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    Protocol

    Determination of Metal Interactions with the Chaperone Hspa5 in Human Astrocytoma Cells and Rat Astrocyte Primary Cultures

    Molecular chaperones assist the folding of nascent proteins during translation into their correct conformations. Neurotoxic metals such as copper (Cu) and lead (Pb) may produce a deficiency in chaperone functi...

    Evelyn Tiffany-Castiglioni, Yongchang Qian, Rola Barhoumi… in In Vitro Neurotoxicology (2011)

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    Protocol

    Cell-Type Specific Responses of the Nervous System to Lead

    Cells that make up the nervous system interact in complex, dynamic structural and biochemical contexts to generate organ function. A neurotoxicant that alters the activities of a particular cell type also indu...

    Evelyn Tiffany-Castiglioni, Yongchang Qian in In Vitro Neurotoxicology (2004)