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    Protocol

    Genetic Studies of Tic Disorders and Tourette Syndrome

    Tourette syndrome (TS) is a complex disorder characterized by repetitive, sudden, and involuntary movements or vocalizations, called tics. Tics usually appear in childhood, and their severity varies over time....

    Yanjie Qi, Yi Zheng, Zhanjiang Li, Zhisheng Liu, Lan **ong in Psychiatric Disorders (2019)

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    Protocol

    Microiontophoretic Study of Individual Neurons During Intracellular Recording

    There is an increasing tendency to combine multidisciplinary methods in studying the central nervous systems. One recently developed technique is the combination of electrophysiological and pharmacological inv...

    Qi-Jian Sun, Paul M. Pilowsky in Stimulation and Inhibition of Neurons (2013)

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    Protocol

    Imaging Single Synaptic Vesicles in Mammalian Central Synapses with Quantum Dots

    This protocol describes a sensitive and rigorous method to monitor the movement and turnover of single synaptic vesicles in live presynaptic terminals of mammalian central nervous system. This technique makes ...

    Qi Zhang in Chemical Neurobiology (2013)

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    Protocol

    Converging Methodologies in a Mammalian “Simple System” Focused on the Biology of Memory: Conditioned Odor Preference in the Neonate Rat

    We present here a critical period model for odor preference learning in the rat pup, which can produce short-term or lifelong changes in odor-related behaviors depending on training parameters. Features which ...

    Qi Yuan, Carolyn W. Harley, John H. McLean in Multidisciplinary Tools for Investigating … (2013)

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    Labeling Stem Cells In Vitro for Identification of their Differentiated Phenotypes after Grafting into the CNS

    Grafting neural stem cells is a widely used experimental approach to central nervous system (CNS) repair after trauma or neurodegeneration. It is likely to be a realistic clinical therapy for human CNS disorde...

    Qi-lin Cao MD, PhD, Stephen M. Onifer PhD, Scott R. Whittemore PhD in Neural Stem Cells (2008)

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    Protocol

    Labeling Stem Cells In Vitro for Identification of Their Differentiated Phenotypes After Grafting into the CNS

    Stem cells have unlimited therapeutic potential for restoring CNS function lost secondary to trauma or degenerative disease. To date, stem cell grafts have only in a few instances partially ameliorated functio...

    Qi-lin Cao, Stephen M. Onifer in Neural Stem Cells: Methods and Protocols (2002)

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    Protocol

    Electrophysiological Studies on Receptors In Vitro

    In the past 20 years that in vitro preparations of central nervous system (CNS) cells have been used to access excitable membrane properties with electrophysiological techniques, there have been remarkable cha...

    Qi-Ying Liu, Anne E. Schaflner, jeffery L. Barker in In Vitro Neurochemical Techniques (1999)