devastating and difficult-to-treat tumors. In the United States, brain cancer accounts for 1 in every 100 cancer diagnoses. Although significant adv...

    **ng Gao, Limeng Wu, Raquel D. Thalheimer, Jie Chen, Yao Sun, Grace Y. Lee in Brain Tumors (2021)

  6. No Access

    Protocol

    Deep Sequencing Reveals a MicroRNA Expression Signature in Triple-Negative Breast Cancer

    Deep sequencing is an advanced technology in genomic biology to detect the precise order of nucleotides in a strand of DNA/RNA molecule. The analysis of deep sequencing data also requires sophisticated knowled...

    Yao-Yin Chang Ph.D, Liang-Chuan Lai, Mong-Hsun Tsai in MicroRNA and Cancer (2018)

  7. No Access

    Protocol

    LC-MS-Based Metabolomic Investigation of Chemopreventive Phytochemical-Elicited Metabolic Events

    Phytochemicals are under intensive investigation for their potential use as chemopreventive agents in blocking or suppressing carcinogenesis. Metabolic interactions between phytochemical and biological system ...

    Lei Wang, Dan Yao, Chi Chen in Cancer Chemoprevention (2016)

  8. No Access

    Protocol

    Autoantibodies Against Cancer Antigens

    With the identification of tumor antigens, the host immune response to various types of cancers can now be studied with a high degree of specificity in large cohorts of patients, in the hope of correlating imm...

    Sacha Gnjatic, Lloyd J. Old, Yao-Tseng Chen in Tumor Biomarker Discovery (2009)