6 Result(s)
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Protocol
Measuring Drp1 Activity in Mitochondrial Fission In Vivo
Mitochondrial fission is mainly regulated by a number of dynamin superfamily proteins or DSPs, of which dynamin-like protein 1 (Drp1) is responsible for the scission process during mitochondrial fission. Here ...
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Protocol
Quantifying Drp1-Mediated Mitochondrial Fission by Immunostaining in Fixed Cells
Dynamin-like protein 1 (Drp1) is the master regulator of mitochondrial fission. Drp1 translocates from the cytosol to the mitochondrial outer membrane to execute the scission process. Here we describe an immun...
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Protocol
Structural Characterization of Silk Fibers by Small-Angle X-Ray Scattering
Nature is rich in all kinds of unbelievably designed microstructures, which endows the natural materials with various fantastic performances. Unveiling the mystery of the sophisticated configurations and the r...
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Protocol
Discovery of Covalent Drugs Targeting the Key Enzymes of SARS-CoV-2 Using SCARdock
Historically, covalent drugs were avoided in drug development process due to the possible toxicity linked to the covalent binding of such drugs and cellular proteins. However, recent years have witnessed the f...
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Protocol
A Hybrid Biological–Biomaterial Vector for Antigen Delivery
A hybrid biological–biomaterial vector composed of a biocompatible polymeric biomaterial coating and an Escherichia coli core was designed and developed for antigen delivery. It provides a unique and efficient me...
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Protocol
Structural Characterization of Silk Fibers by Wide-Angle X-Ray Scattering
As one of the most advanced techniques to gain insight into the structure of the materials, wide-angle X-ray scattering (WAXS) records the scattering information at wide angles which typically larger than 5° (2θ)...
