29 Result(s)
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English
Medicine & Public Health
Metabolic Diseases
Rheumatology
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Conference Paper
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Chapter and Conference Paper
Introduction
Disturbances of iron metabolism, particularly iron deficiency and iron redistribution are among the most commonly overlooked or misinterpreted diseases. This is due to the fact that the determination of transp...
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Chapter and Conference Paper
Disturbances of Iron Metabolism/Disturbances of Erythropoiesis and Hemolysis
An impaired iron balance of the body can frequently be described as a discordant regulation of synthesis of ferritin, the iron storage protein, on the one hand, and of the transferrin receptor, the indicator o...
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Chapter and Conference Paper
Therapy of Anemias
Anemias are a worldwide problem. Severe anemia affects mainly older men and women. The WHO defines anemia as a hemoglobin concentration of less than 12 g/dl in women and less than 13 g/dl in men (World Health ...
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Chapter and Conference Paper
Physiological Principles of Iron Metabolism and Erythropoiesis
Iron, as a constituent of hemoglobin and cytochromes, is one of the most important biocatalysts in the human body.
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Chapter and Conference Paper
Diagnosis of Disturbances of Iron Metabolism Disturbances of Erythropoiesis
Knowledge of physiological principles and the acquisition of clinical laboratory data are tools used by the doctor in clinical practice. However, it is becoming increasingly difficult to interpret the mass of ...
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Chapter and Conference Paper
Methods
The methods of determination for the blood count, the iron metabolism and for inflammation are only described in principle; the listed references allow the reader to obtain further and more detailed informatio...
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Chapter and Conference Paper
Introduction
Disturbances of iron metabolism, particularly iron deficiency and iron redistribution are among the most commonly overlooked or misinterpreted diseases. This is due to the fact that the determination of transp...
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Chapter and Conference Paper
Erythropoiesis
An adult has on average 5 liters of blood and an erythrocyte count of 5 × 106/μl, giving a total erythrocyte count of 2.5 × 1013. Since the mean life span of an erythrocyte is normally 120 days, about 2 × 1011 ne...
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Chapter and Conference Paper
Diagnosis of Disturbances of Iron Metabolism Disturbances of Erythropoiesis
Life-threatening clinical states are very rare occurrences in the majority of anemia diagnoses. An important component of therapy, therefore, is to determine the cause of the anemia, classify it, and eliminate...
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Chapter and Conference Paper
Disturbances of Iron Distribution Diagnosis and Therapy
Chronic infections, tumors, chronic inflammations and autoimmune diseases “need” iron and withdraw it from hematopoiesis. “Secondary anemias”, “anemias of infection or tumor anemias” or anemias of chronic dise...
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Chapter and Conference Paper
Iron Overload
The human body is incapable of actively excreting excess iron. An overabundant supply of iron leads to increased concentrations of the iron storage proteins ferritin and hemosiderin. If the storage capacity is...
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Chapter and Conference Paper
Non-iron-induced Disturbances of Erythropoiesis
Deficiencies in vitamin B12, folic acid and/or erythropoietin have been found to be crucial factors in non-iron-deficiency-induced forms of anemia.
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Chapter and Conference Paper
References
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Chapter and Conference Paper
Iron Metabolism
Iron, as a constituent of hemoglobin and cytochromes, is one of the most important biocatalysts in the human body.
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Chapter and Conference Paper
Disturbances of Iron Metabolism/Disturbances of Erythropoiesis and Hemolysis
An impaired iron balance of the body can frequently be described as a discordant regulation of synthesis of ferritin, the iron storage protein, on the one hand, and of the transferrin receptor, the indicator o...
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Chapter and Conference Paper
Iron Deficiency — Diagnosis and Therapy
In the case of a negative iron balance, the iron stores are reduced first; this can be seen from the measurement of ferritin. The concentration of active iron decreases only at a relatively late stage (as show...
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Chapter and Conference Paper
Disturbances of Iron Utilization Diagnosis and Therapy
In patients with disturbances of iron utilization, the individual erythrocyte contains a normal amount of hemoglobin despite the lowering of the patient’s hemoglobin value. MCH and MCV are normal. Iron deficie...
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Chapter and Conference Paper
Methods of Determination in Serum/Plasma and Blood
The methods of determination for plasma proteins, the blood count and for inflammation are only described in principle; the listed references allow the reader to obtain further and more detailed information. T...
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Chapter and Conference Paper
Erythropoiesis
An adult has on average 5 liters of blood and an erythrocyte count of 5 × 106/μL, giving a total erythrocyte count of 2.5 × 1013. Since the mean life span of an erythrocyte is normally 120 days, about 2×1011 new ...
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Chapter and Conference Paper
Diagnosis of Disturbances of Iron Metabolism
Disturbances of iron metabolism are mainly due to disturbances in iron balance which, in turn, are mainly due to disturbances in the resorption of iron or iron losses. Therefore, the uptake of iron occupies th...
