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Functional and clinical roles of stromal PDGF receptors in tumor biology
PDGF receptors play pivotal roles in both developmental and physiological processes through the regulation of mesenchymal cells involved in paracrine...
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Evaluating the Impact of an Organic Trace Mineral mix on the Redox Homeostasis, Immunity, and Performance of Sows and their Offspring
The objective of the study was to evaluate the effects of trace mineral supplementation in sows during gestation and lactation on the performance and...
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Methadone versus other opioids for refractory malignant bone pain: a pilot randomised controlled study
PurposeRefractory cancer-induced bone pain (CIBP) affects a patient’s functional capacity and quality of life, but there is limited evidence to guide...
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Characterizing disparities in receipt of palliative care for Asian Americans, Native Hawaiians, and Pacific Islanders with metastatic cancer in the United States
PurposePalliative care plays essential roles in cancer care. However, differences in receipt among individuals identifying as Asian American, Native...
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The evolution of the multidisciplinary tumor board in orthopedic oncology: from its historical roots to its future potential
PurposeThe purpose of this review is to summarize the impact of the multidisciplinary tumor board as a tool or mechanism for orthopedic oncology...
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An Ode to the Heart from Down Under!
Testicular malignancies rarely metastasize to the heart. Cardiac metastases often herald disseminated disease. It can manifest either in a...
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A positive feedback loop between PFKP and c-Myc drives head and neck squamous cell carcinoma progression
BackgroundThe aberrant expression of phosphofructokinase-platelet (PFKP) plays a crucial role in the development of various human cancers by...
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The role of hydrogen sulfide regulation of ferroptosis in different diseases
Ferroptosis is a programmed cell death that relies on iron and lipid peroxidation. It differs from other forms of programmed cell death such as...
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Internal Mammary Lymphadenopathy Does Not Impact Oncologic Outcomes in Patients Treated with Neoadjuvant Chemotherapy: Results from the I-SPY2 Clinical Trial
BackgroundInternal mammary lymphadenopathy (IML) plays a role in breast cancer stage and prognosis. We aimed to evaluate method of IML detection, how...
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Long-term consequences of positive surgical margin after partial nephrectomy for renal cell carcinoma: multi‐institutional analysis
IntroductionThe aim of the study was to determine the impact of positive surgical margins (PSM) after PN on very long-term recurrence in a...
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Synthetic magnetic resonance-based relaxometry and brain volume: cutoff values for predicting neurocognitive outcomes in very preterm infants
BackgroundEarly neurorehabilitation can enhance neurocognitive outcomes in very preterm infants (<32 weeks), and conventional magnetic resonance...
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Baseline and early 18F-FDG PET/CT evaluations as predictors of progression-free survival in metastatic breast cancer patients treated with targeted anti-CDK therapy
BackgroundExploring the value of baseline and early 18 F-FDG PET/CT evaluations in prediction PFS in ER+/HER2- metastatic breast cancer patients...
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Synthetic CT generation for pelvic cases based on deep learning in multi-center datasets
Background and purposeTo investigate the feasibility of synthesizing computed tomography (CT) images from magnetic resonance (MR) images in...
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Oral antivirals for COVID-19 among patients with cancer
PurposeImmunocompromised individuals, such as those diagnosed with cancer, are at a significantly higher risk for severe illness and mortality when...
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Mechanical deformation and death of circulating tumor cells in the bloodstream
The circulation of tumor cells through the bloodstream is a significant step in tumor metastasis. To better understand the metastatic process,...
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Predicting relapsed/refractory disease in childhood hemophagocytic lymphohistiocytosis based on clinical features at diagnosis: A 13-year single-institute retrospective study in Thailand
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disease. Relapsed/refractory disease is the main cause of death. This study aims to...
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Patient-Reported Outcomes in Chinese Patients with Locally Advanced or Recurrent Colorectal Cancer After Pelvic Exenteration
BackgroundPelvic exenteration (PE) is often the only curative treatment option for selected locally advanced and locally recurrent colorectal cancer...