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Conference Paper
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Chapter and Conference Paper
Role of VLC-PUFAs in Retinal and Macular Degeneration
Very-long-chain polyunsaturated fatty acids (VLC-PUFAs) are a special class of fatty acids that are present in the retina and a few other human tissues. They cannot be synthesized de novo and are rarely presen...
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Chapter and Conference Paper
Perceived Social Support in Parents of Hospitalized Children During COVID-19
It was March 2020 when the World Health Organization declared a global pandemic due to the spread of a virus known as SARS-CoV-2, which started in Wuhan (China) and spread across the world. From that time onwa...
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Chapter and Conference Paper
Human Mutations in Arl3, a Small GTPase Involved in Lipidated Cargo Delivery to the Cilia, Cause Retinal Dystrophy
Photoreceptors are highly polarized sensory neurons. Precise localization of signaling molecules within the ciliary outer segment is critical for photoreceptor function and viability. The small GTPase Arl3 pla...
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Chapter and Conference Paper
Job Satisfaction and Burnout Levels of the Human Resources of a Public Oncology Hospital During the COVID-19 Pandemic
To investigate job satisfaction and burnout levels among the personnel of a public oncology hospital amid the COVID-19 pandemic, a cross-sectional survey was designed. The study was carried out from December 2...
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Chapter and Conference Paper
Inhibition of Bacterial Peptidoglycan Cytopathy by Retina Pigment Epithelial PGRP2 Amidase
Peptidoglycan (PGN) recognition protein 2 (PGRP2; N-acetylmuramyl-l-alanine amidase (NAMAA)) activity in corneal epithelial cells is thought to inhibit corneal inflammation by reducing the PGN-induced cytokines. ...
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Chapter and Conference Paper
Endosymbiosis in Nature and the Gut-Brain Axis
Exploring the origin of is an interesting theme for study because it enhances our knowledge of the basis of . , which are organelles, are actually the major sites of photosynthesis in eukaryotic cells. a...
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Chapter and Conference Paper
Retinal Organoids: A Human Model System for Development, Diseases, and Therapies
Inherited retinal degenerations (IRD) encompasses a group of heterogeneous disorders causing debilitating visual diseases and blindness, affecting more than two million people worldwide, in all age groups. The...
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Chapter and Conference Paper
Detection and Quantification of Exhaled Breath Condensate and Dyspnea Correlation in Stable COPD: A Proof-of-Concept Study
The existing research data are still not able to provide an answer to the issue of the correlation between dyspnea and inflammation in stable chronic obstructive pulmonary disease (COPD). The purpose of this s...
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Chapter and Conference Paper
Photoreceptor Ion Channels in Signaling and Disease
Photoreceptors (PRs) in the neural retina convert photon capture into an electrical signal that is communicated across a chemical synapse to second-order neurons in the retina and on through the rest of the vi...
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Chapter and Conference Paper
Retinal Pathoconnectomics: A Window into Neurodegeneration
Over the past decade, the field of retinal connectomics has made huge strides in describing the precise topologies underlying retinal visual processing. The same techniques that allowed these advancements are ...
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Chapter and Conference Paper
Better Understand to Better Predict Subjective Well-Being Among Older Greeks in COVID-19 Era: Depression, Anxiety, Attitudes Towards eHealth, Religiousness, Spiritual Experience, and Cognition
Despite similarities with previous pandemics, the potential physical and psychosocial impact of COVID-19 on older adults is still little investigated in Greece. This study examines the intercorrelations betwee...
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Chapter and Conference Paper
The Amphipathic Helix in Visual Cycle Proteins: A Review
The visual cycle is a complex biological process that involves the sequential action of proteins in the retinal pigment epithelial (RPE) cells and photoreceptors to modify and shuttle visual retinoids. A major...
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Chapter and Conference Paper
Molecular Docking Studies of Phyllanthus niruri Root Phytoconstituents for Antibreast Cancer Activity Using Multiple Proteins
The systematic exploitation of the structural variety of natural products is made possible by docking studies, which have been shown to be a crucial technique. The objective of the current work was to use mole...
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Chapter and Conference Paper
Primary Retinal Cell Cultures as a Model to Study Retina Biology
Since its inception, primary retinal cultures have been an in vitro tool for modeling the in vivo environment of the retina for biological studies on development and disease. They offer simple and controlled e...
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Chapter and Conference Paper
Pathological Roles of INPP5D in Alzheimer’s Disease
Current hypothesis of Alzheimer’s disease (AD) postulates that amyloid β (Aβ) deposition in the brain causes tau inclusion in neurons and leads to cognitive decline. The discovery of the genetic association be...
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Chapter and Conference Paper
The Role of Gene Expression Regulation on Genetic Risk of Age-Related Macular Degeneration
Age-related macular degeneration (AMD) is a major cause of irreversible vision loss in the elderly. It is a complex multifactorial disease that is caused by the cumulative impact of genetic predisposition, env...
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Chapter and Conference Paper
An Updated Evolutionary and Structural Study of TBK1 Reveals Highly Conserved Motifs as Potential Pharmacological Targets in Neurodegenerative Diseases
TANK-binding kinase 1 protein (TBK1) is a kinase that belongs to the IκB (IKK) family. TBK1, also known as T2K, FTDALS4, NAK, IIAE8, and NF-κB, is responsible for the phosphorylation of the amino acid residues...
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Chapter and Conference Paper
The Noncanonical Role of Complement Factor H in Retinal Pigment Epithelium (RPE) Cells and Implications for Age-Related Macular Degeneration (AMD)
Age-related macular degeneration (AMD) is a complex degenerative disease of the retina. Dysfunction of the retinal pigment epithelium (RPE) occurs in early stages of AMD, and progressive RPE atrophy leads to p...
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Chapter and Conference Paper
Extracellular Matrix: The Unexplored Aspects of Retinal Pathologies and Regeneration
Nearly a billion people worldwide are affected by vision-impairing conditions, with retinal degenerative diseases being a major cause of blindness. Unfortunately, such diseases are often permanent and progress...
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Chapter and Conference Paper
Nursing Students’ Computer Anxiety and Attitudes Before and During the COVID-19 Pandemic
Purpose of this research was to investigate how the COVID-19 pandemic affected the level of computer anxiety of nursing students and also their attitude related to computer use. A cross-sectional study was con...
