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    Protocol

    In vivo Techniques Quantifying Blood-Brain Barrier Permeability to Small Proteins in Mice

    The blood–brain barrier (BBB) plays a crucial regulatory role in central nervous system (CNS) function and in communication between the CNS and the periphery. In addition to lipophilic molecules, many small pr...

    Weihong Pan, Abba J. Kastin in Neuropeptide Techniques (2008)

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    Protocol

    Measurement of Efflux Rates from Brain to Blood

    The blood-brain barrier (BBB) regulates the exchange of substances between the fluids of the central nervous system (CNS) and the blood (1). As such, the BBB is actively involved in providing nutrition and mainta...

    William A. Banks, Melita B. Fasold, Abba J. Kastin in Neuropeptide Protocols (1997)