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    Flow Cytometry-Based Detection of Siglec Ligands

    Siglecs are a family of immunomodulatory cell surface receptors present on white blood cells. Binding to cell surface sialic acid-containing glycans modulates the proximity of Siglecs to other receptors that t...

    Edward N. Schmidt, Jaesoo Jung, Matthew S. Macauley in Carbohydrate-Protein Interactions (2023)

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    Qualitative and Quantitative Characterization of Protein–Carbohydrate Interactions by NMR Spectroscopy

    Solution-state nuclear magnetic resonance (NMR) spectroscopy can be used to monitor protein–carbohydrate interactions. Two-dimensional 1H-15N heteronuclear single quantum coherence (HSQC)-based techniques describ...

    Julie M. Grondin, David N. Langelaan, Steven P. Smith in Carbohydrate-Protein Interactions (2023)