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    Reconstitution of CHIP E3 Ubiquitin Ligase Activity

    CHIP, the carboxyl-terminus of Hsp70 interacting protein, is both an E3 ubiquitin ligase and an Hsp70 co-chaperone and is implicated in the degradation of cytosolic quality control and numerous disease substra...

    Hong Yu Ren, Cam Patterson, Douglas M. Cyr, Meredith F. N. Rosser in Molecular Chaperones (2011)