7 Result(s)
within
Protocol
Shi ** Chen
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Protocol
Predicting RNA Scaffolds with a Hybrid Method of Vfold3D and VfoldLA
The ever-increasing discoveries of noncoding RNA functions draw a strong demand for RNA structure determination from the sequence. In recently years, computational studies for RNA structures, at both the two-d...
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Protocol
The Gene Balance Hypothesis: Epigenetics and Dosage Effects in Plants
Dosage effects in plants are caused by changes in the copy number of chromosomes, segments of chromosomes, or multiples of individual genes. Genes often exhibit a dosage effect in which the amount of product i...
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Protocol
Predicting RNA Structure with Vfold
In order to carry out biological functions, RNA molecules must fold into specific three-dimensional (3D) structures. Current experimental methods to determine RNA 3D structures are expensive and time consuming...
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Protocol
A New Method to Predict Ion Effects in RNA Folding
The strong interaction between metal ions in solution and highly charged RNA molecules is critical for RNA structure formation and stabilization. Metal ions binding to RNA can induce RNA structural changes tha...
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Protocol
A Method to Predict the Structure and Stability of RNA/RNA Complexes
RNA/RNA interactions are essential for genomic RNA dimerization and regulation of gene expression. Intermolecular loop–loop base pairing is a widespread and functionally important tertiary structure motif in R...
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Protocol
A Method to Predict the 3D Structure of an RNA Scaffold
The ever increasing discoveries of noncoding RNA functions draw a strong demand for RNA structure determination from the sequence. In recently years, computational studies for RNA structures, at both the two-d...
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Protocol
Comparative Transcriptome Analysis for Metabolic Engineering
Transcriptome profiling allows massively parallel analysis of the dynamic expression of all genes and captures the cell physiology and regulatory mechanism in a holistic manner. Compared to other “omic” techni...
