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Chapter and Conference Paper
Basic mechanisms of brain inflammation
The mechanisms, how the immune system surveys the nervous tissue and how brain inflammation is regulated are essential questions for therapy of neuroimmunological diseases. The nervous system is continuously p...
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Chapter and Conference Paper
Myelin dysfunction/degradation in the central nervous system: why are myelin sheaths susceptible to damage?
In the central nervous system, myelin sheaths are produced to electrically insulate axons and to increase the velocity of axonal conduction. They are highly complex structures, which are often destructed in ne...
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Chapter and Conference Paper
Mechanisms of tissue injury in multiple sclerosis: opportunities for neuroprotective therapy
Development of neuroprotective therapies for multiple sclerosis is dependent on defining the precise mechanisms whereby immune effector cells and molecules are able to induce relatively selective injury of oli...
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Chapter and Conference Paper
Target Discovery and Validation
The pharmaceutical industry as we know it is still relatively young and only started to emerge about 100 years ago, as advances in chemistry and biology made the discovery and synthesis of drugs possible. In t...
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Chapter and Conference Paper
New Therapeutics Targets in Chronic Viral Cardiomyopathy
Dilated cardiomyopathy (DCM) is a prevalent heart muscle disease characterized by impaired contractility and dilation of the ventricles. Recent clinical research suggests that cardiotropic viruses are importan...
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Chapter and Conference Paper
Counteraction to CBRN Terrorism in Switzerland
In Switzerland, the planning of security policy measures now increasingly factors in scenarios involving the use of CBRN weapons on Swiss soil. While there have been no terrorist “spectaculars” or dramatic new...
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Chapter and Conference Paper
Strategies of Preparedness Response to Biological Warfare and Bioterrorism Threats
Risks associated with deliberate use of biological agents against population and the needs for a strong public health system are well recognized. The potential use of biological agents is mounting every day, e...
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Chapter and Conference Paper
Infections Diseases in the Context of Terrorist Threat
From the great number of pathogenic and conventionally pathogenic for human beings microorganisms, only some of them can be used for terroristic purposes, since they should meet a lot of the relevant propertie...