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    Protocol

    Hi-M: A Multiplex Oligopaint FISH Method to Capture Chromatin Conformations In Situ and Accompanying Open-Source Acquisition Software

    The simultaneous observation of three-dimensional (3D) chromatin structure and transcription in single cells is critical to understand how DNA is organized inside cells and how this organization influences or ...

    Jean-Bernard Fiche, Marie Schaeffer… in Fluorescence In Situ Hybridization (FISH) (2024)

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    Protocol

    DNA Organization and Superesolved Segregation

    With single-molecule localization microscopy (SMLM) it is possible to reveal the internal composition, architecture, and dynamics of molecular machines and large cellular complexes. SMLM remains technically ch...

    Diego I. Cattoni, Jean-Bernard Fiche, Antoine Le Gall, Marcelo Nollmann in Molecular Motors (2018)