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    Chapter and Conference Paper

    HybridTuner: Tuning with Hybrid Derivative-Free Optimization Initialization Strategies

    To utilize the full potential of advanced computer architectures, algorithms often need to be tuned to the architecture being used. We propose two hybrid derivative-free optimization (DFO) methods to maximize ...

    Benjamin Sauk, Nikolaos V. Sahinidis in Learning and Intelligent Optimization (2021)

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    Chapter and Conference Paper

    Heat Exchanger Circuitry Design by Decision Diagrams

    The interconnection pattern between the tubes of a tube-fin heat exchanger, also referred to as its circuitry, has a significant impact on its performance. We can improve the performance of a heat exchanger by...

    Nikolaos Ploskas, Christopher Laughman in Integration of Constraint Programming, Art… (2019)

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    Chapter and Conference Paper

    A Branch-and-Reduce Algorithm for the Contact Map Overlap Problem

    A fundamental problem in molecular biology is the comparison of 3-dimensional protein folds in order to develop similarity measures and exploit them for protein clustering, database searches, and drug design. ...

    Wei **e, Nikolaos V. Sahinidis in Research in Computational Molecular Biology (2006)

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    Chapter and Conference Paper

    Global Optimization and Constraint Satisfaction: The Branch-and-Reduce Approach

    In the early 1990s, we proposed the integration of constraint programming and optimization techniques within the branch-and-bound framework for the global optimization of nonconvex nonlinear and mixed-integer ...

    Nikolaos V. Sahinidis in Global Optimization and Constraint Satisfaction (2003)